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How to keep your brain healthy. It's a subject that desperately needs attention and is the mission of the drperlmutter.com blog. Categories are listed to the right and lead to empowering information on topics such as maintaining brain health and improving memory through a gluten free diet. We update this information as soon as it becomes available so check back often!

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The Science Behind Why “Low Alcohol” Wine Matters for Your Health

By: The Dr. Perlmutter Team

Alcohol is one of the most controversial topics health and wellness practitioners must navigate. Frequently, readers of this blog ask if alcohol consumption can be a part of a healthy lifestyle — my answer is, it depends.

Many studies have shown that alcohol consumption may have benefits far beyond easing social interaction and improving dance floor performance. A meta-analysis of the literature conducted in 2015 by the Journal of Internal Medicine found that moderate alcohol consumption is associated with reduced risk for coronary artery disease, stroke, and heart failure. However, that same study also found that heavy drinking, defined as consuming three or more standard-sized drinks per day, is associated with increased risk of high blood pressure, coronary artery disease, abnormalities in heart rhythm, and brain bleeding type stroke. How can alcohol consumption be associated with both an increased and decreased risk of coronary artery disease and stroke? Continue reading

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The Insulin Sweet Spot: Is Lower Better?

We commonly think that if something is good for our health, that more of it is even better, right? More kale never hurt anyone. Putting on extra sunscreen may not protect us from even more UV rays, but it certainly won’t cause excess damage!

But is that actually always true? How about with insulin, which we’re commonly told to keep as low as possible? Continue reading

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Am I in Ketosis? Four Simple Steps to Find Out!

We’ve talked a lot about the benefits of being in ketosis lately, but do you know how do you determine if you are in this state?

Science has given us a number of methods for doing so, including breath tests, urine tests, and blood tests. To be certain, each has their own advantages and disadvantages, but I tend to fall on the side of advocating for blood-based testing, which measures your level of the chemical beta-hydroxybutyrate (BHB). Continue reading

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You Can Reduce Your Risk for Parkinson’s Disease!

As we have explored previously, elevated blood sugar is clearly toxic for the brain. Higher blood sugar is clearly a risk for Alzheimer’s disease, along with coronary artery disease, diabetes, and even cancer.

But focusing on the brain, I think it’s important to emphasize that elevated blood sugar has wide-ranging negative effects on brain cells and their functionality. Elevated blood sugar is associated with inflammation, and this is a cornerstone mechanism across a wide spectrum of neurodegenerative conditions, including Alzheimer’s disease and Parkinson’s disease. In addition, persistent elevation of blood sugar ultimately compromises the function of the hormone insulin. We now recognize that insulin is important for the health and integrity of the brain not only because of its role in allowing glucose to be used as fuel, but also how it functions as a nurturing hormone. Continue reading

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The Empowering Neurologist – David Perlmutter, MD, and Dr. Will Cole


When Grain Brain first hit shelves, one of the first questions I started to hear repeated to me again and again was “This is great and all, but what can I do if I’m a vegetarian?” The answer is simple: you can be a vegetarian and follow the Grain Brain lifestyle, no problem (and if you want to learn more about this, visit our vegan/vegetarian focus page).

Now as similar lifestyles begin to take the spotlight, the ketogenic lifestyle chief among them, the same question, posed about these diets, are coming to the fore. Thankfully, Dr. Will Cole is here to help. Continue reading