Category: Brain Health

In this section you will find everything pertaining to the subject of brain health and preventing cognitive decline. Whether you are wondering how to prevent Alzheimer’s or what to eat when experiencing brain fog, this Brain Health section explores the connection between proper nutrition and brain preservation and development.

Some posts to get you started:
Reversing Alzheimer’s Disease
Food For Thought

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Implications of the “Alzheimer’s Gene” in Children

The development of highly accurate and widely available genome sequencing technology has put us at a crossroads. Now, more than ever, the divergent views of nature versus nurture confront consumers wishing to be advocates for their own health. As we learn about our genetics it seems quite clear that the deterministic message about our health destiny is ringing loud and clear. More and more, the idea that we are at the mercy of our inheritance seems supported by the advancing understanding and interpretation of our individual genetic profiles.

An important message we have been espousing over the past decade centers on the importance of lifestyle choices, specifically directed to offset disease risk that may well be enhanced by genetics. This ideology centers on the notion of genetic predisposition in contrast to genetic determinism. It is this contrast that opens the door to empowerment and your health destiny.

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Beyond Genetics – Our Choices Chart Our Brain’s Destiny

One of the most important goals of my life is to raise the level of awareness of the importance of lifestyle choices in determining a person’s risk for Alzheimer’s disease, a disease for which there is no meaningful medical treatment. To be sure, this narrative isn’t something that mainstream medicine fully embraces. But this isn’t necessarily a surprise as the whole notion of disease prevention still remains on the back burner as far as the world of Western medicine is concerned.

But the publications showing the powerful influence of specific lifestyle choices on Alzheimer’s risk are appearing with ever-increasing frequency in the world’s most well respected scientific publications. To that point, The Journal of the American Medical Association just published a powerful report looking at the relationship between genetic predisposition for dementia and the influence of lifestyle choices. This study begins by indicating that there are genetic risks for dementia. It then describes the focus of the research being dedicated to determining how much of the genetic risk may be offset by making specific choices in terms of things like smoking, diet, physical activity and alcohol consumption. Continue reading

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Move Your Body – Love Your Brain

How does simply moving around affect the brain? For the past several years I’ve been doing my best to get out the information that shows how aerobic exercise benefits the brain by increasing the growth of new brain cells, as well as reducing the risk for brain degeneration. However, it looks like most adults are not achieving the 150 minutes of moderate to vigorous physical activity/week recommended by the 2018 US Department of Health and Human Services (HHS) Physical Activity Guidelines. In fact, this level of physical activity is only achieved by 57% of adults aged 40-49, and a paltry 26% of those aged 60-69.

That said, researchers recently set about exploring whether simply moving around would have a beneficial impact on brain health. They designed a study of 2,354 participants (with an average age of 53) that ran for three years. The subjects wore an accelerometer that basically determined both the number of steps they took each day as well as the intensity level of their activity. Continue reading

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Benefits of Probiotics for your Mood, Gut, and Immune System

By: The Dr. Perlmutter Team

One of the most exciting developments in lifestyle science over the last decade has been the sharpening focus on the central role that our resident microbes (bacteria) play in regulating overall health. These microbes, together with their genetic material and metabolic byproducts make up what is collectively known as the microbiome. It is becoming readily apparent that the trillions of microbes living on and within us play a fundamental role in almost all of the systems of the body. Even as recently as 10-20 years ago, we did not understand the extent to which the gut microbiome can influence a person’s mood, regulate appetite, produce essential vitamins, regulate the immune system, and influence systemic inflammation.

There is even evidence to suggest that the microbiome affects us on such a fundamental level that it can regulate the expression of our DNA! Continue reading

Vitamin D and Alzheimer’s Disease: Could Deficiency Increase Your Risk?

Vitamin D and Alzheimer’s Disease: Could Deficiency Increase Your Risk?

You know, we’ve explored, several times now, the relationship between vitamin D levels and risks for severe health complications, including dementia. Notably, my colleague Dr. Dale Bredesen has written and researched much on this topic, particularly with regard to the relationship between vitamin D levels and Alzheimer’s risk. In fact, Dr. Bredesen even includes vitamin D supplementation in his protocol for treating Alzheimer’s and dementia. Continue reading

The Empowering Neurologist – David Perlmutter, MD, and Dr. Sara Gottfried

The Empowering Neurologist – David Perlmutter, MD, and Dr. Sara Gottfried


Brain Body Diet is the newest book written by New York Times best-selling author, Dr. Sara Gottfried. Dr. Gottfried writes about the uniqueness of the female brain as it relates to physical body issues, such as weight loss, as well as psychological issues like anxiety, happiness, and mindfulness. It’s a deep dive into a vast array of lifestyle opportunities that can absolutely rewrite a woman’s health destiny. Brain Body Diet is an incredibly empowering work and I can assure you that you will find this interview to be very meaningful. Continue reading

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Even Mild Exercise Helps the Brain

An important part of my lectures over the past several years has been to emphasize how our lifestyle choices, around things like sleep, diet, and exercise, will ultimately impact the destiny of our brains. For example, we have long been discussing how exercising today relates to a healthy brain in the future, especially its association with reduced risk for dementia.

Now, new data is revealing that exercise not only has long-term benefits for brain health, but even more acute changes are being discovered that are clearly positive. Continue reading

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Why DHA Remains on the Supplement List

Over the past 10 years, in the various books that I have written, there has been a persistent emphasis on the importance of DHA, an omega-3, in terms of brain health. DHA represents over 90% of all the omega-3, polyunsaturated fatty acids in the brain, and further, it’s 10 to 20% of all the brain’s fat. DHA is especially concentrated in the gray matter, and is also an important part of the cellular membrane of neurons. DHA also has an important role to play in the functioning and structure of mitochondria, the release of neurotransmitters, the expression of DNA, the creation of the myelin insulation around every neuron, the management of neuroinflammation, and even the growth and differentiation of brain cells.

DHA plays a particularly important role in the frontal lobes, allowing us to maintain executive function, pay attention to the various tasks in which we are engaged, and even plan for the future and solving problems. Continue reading

The Empowering Neurologist – David Perlmutter, MD and Dr. Lisa Mosconi

The Empowering Neurologist – David Perlmutter, MD and Dr. Lisa Mosconi

Today’s interview is with Lisa Mosconi, PhD. She is the associate director of the Alzheimer’s Prevention Clinic at Weil Cornell Medical College in New York. Prior to that she served as the director of the Nutrition and Brain Fitness Lab at New York University, School of Medicine.

Dr. Mosconi holds a dual PhD degree in neuroscience as well as nuclear medicine from the University of Florence, Italy, and is board-certified in integrative nutrition. Continue reading