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Category: Success

Dr. Perlmutter and Danielle


It’s great to hear about the success that Danielle, a patient of mine, has had, and I look forward to hearing about the results from her upcoming race. – Dr. Perlmutter

I am a 44 year old woman who has Multiple Sclerosis.  I am also a lifelong endurance athlete, having competed in events ranging from ultra marathons to Ironman triathlons. There is no question in my mind that the high-fat, low carb diet that Dr. Perlmutter has placed me on has improved my health tremendously.

For as long as I can remember, I have suffered from stomach aches and wrapping pain around my midsection. I endured years of emergency room and gastroenterology visits/tests before receiving a diagnosis of MS. My doctor at that time encouraged me to take the disease-modifying medications, but I was repelled by the side effects of these meds and began to research alternative therapies. A friend suggested that I see Dr. Perlmutter and I will forever be thankful for that recommendation.

Dr Perlmutter placed me on a high-fat, low-carb diet, like the one identified in Grain Brain, and revamped my arsenal of supplements. Within a week I was feeling amazing and the stomach aches and pain around my midsection had disappeared. Additionally, I have more energy, and my joints feel more lubricated (even the tendinitis/bursitis that has long affected my right knee has disappeared).

As an endurance athlete, the freedom from relying primarily on glucose as fuel has been tremendous. After a brief period of adaptation (about two months in my case), I have trained my body to use fat for fuel rather than glucose. I can now go out and run for hours (at around 70% of maximum heart rate) with only a bottle of water and without the numerous gels that I used to ingest.

Last year I completed a six-day, 156-mile race across the Sahara Desert. The race required self-sufficiency, so I had to run with a pack containing everything that I needed for survival over the six days (except water, which was distributed about every 8 miles). At that time, I was a carb junkie and my pack was filled with sugary gels and snacks. As the intense heat, rough terrain and successive daily efforts broke my body down though, I became nauseated by sugar and dreamed of bacon dripping with grease. This is absolute confirmation to me that my body craves and prefers to run on fat!

I am excited to return to that race again this year armed with the knowledge that Dr. Perlmutter has given to me. This year my pack will contain nuts, grass-fed beef jerky and packets of coconut oil. A lighter pack translates to an easier and hopefully faster race.

Thanks Dr. Perlmutter!


You can learn more about Danielle and her story by visiting her website.

  • Lynn Dell

    Way to go! You inspire me! I used to run, and when more weight gets off I would like to get back into it!

    • David Perlmutter

      Great plan Lynn. Running is a fantastic way to exercise.

  • Theresa Carlson-Christensen

    This is VERY encouraging! I have be
    en diagnosed recently with MS and have changed my diet to gluten free and I feel better. This now makes me want to pursue the GRAIN BRAIN way. High fat, low carb way. Your truly are inspiring!

    • David Perlmutter

      Glad you can draw inspiration from this Theresa. That’s why I share these stories.

  • Michelle White

    Hello- I have just been diagnosed with MS- and am still learning about it, and specially with medications. I would be interested in any more info out there on on treatment and if there is any scientific evidence of grain free diets helping, and risks of using that instead of disease modifying drugs. I have been gluten free (but eating “non-gluten” substitutes for about a year) and this is the first time I have had an issue that has left me with mobility problems. I am looking at grain free diets and slowly making a switch as I have grown up having a large volume of the diet having grains in it. Any info that has documentation would be helpful on this so that I can have a more intelligent conversation with my neurologist when I next see him. (After 3 days of IV steroids, I am improving in mobility.)

  • Keena Meadows

    Kudos to be a physcian that is willing to think “out of the box”. I was diagnosed 9 years ago and I am an endurance athlete as well. Just finished Ironman Arizona in November. I took medication the first year I was diagnosed and hated how I felt. Since then I have been on no medication, eat healthy and have a neurologist that supports me 100%. Love to see stories like this!

  • Phil

    I’m a 62 year old man and in fairly good health. I’m reading Grain Brain currently having recently finished Wheat Belly. I’m on board with the anti wheat/glutin message (and down 40lbs. as a result) one question about your book. The chart on p. 76 shows walnut oil to be higher in Omega-6 than Omega-3 which seems counter to what you say on p. 74 about olive, flaxseed & walnut oils being good as they are rich in omega-3, could the values on the chart have been reversed? Thanks for your great work. By my weight loss I have become an ambassador for your book whenever I’m asked, how did you do it?

  • Johnson

    There is something missing on the value of nuts. They are a good food, but they have plenty of omega 6. The omega 3 they have are not worthy, as it is omega 3 ALA. Apart from that, GrainBrain is a wonderful book.

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