Category: Grain Brain

Grain Brain and the 7 Super Supplements

A brain-healthy, Alzheimer’s-fighting diet has properties that extend far beyond just decreasing your daily carb load. To truly provide your body with brain-boosting nutrients and vitamins that help stave off brain disease and other illnesses, you should consider a regular regimen of supplements. These seven supplements will go a long way towards helping you with prevention:

  1. DHA: An omega-3 fatty acid that represents more than 50% of the omega-3 fatty acids in the brain. Numerous studies link high levels of DHA with a decreased risk for dementia, Alzheimer’s and other brain diseases (view some of these studies here on my site). Look to take in about 1,000mg/day.
  2. Resveratrol: If you like that red wine is permissible in the Grain Brain lifestyle, then you can thank this natural compound which slows down the aging process, boosts blood flow to the brain, and promotes heart health. In addition to the role it plays in stimulating brain function, resveratrol is also a key ally of our body’s immune system. Target 100mg twice daily.
  3. Turmeric: If you follow me on social media (Facebook, Twitter), then you’ve heard me talk about turmeric before. Turmeric is well known for its anti-inflammatory and antioxidant properties. We can thank turmeric for protecting our mitochondria (thanks to its role in stimulating antioxidant properties), and it also improves glucose metabolism — both of which are essential for reducing one’s risk for brain disease. Try to get 350 mg twice daily.
  4. Probiotics: Research conducted in just the last few years has started to conclude that eating food rich in probiotics can influence brain behavior, and may modulate the effects of stress, anxiety, and depression. In Grain Brain, I dive deeper into the relationship between probiotics and brain health, and today’s researchers are further exploring the role gut bacteria may play in maladies ranging from chronic pain to autism. Ideally, get your probiotics through a supplement that contains at least 10 billion active cultures from at least ten different strains, including lactobaccilus acidophilus and bifidobacterium.
  5. Coconut Oil: If you follow this blog, you know I am a big fan of coconut oil and probably know why it’s an important part of our diet. It’s even a part of my anti-Alzheimer’s trio! Go for at least 1-2 tablespoons of an organic variety daily.
  6. Alpha-lipoic Acid: Alpha-lipoic acid is a powerful antioxidant that works to protect brain and nerve tissue. Look to get 600 mg/day.
  7. Vitamin D: I can’t say enough about the importance of Vitamin D, and that’s why I devote five pages to it in Grain Brain. To learn more, watch my video on the subject. It’s ideal to start with 5,000 units of Vitamin D3 daily, get tested after three months, and adjust accordingly.

As with any dietary/health changes, these are suggested guidelines only, and you should consult with your physician before making any changes to, or beginning, a supplement plan.

For more information, order your copy of Grain Brain today and join Dr. Perlmutter’s email list.

  • Paleo

    Can you recommend the recommended manufacturers as stated in your book? I have been unable to find this on your website.

    • David Perlmutter

      Stay tuned, we’ll be launching a supplements section on the site in the near future. It’ll be announced via email and social media.

      • Tippy Girl

        Your book was released in 9/13 and you stated you’d provide recommended manufactures. Here it is almost 12/13 and we are still waiting…come on really.

        • Karen Ferguson

          chuckle…the guy’s gotta sleep in order to “walk the talk” for heavens sake. I know of NO other website where the doc participates in the blog discussion. There are probably a few, but I don’t know them. Too risky to put oneself out there, I suspect.
          I can’t imagine this participation to last much longer: I prefer it over listing the manufacturers: he can list them but can’t possibly monitor them a year later: that research we should be doing on our own. The company could be sold and the protocol changed for the worse. My 2 cents.

          • Antonio Reynolds

            @disqus_B2K6wjFeLc:disqus…that’s worth more than 2cents!!!!!!..Dr. has cracked the door for us, now we need to take some responsibility for our own health & walk through the door!!!!

          • Karen Ferguson

            I so agree!! I feel empowered!!

          • BH

            Dr Perlmutter
            Please advise where can I get the
            starter culture for sauerkraut as you suggested in one of the online article:


          • Dori

            Katz has two wonderful books on Fermentation. I’ve found that when I add one probiotic capsule along with the salt to my shredded cabbage every batch turns out great and it’s ready for the refrigerator within about 3 days. A “starter” isn’t really needed. Using the probiotic is more consistent than trying for “wild” organisms to get the batch going. Hope this helps.

          • Thomas

            To get the full benefit of all the probiotic goodness you need to ferment for four weeks. Research it further. You need no starter culture at all. Use a fido jar and tuck away. They gas off and never any mold. Real, homemade sauerkraut has changed my life. I have 20 quarts fermenting and eat it every day.

      • Tom Evans

        Dear Dr. Perlmutter: Thanks for your good work. I am interested in luteolin a phytochemical found in celery, green peppers and parsley that some research indicates fights the formation of amyaloid plaques. Have you read “Alzhiemers: What if there was a cure?” by a neonatalist MD. She claims that her husband is almost cured of ALZ due to coconut oil.

        Best Wishes, Tom

  • Eric


    What are you thoughts about using MCT oil in place of coconut oil?

    • @edible_oils

      Coconut Oil has almost 50% lauric acid, which is an excellent anti-microbial. You miss out on that with MCT oil. In the work Dr. Mary Newport did regarding brain response in Alzheimer’s patients, MCT has a faster response, but coconut oil has a more sustained response. I would conjecture that’s because the medium chains convert to ketones faster, whereas the coconut oil has some long chains mixed in, therefore processing slower.

      My preference would be to coconut oil generally, because it is a whole food. Our bodies seem to like it that way.

  • Sandy Eisen

    I can understand taking supplements (or, in some cases, pharmaceuticals) to correct existing problems. But taking supplements indefinitely, as well as eating a healthful diet? Why should that be necessary? If you’re a “paleo” guy — well, did cavemen take supplements?

    • Shannon

      The food we eat today isn’t nearly as nutrient dense as the food that was available ages ago. Soil depletion, pollution, the diets of the animals we eat, etc. Mark Sisson has an article on the importance of supplements, too. He’s a great resource. http://www.marksdailyapple.com/definitive-guide-to-primal-supplementation/#axzz2lOtU10iL

      • Stephanie

        Actually, the food we eat today is far more nutrient dense than what was around 30,000 years ago–just look at broccoli, carrots, and every other plant we’ve been cultivating… That’s almost the problem–we’ve beefed up [some of] the nutrients in so many foods that we’ve lost the balance.

        • elfel

          I don’t believe that’s true, Stephanie. Why would current day plants be more nutrient dense than plants grown on soils that were not depleted of nutrients like today’s soils? To say we’ve beefed up the nutrients so much is absurd. Cultivation doesn’t mean nutrient density is increased. The only thing that has been increased is the sugar content of these plants.

          • Gravity

            Well yes, with exceptions like carrots that didn’t have nearly the beta-carotene it has today due to it being cultivated that way (they used to be more brownish, yellow,- if I remember the article I read).

    • Tom Evans

      No, and our evolutionary biology lowers immunological responses as we age and we become easily diseased and die. Supplements optimizes our biological clock and our health while we are here.

  • Art C

    How about magnesium, zinc and selenium?

    • Gayle

      I have heard that copper, iron and zinc are linked to al Alzheimer. What is your opinion?

  • Louise Gerace DePino

    What about Coconut Oil supplements? Hard to get 2 tps in hubby!

    • Jan in KW

      I’m on a wheat-free blog and a member shared the following recipe….Fat Bombs: 1 cup melted coconut oil, 1/2 cup melted pastured butter, 1/2 cup almond or cashew butter, 8 tabs. organic 87% cacoa powder, stevia or monk fruit to sweeten (if necessary)…..bring to a boil, pour into ice cube trays (3 or 4)…….freeze for 1/2 hour then put in zip lock bag.I use 4 trays and make them smaller…..it’s a great way to get some healthy fat!

      • Louise Gerace DePino

        Thanks Jan, actually sounds yummy! Going to give it a try.

      • Dee

        Make some scrambled eggs for breakfast and cook them in coconut oil. Make a curry dish and add coconut oil into the dish. I also make homemade chocolate with cacao butter, coconut oil and cacao powder. Lots of ways to add coconut oil to food.

        • Karen Ferguson

          wow…..homemade chocolate? Curry? Yum. I’m comin over for dinner…okay?!!

    • the brit

      use it in cooking, on vegetables, in soup.

    • Boo

      Try putting it on a baked sweet potato…awesome!

    • Jenn Moran

      We use it to cook eggs, veggies, and in smoothies! Easy to get a lot that way!!

  • Cliff

    Any thoughts on the benefits of Astaxanthin?

    • Kathy

      I am also interested in that issue.

      • Jamie

        Astaxanthin is supposedly great for brain health. I take 12 mg everyday.

    • Danielle Reeves

      12 mg a day sent me to the ER with severe nosebleeds..never again.

  • the brit

    I get the cholesterol, brain connection. but what causes the plaque to collect and block arteries?

    • Tom Evans

      Inflamation!!!!! See National Geographic special entitled “Stress.” The work of Dr. Salospky in that doc. shows direct relation between stress and the formation of plaque in the veins of primates. Also look at studies in psychoneuroimmunology…a new and exciting field.. Best

      • Karen Ferguson

        I adore Sapolsky’s work. He’s an instructor at Stanford. I heard him talk on AD for 8 hours w/ 4 large index cards!! What?? OMG! He’s brilliant. At that time, 7 or 8 years ago, he didn’t drink and minimized his meat intake or was vegetarian because of Cruzdtfeld-Jacob Disease [mad cow]. Grass fed beef wasn’t talked about so much then.
        Wow….thanks for reminding me. You can find him on You Tube. I love his Zebra stories. The Zebra says “What? What? You’re pissed because you got cut off on the freeway? Whadda ’bout me…my life is at stake here…runnin’ from lions and all!!” In essence, hang it up on the fight or flight response for measly reasons of being cut off on the freeway. Save it for life threatening episodes, if you must.

        • T. Evans

          Hi Karen: Have you seen the Book “Alzhiemers What if there was a cure”? By a pediatrician (forget her name). She put her husband on coconut oil after he had sever AD and had wonderful results. She does a great job explaining the mechanisms that improve the brain’s biochemical environment.

          As for inflamation and plaque there are two sudies showing that pomegaranete juice significantly reverses plaque formation.

          • Karen Ferguson

            No …haven’t seen the book but will look for it now!!
            Don’t know a thing about pomegranate juice but I’m delighted to do some searching about it. Thanks tons!!

          • NYC

            Because of Vitamin C.

    • Mary

      You’ll find that answer in the book, “Vitamin K-2 and the Calcium Paradox”, written by Kate Rheaume-Bleue

    • The Talking Magpie

      The brit,
      There is also some evidence that chemicals scar the lining of your arteries, which are one cell thick. The scarred lining causes the plaque to stick into those grooves. One such chemical is chlorine which is added to most water systems. I only drink filtered water in glass bottles.

  • ED

    Whoever is proofreading the copy for this website needs to be taken off grain

  • Mary

    Why isn’t hemp seed on the list of fabulous natural fats??!! Hempseed is a natural food, a great source of Omega 3’s and some 6’s not necessarily to be considered as just a supplement.This plant is a distant cousin of the “get high THC variety, with little to no traces of the other plant. Fabulous for brain function, joints, and all the things that chia seed does. Just another option. You can bake with it, put it into green smoothies….which is a great way to get a load of low carb high nutrient greens into your life every day!

    • G Clay

      I believe Hemp to be the greatest plant on Mother Earth. Over 30;000 things can be made from Hemp.

      • Karen Ferguson

        Me, too!! I wear hemp fabric as much as possible: beats linen hands down for sturdiness!! I just wish it was prevalent to grow it here so the hemp farmers could be assisted. On another different note, I read an article a month ago about marijuana farmers playing havoc on the environment….don’t know it first hand but will do some more research. HEMP ROCKS!!! Thanks so much for the reminder.

  • Brigid

    I put turmeric in all my savoury baking. Here is an article on its positive effects. http://www.greenmedinfo.com/blog/turmeric-wellness-promoting-tonic-low-doses-research-reveals01

  • CaliJen

    Is there a way to know if turmeric has added fillers? It is cheaper at ethnic stores and claims to be pure turmeric. Is there a simple test we can do? or better still is there a consumer protection lab we could send a sample to see if it has added wheat flour? I would like to expose false labeling and packaging that could be hurting people.

    • Maryann

      Hi! Consumerlabs.com does the quality assurance testing you are seeking. They recently tested curcumin.

    • Liz

      My naturopath (at Bastyr Clinic in Seattle) recomended Curcumax Pro. I get it locally, but I believe it’s available at Amazon.

  • Mary Petti

    What can you take in stead of coconut oil? I react to all tree fruit.

    • risantos

      MCT oil

  • Tabia

    Ann Wigmore training has exposed me to a fermented drink call Rejuvelac which is made with soaked and sprouted spring wheat( organic, non-GMO). Her colleague Harvey Lisle (hope spelled correctly) is said to have analyzed this drink and could call it a probiotic. Do you have familiarity with or a position on this drink (besides the fact that it takes lots of getting use to)?
    Thank You. Appreciate you, your work, and getting the message out.

  • Ryan

    Hi Dr.,

    Can you suggest a brand of Probiotics as I am having trouble finding one with at “least 10 billion active cultures from at least ten different strains”?

    Thanks for all your work and info.

    • Donna Brehler

      Hello Ryan, check out the line of probiotics from Renew Life. http://www.renewlife.com/. Great product and not that expensive.

      • Halle Lu Ya

        I take a very expensive one – which is actually a living food – VSL #3 recommended years ago by my GI doc for folks with colitis and irritable bowel. Not everyone has to take it but it works for me.

        • christal

          I take the same and it’s fantastic. there is no price that can be put on the value of probiotics for keeping us healthy. I ,also, make yogurt from the Specific Carbohydrate Diet. It’s easy and loaded with the good bacteria we need. An important part of my regime.

      • Ryan

        Thanks so much Donna, appreciate the help!

      • David

        check out Qhnshop.com no binder or filler in any product clean!

    • Laila Grace

      VSL#3 is the best Probiotic I have found. I had IBS in the worst way for years. Since following this lifestyle it is gone but I still take the probiotic. Your Dr can prescribe it of order online. Amazon is a good place to order it and make sure they ship it in dry ice. Must be refridgerated.

    • teri

      Hi Ryan, Look for Vitamin shoppe brand.

    • susan

      Ryan, They have a few different ones at wal-mart and stop and shop that have 10/20 10/25 10/30. $15.00-$20.00 for 30 day supply

    • David

      go to Dr. Bob Marshall site qnlabs.com and for better information the same company QNHSHOP.COM THESE VITAMIN AND MINERAL DO NOT HAVE FILLER OR BLINDER.

    • Thomas

      I make my own fermented foods. I make sauerkraut and yogurt mostly. Kombucha does not work for me. I am simply amazed at the delta my gut has made. Albeit, sauerkraut has to be from a homemade source and not grocery shelved. Live foods are awesome and has saved my life.

      • Thomas

        I should have stated that I make my own coconut milk yogurt.

        • Truth59

          Could you email me your recipe for coconut milk yogurt? Do you use a yogurt maker? Do you have to use fresh milk from a coconut too?

          • SunnySky

            Same here on the coconut milk yogurt. Or post here, please. Thank you!

        • Jean

          @Thomas where do I get the recipe for coconut milk yogurt?

      • Sandy

        How about Bubbies brand sauerkraut at Whole Foods?

        • Thomas

          Hi Sandy. I’ve read that this product is good with active cultures but no personal knowledge. I’ve seen local kraut at a particular organic store also tht only does locally produced product. like making my own though.

          • gaylep

            Hi Thomas, Would you share how you make your sauerkraut and yogurt? Is it time-consuming? Thank you for your thoughts!

    • Victoria Bennett

      Try whole foods. They are great in helping.

    • paulap

      mercola makes a really good 1…90 billion i believe….mail order….amazon.com

    • Susan Stephen


      These are the best I have come across so far. You can buy them at http://www.mydoterra.com/susanstephen/ if you like…

    • StarsAndStripes

      I am making my own Kefir which has lots more probiotics than the commercially available kind. I don’t know if this is allowed, but here is where I got my start: http://www.culturedfoodlife.com/

      • Elói Ângelo

        I am waiting for a donation of kefir next week (milk type). Lets see if i can make it grow. I believe this is good enough. What do you think?

        • StarsAndStripes

          I’m not sure I know what you mean when you ask ‘is this good enough’. Home made kefir has lots more probiotics than the store bought variety has. So, yes, that is good enough for me!

  • Sue

    Dr. Perlmutter: Do you recommend these supplements for pre-teens and teens? If so, is the dosage the same? Thank you.

  • Marsha

    Why isn’t tuna allowed on the diet? I live on island off the coast of MA and we get a lot of fresh tuna. I know if tuna is not eaten the same day it is processed in some way that is not healthful. Can someone respond to this? Thanks

    • Jamie

      It could be the mercury content? Not sure though.

  • kathie

    What is the most healthful brand of supplements that does not include silicon dioxide or titanium dioxide?

  • Pat

    Hi Dr. Perlmutter, I was wondering your thoughts on osteoporosis, I was on Forteo injectons for two years, now on Fosomax for two to three years and have low Vitamin D. I am currently taking 5000 per day. What are your thoughts on Fosomax and should I be increasing the D? Also I read an article that eating three dried plums a day works as well as medication. I appreciate any comments. Thank you, Pat

  • Patricia Fenn

    I have almost finished your book, and I am going to read it again. I am 82 years old and I really want to prop up my brain. I have suffered with celiac problems all my life, and have been off gluten for 20 years. It was finally diagnosed when part of my large intestine was removed. My immune system was not effective for most of my life, but when I cut out gluten that changed. I play tennis, run, and go to the gym. My health is great and I have no health problems. I know no one my age with better health. I had not suffered with any of the health problems you list on page 10 & 11 in your book except for intestinal problems and being tired when gluten was in my system. These problems were extreme. I am a high achiever and still working as a fine art artist. My four children have been self employed most of their lives.

    My memory is not as good as I would want it to be. So, I will work very hard with your book in hand to solve this problem.

  • Roben

    Dr. Perlmutter, I have been gluten free now 30 days. My eye is still twitching and has been about 4 years. Anymore recommendations? Please

  • Mike

    Dr. Perlmutter,
    You said that cholesterol is good for our brain. Should I stop taking a statin to reduce my cholesterol level?

    • David Perlmutter

      Mike: While I can’t consult on what you should do, and you should speak to a doctor before making any changes to your diet or medication routines, I will point you to these two articles I have authored on the subject of statins:

      1) http://www.mindbodygreen.com/0-11703/what-the-new-statin-guidelines-mean-for-you.html

      2) http://www.mindbodygreen.com/0-11056/what-you-need-to-know-about-statins.html

      • Jack Goldman

        I am curious if we are related, my paternal Grandmother’s family who settled in Ohio were named Perlmutter. My father’s name was David Goldman.

    • The Talking Magpie

      I have a friend that has permanent muscle damage from taking statin drugs. Go to the bookstore and find a drug manual for nursing students. Look up atorvastatin which is the generic name for Lipitor. Be sure to read the adverse affects, some of which you will need to check online to see what they mean – like rhabdomyolysis. My friend did not experience muscle pain until his doctor upped the dose because his cholesterol was getting any lower after 2 years on the drug. No one can tell you what to do. Do the research.

    • 50Marie_Flowers50

      Dr. Steven Sinatra, a holistic cardiologist who refers to himself as a Metabolic cardiologist, has recommendations on statin drugs. He said there has been a 600% increase in congestive heart failure due to statin drugs.


  • Pingback: The Awesome and Amazing Alpha-Lipoic Acid | David Perlmutter M.D.()

  • Diona

    What do you know about Restless Leg Syndrome, causes and treatment?

    • Boo

      Check out magnesium and restless leg syndrome :O)

    • Name

      Magnesium and Potassium supplements stopped my Restless Leg Syndrome dead in its tracks. I don’t go a day without it.

      • teri paradiso

        What brand and how much of each? Thanks

        • kathi

          I take “Calm” magnesium powder every nite. you can adjust the amount ..”to bowel tolerance”….it is awesome

          • cazma

            I totally agree. Especially the magnesium. I had RLS really bad until I started taking Mag. If I go a week without it it starts coming back!

          • Gravity

            My RLS was tied to low iron, when I got it while my kiddos were young and I was nursing and menstrating. When I got it, I would smell my iron tabs (“whole food”, or regular iron) and sure enough, it would smell sweet and good to me!! (At other times, it would smell just like iron – metallic sort of).

      • Flokaiser

        I rub magnesium oil on my legs.

    • shirleycolee

      This may sound crazy or silly, but it works great for my husband. We read about it in the Palm Beach Post, the column called “The People’s Pharmacist”. Put a bar of soap at the foot of the bed under your sheet. Hope it works for you as it did for him if you decide to try it.

  • juan

    Dr. Perlmutter,

    I am a male 57 years old and would like to get a blood test. But I am no sure which tests would be recommended for me. I am following your recommended diet good cholesterol and exercise. I do not have any excisting health issues.

  • “Needing to know”

    Great inspiring information Dr. Perlmutter…Can you give me a little clue as to just what your diet can do to clean plaque from a persons veins and arteries? I had a TIA in 2009 which was caused by a small artery blockage in the back of my head which caused me to lose my balance for 3-5 minutes (fortunately, no damage, and no additional occurrences have taken place) Will the diet or should the diet and supplements you’re recommending aide in removing plaque from a persons arteries?????


      Do a search, ” pomegranate carotid stenosis 3 year study” from NIH.GOV and you will see 1 ounce of pomegranate juice (Pom Wonderful is used in these studies – I have no affiliation with anybody-I am retired) reduced intima media thickness by up to 30% in one year. Other than pomegranate…Alpha Lipoic acid and Serrapeptase will help with arterial plaque. After using those for a couple months you might try Vinpocetine 10 mg twice a day, morning and 8 hours later, if needed for improved cognitive function and blood flow to and IN the brain. Research these supplements and I am sure they will help you, if there is no restriction on their use you. Check with your doctor AFTER printing the research on each supplement for his approval. If he doesn’t have the time for this approach, find another doctor 🙂

    • Elsie

      needing to know

      try NEO40 daily, from neogenesis labs, or visit http://www.neogenesis.com for more info, worked for me daily heart and circulation formula me, Used it since Feb 2013. Got the name from the book MIracles from the Vault – HSI

    • Hi Needing to know, I use Pule-8 which features pharmaceutical-grade L-arginine, specially formulated in specific ratios to provide optimal results helping in control blood pressure and cleans arterial plaque formation in the veins and arteries. It’s sold here http://vestedcare.farmersmarketproducts.com/#/pulse8. Another good resource is http://www.1855MyKetopia.com.

      • Eddie Garza

        hi 1855MyKetopia, hope you are doing well. Have you seen any improvement while using the Pule-8? Thanks

    • Tony Porta


      There is a study on pomegranate literally cleaning athlersclerotic plaque from in endoltheial lining of the blood vessels. The study showed, without dietary modification and just the addition of pomegranate extract twice daily resulted in a 33% reduction in arterial plaque in just one year.

      Dean Ornish is a physician who advocates for a whole food plant based diet (vegan). He has worked with the most severe heart disease patients and turned their heart disease around completely. He used an angiogram, which measured blood flow through blood vessels. After dietary intervention coronary blood flow restored and arterial plaque dissolved. I caution you, do not resort to vegan cakes and donuts, the basis of his diet is low glycemic vegan based on whole plant foods.

      • Eddie Garza

        Hi Tony, thank you for posting. How many milligrams per day per serving does he recommend? Thanks.

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  • Ron

    Guidance on wheat and gluten free bread?

  • Halle Lu Ya

    What should one use to bring down A1C (prediabetes), FBG and also improve EFGR (all other labs WNL).

  • Chloe’s grandad


  • Gayle

    I have read that copper, iron and zinc are linked to Alzheimer’s, what is your opinion?

  • Carlo

    Is there a direct correlation between the amount of gluten consumed or is there a threshold?

  • cody

    What do you do if you don’t tolerate coconut oil, fish oil, tumeric, and other anti inflammatory foods. I am allergic to NSAIDs and have wondered if it is because I metabolize things differently so even natural cox-1,2 inhibitors are not tolerated. They make me swell with angioedema and chest tightness.

  • Margaret Lindop

    Please clarify the amount of DHA., as recommended in Grain Brain.
    In, Chapt. 7.(p. 223, Kindle). 200 mg./daily is recommended for children
    older than 18 months.(or 400 if they have ADHD) I assume that holds for
    adults, too? But -in the supplement listing that follows-the DHA dosage is 1,000mg daily. Which is correct? Thanks! Margaret L.

    • David Perlmutter

      Hi Margaret: Thanks for the question. If you flip just one page, you’ll see a rundown of my supplement listing (pg. 224 in the hardcover) which notes my 1000mg recommendation.

  • Walt

    Dr. Perlmutter, I have really enjoyed reading your book and plan to incorporate what you teach as it makes sense. But I have a question. In the book, The China Study, the research they present over 30 years indicated that people who don’t eat very many animal products have almost no cancer or heart disease and the people who do eat animal products on a regular basis do have more cancer and heart disease. Can you help me understand this study and why it is contrary to the research in your book.

    • Chas

      I have the same question as Walt

  • Jen

    You state in Grain Brain that you have a list of some of your favorite supplement brands on your website, but I can’t find it. Please help.

    • David Perlmutter

      Jen: Thanks for staying on top of me about this. Very shortly, we’ll be launching the supplements section of the website.

      • Dori Lewis

        I see this was 4 months ago. When is shortly?

      • dispo

        When is shortly?

  • Marnie McCallister

    I can’t thank you enough for your tremendous book Grain Brain, Dr. Perlmutter. It must be a fantastic feeling, knowing you are changing so many lives for the better. I got serious about changing my nutrition last January, and the difference has been amazing. I look better, but more importantly (much more), I feel so much better.

    I know you can’t comment on every study that comes out, but I think it would make an interesting blog post if you would talk about this article (and study) to show just how easy it is for the media and researchers to slant their findings, and see what they want to see–


    Anyway, thanks so much for everything you are doing to educate people on the simple ways to improve their health and protect their brains.

  • Maggie

    Dr do you have an opinion on Autism and diet

  • Jcf

    I’m still nursing my 14 month old. Can I still follow your advice as is? My husband and I loved your book – he’s an ortho surgeon. Cheers!

  • sharon

    Dear Dr. permitted,
    My son is 20 and was diagnosed with adhd/pdd when he was 3. He was on Ritalin and then Concerta and after going through side effects took him off. My son will eat whole wheat bread with peanut butter with sliced apple almost every day for breakfast with milk and I told him you can’t have that every morning it’s not good. He also has very big bowel movements and I believe it has to do with him being gluten sensitive. I want him to have a blood test to see. Any advice would be appreciated. Thank you.

  • sharon

    From sharon: I’m sorry that I misspelled your name Dr. P. For some reason when I typed your name it came out as Dr. Permitted.

  • Ruth Zalph

    Please list the vitamins rec. for a fish eating vegetarian, not overweight & 83, healthy woman wanting to ward off alzheimers

  • The Talking Magpie

    I was amazed that after 4 days on the protocol my fasting blood sugar went from 100 to 79. My last A1C was 5.8, but I could never get my fasting blood sugar any lower than 100.

  • saddLLP

    I just finish your book in audio format and haven’t had a grain in several days. My father is having some serious health issues (78yo). He had his gall bladder removed, got pneumonia and due to the (lack of) care, has lost 25 pounds, he pneumonia has returned and he is not getting stronger. Long, long story short, he was diagnosed with hypothyroidism and they have put him on synthoid. The problem is that they are feeding him a ‘heart health’ diet and limiting him to a cup of water a day due to low sodium. Am I wrong that this high carb/.low fat diet is not going to make him gain weight and get strong? Also, I understand that the low sodium is likely a result of the hypothyroidism? Seems like he would benefit from was electrolyte and calorie rich beverages so he can get strong? I understand you cannot tell me not to do what his doctors believe to be correct, but what would you do?

  • Kathleen Alzheimer

    Hi Dr. Where do I find the list of your favorite brands of these supplements? Thank you.

  • Nanette Sorensen

    Have you heard of Omega XL which contains natural green lipped mussel oil extract? I’d like to know your comments on it. Developed in New Zealand.

  • David Benoit

    Just an F.Y.I. I went to the local EarthFare armed with my list of “Seven Super Supplements” and based on the recommended dosages I calculated that it would cost a minimum of $100.00/month to take all of them. And again that is just a minimum. Hard to swallow. No pun intended.

  • K2

    I am a vegetarian and rely heavily on my carbs to eat and get my protein. How do you eat a high-fat gluten-free diet? Dr Perlmutter, you don’t address this in your book. Could you share some recommendations?

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  • agreekgrl

    Can you take the coconut oil in pill form rather than out of the jar?

  • Guest

    Dr Perlmutter, can one take the coconut oil in pill form rather than cooking w/the oil?

  • Arg

    Dr, can one take the coconut oil in pill form rather than cooking w/the oil?

  • Sheri

    I am a little confused on the cholesterol issue. My husbands cholesterol levels were high while he was eating poorly. Since starting his gluten, and sugar free diet, his numbers have come way down. Isn’t high cholesterol supposed to be good according to your research? How do you make your numbers go back up while not eating sugar or gluten?
    Thank you for your time.

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  • IslandGal52

    I read on another homeopathic website that taking alpha-lipoic-acid is dangerous if you have mercury amalgam fillings. Any truth to that??

  • Maryann

    Dr. Perlmutter, thank you for all you are doing to change the world and save lives. Are any of these supplements contraindicated with the use of Crestor, Niaspan, Zetia, Glumetza or Blood pressure medications please? God bless you, Maryann

  • Tim

    Can anyone comment as to whether a multi vitamin should be taken in addition to the suggested supplements in the book.


    • David Perlmutter

      Tim: Good question. In general, I comment in Grain Brain that a generic multivitamin cannot cover up for poor eating habits. It’s not a silver bullet. They can be an incredibly useful adjunct to an already healthy diet, but never ever a substitute.

      That said, please be sure to consult your doctor before making any changes to your supplement regimen.

      • Elaine

        Is a calcium supplement recommended in addition to the diet and other supplements?

  • Pat

    Is there a good sugar substitute? how about stevia?

    • David


    • Guest

      Stevia made me sick. Don’t know why.

      • Katie

        stevia gave me a bad sore throats for months until I finally figured out it was the stevia I was adding to my coffee. Spent tons of money on an ENT doctor to no avail. After stopping the stevia the sore throat went away almost immediately. Must be allergic to it but was totally unaware.

        • Guest

          I got sick on stevia too. Was not using very much but had dizzy spells. Ended up have a brain MRI – brain is fine. I think more people that have stevia problems should speak up about it.

          • Cynthia

            That’s interesting about Stevia giving you dizzy spells. I recently had some dizzy spells, had a brain MRI (normal) but never associated it with my consumption of Stevia. I’ll have to monitor my intake in the future. Thanks for the comment!

    • Lorelle Hatcher

      I use organic agave but in small amounts. I’ve learned not to eat anything that is extremely sweet, including my tea. The transition from “Southern Sweet Tea” was rough, but now I don’t miss it.

      • sue

        Agave is so bad.. Highly processed and heated.. Organic makes no difference with this one.. switch to an alcohol sweetner or stevia..

        • Lorelle Hatcher

          The small amount I consume doesn’t concern me. Besides, stevia doesn’t dissolve well in cold liquids, and even when using tiny amounts I have a terrible aftertaste in my mouth until I brush my teeth. I’ll stick with the agave.

  • Amit

    many thanks due to this great info. their good you just read this kind of, you should stop by each of our principal web page http://www.southchicagoveins.com/ pertaining to data.

  • Linnyjane

    Since I’ve been eating this diet, two weeks or so, I have struggled with FBG readings in 120 range or more and ear aches and soar throats (a weakness of mine) and today diarrhea and sick stomach. Is this normal to begin with?

  • Becky

    Hi Dr. Perlmutter,

    I read
    your “Grain Brain” after it came highly recommend and I couldn’t put it
    down. It is amazing the amount of
    science you included to help people truly understand what happens when they
    eat. I am a small, active, generally
    healthy person, who ended up with food sensitivities, mild excema, and gluten
    intolerance. By the time I read your
    book, I already was following a paleo diet to eliminate these problems, but
    eating a lot of fruit and still thought fat was bad. I cut out most of it, and continued to read
    about starches and have figured out how much I need and when to have it. I also have worked on getting more (good)
    fats into my diet—and it’s been yummy.
    Because your (and the paleo diet in general) is so radical and causes us
    to reverse our ingrained low-fat/low meat way of thinking, I am being cautious and want
    to make sure it truly is the healthiest way for me to eat. Your book also made me think a lot about food
    and wonder, and I eat a lot of non-mainstream foods that you didn’t discuss. As a result, I have a quite a few questions
    for you, so I can feel more sure of how I am eating.

    1) Why do you allow hummus, when you rule out legumes?

    2) How far would you have to sprout a seed or
    legume so that it is safe on your diet?
    (For example a broccoli sprout has no seed left and is a baby plant.)

    3) You don’t refer to the paleo diet, but do refer
    to our ancient ancestors. You also rule
    out legumes, but it seems more for their carb content. Do you think that the lectins in legumes are
    harmful? Does fermenting, soaking,
    and/or sprouting legumes remove the lectins?
    In small amounts, can they be eaten, just as small amounts of safe
    starches like white rice and sweet potatoes?
    (My motivation for eating them is to eat as wide a variety of food as

    4) I’ve seen palm oil listed as a good fat. Do you agree?

    5) What are good sources of cholesterol?

    6) What would you recommend for breakfast for
    someone who doesn’t like (and is currently sensitive to) eggs?

    7) Do coconut and cashew milk, yogurt, and cheese
    fit into your diet? (I make them at home
    with just the nuts, water, and probiotic.)

    8) Neither you nor any paleo site I’ve read so far
    mentions salt. What is a safe amount of
    salt to have? I once read that cavemen
    did not eat salt, which I’m sure means they had no salt shaker. However, shellfish, for one is naturally
    salty, as I’m sure are some other foods.

    9) You recommend eggs for breakfast nearly every
    day. Are you concerned with developing
    food sensitivities due to repeated regular bombardment of the system by one

    10) I’m
    surprised about the cholesterol-brain power connection. I can think of two groups of people that
    might challenge this. A: smart people who have followed health
    guidelines their whole lives, most of which would say to eat low
    fat/cholesterol and B: less educated/less
    smart people who don’t care or know and eat junk, including fat/cholesterol
    (and probably bad fats, with a lot of carbs).
    So, how do people with high cholesterol score better on tests of brain

    11) Can you
    please create a food pyramid, or other diagram, that includes all the foods we
    should be eating to give us a better idea of how to proportion things out?

    12) What
    about other nut oils, such as walnut, hazelnut, avocado, almond?

    13) Does
    olive oil oxidize when heated? Is it
    better to use it raw only?

    14) Is
    there a range of carbs, fats, proteins that people need based on their activity

    15) Does
    using the carbs you eat right away (either before exercise or by replacing them
    after exercise) tax the insulin system the way you’ve described, or is it only
    a problem when the carbs are in excess of what you need? Also, does eating a whole lot extra just for
    the purposes of extreme exercise (such as a marathon) tax the body?

    16) What is
    the best food type for quick energy?
    Either for just before exercise or if you are really hungry and need
    food asap?

    17) I have
    seen several lists of sugar quantity of fruits.
    There is often a discrepancy as to which ones are least sugary and most safe
    (except for berries; they always come out on top). Can you explain this, and list the fruits you
    most recommend?

    18) What
    foods do you recommend after a stomach flu, or otherwise compromised
    belly? Are a lot of plain starchy foods
    OK then?

    19) How do
    you feel about chia, flax, and hemp seeds?

    20) How can
    a person tell if they have had too much fat or too much protein? (I’m assuming too little would make one
    hungry.) Is there such a thing as too

    21) You recommend
    occasional wine. What about other
    alcoholic drinks that are gluten-free, such as cider, mead, tequila, and rum?

    22) If
    headaches are caused by inflammation, would eating anti-inflammatory foods such
    as ginger and turmeric reduce the headache?

    23) What do
    you think of The Starch Solution? It makes the same health claims you do, but
    with a nearly opposite diet (except that they recommend all real food). (I did read their website and found little
    science backing it up, and noticed they are selling a class, so they have a
    motivation to push something that may not be good.)

    24) Dr.
    Fuhrman pushes a vegan or at least low meat diet, very often citing problems
    with eating meat. He seems to be
    thriving on a vegan diet. Do you feel
    some people can tolerate this, or is this bad for all people? Or, do you think they can tolerate it for the
    present but will have long term health problems, especially a risk for Alzheimer’s? Is there a way to get the fats you need and
    be vegan? (Mind you, I have no interest
    in it; I love meat too much and am hungry when I don’t eat it.) It’s just amazing to me the number of
    contradictory (and seemingly well-backed) health claims there are out there.

    25) You
    talk about the brain benefits to fasting and following a low car/high fat
    diet. Do you need to do both to get the
    benefits? Are there people (ie women,
    already small people) who should not fast?

    And finally, the most important consideration of

    Is there any harm or risk to following your
    diet (or something similar)?

    Are there any nutrients that are lacking?

    Could it risk damaging another organ or system,
    while it’s helping the brain?

    I was wondering about the concerns with animal
    protein, but recently read that balancing the acid of the protein with the
    alkali of veggies eliminates that problem.
    Are there any other issues with animal protein?

    Can the Earth feed healthy meat to all its inhabitants

    Can people on a low budget follow your diet?

  • Katie

    It would be great if you could develop a supplement which contains the six super supplements mentioned above (coconut oil is fine from the jar). Capsules and powder form (for adding to green juices/protein drinks) would give everyone a choice. I imagine with the growing interest the product would literally fly off the shelf!

  • Elizabeth

    Dr. Perlmutter,

    At age 9, my son was given a possible diagnosis of PANDAS when he presented with a tic of the head and neck. The tic went away after a few months with only occasional, short recurrences. Now, at age 14, we have found that he has an extremely low total cholesterol of 84. He increased his egg consumption but his total cholesterol did not increase. Could the two be related and could a gluten free diet actually increase his cholesterol? I am a few pages into Grain Brain and I am excited to learn more!
    Thank you!

  • stacy

    Hi: I am confused I read the better Brain first and now the grain brain. Which supplements should I use? the ones in Better Brain or grain brain??? They are very different. thanks

  • Matt

    Dear Dr Perlmutter,
    Greetings from Luxembourg. After reading ‘Grain Brain’ I also recently read ‘The Better Brain Book’ and about this I have a question: would you still recommend the same supplements as you did then (10 years ago)? Above you talk about 7 super supplements. How do they relate to your recommendations in ‘The better Brain Book’? I started with tier 2 (except for phosphatidylserine, which I couldn’t find) and I really have the impression my brain function is improving. Anyway, with today’s knowledge, would you say there are different/better supplements to take? Like taking uniquinol over co-enzyme Q10 for instance (see http://articles.mercola.com/sites/articles/archive/2013/11/03/coq10-vs-ubiquinol.aspx)? I was already taking 25 mcg of vitamin D daily and I try to use turmeric daily (in combination with olive oil and black pepper). Plus a daily glass of red wine and cooking with coconut oil. Anyway, thanks in advance for your reply!

  • Bruce

    Just wondering how Dr. Perlmutter feels about drinking alkaline water – which proposers suggest reduces acidic disease in the body….

  • James Smith

    Where can I find a supplement that has 1,000 mg of DHA?

  • arwen_in_nj

    does anyone know if there is a “cheat sheet” available that I can print out and keep with my vitamins to remind me of how much I should be taking and when (empty stomach vs with food etc.)?

  • candice

    Dear Dr Perlmutter,
    I just finished reading your book and found it very interesting. I have read that probiotics are not very effective in pill form and best taken in food; yogurt, kimchi, sauerkrat. What are your thought on that?
    I am also wondering couldn’t I just sprinkle actual ground tumeric on my food daily as opposed to buying a supplement and gain the same benefits?

  • Nadine

    In your book you admonish us to check out your site for brand recommendations (for the supplements)
    , I seem to be having trouble locating that page, where should I look?

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  • 50Marie_Flowers50

    There are some who have become mercury poisoned from their silver amalgam dental fillings who have suffered severe brain inflammation (burning brain) while taking alpha lipoic acid while still having the mercury fillings still in their mouths.

    Kristen Homme, is in the process now of writing an article on alpha lipoic acid to be published in a peer reviewed journal, about how alpha lipoic acid can harm brains when one has amalgam fillings still in their mouths, if taken long term. I realize there are no holistic doctors at the present who are writing about this.

    Homme recently had an article “New science challenges old notion that mercury dental amalgam is safe” published.


    You can download the complete article on Springerlink on the link above.

    People may have less problems if they take the lipoic acid in the R+ form. (R+ lipoic acid.) This may be something that Dr. Perlmutter could take a closer look at, though I do not know if there is any peer reviewed literature on this at the present time.

    DAMS, Dental Amalgam Mercury Solutions

  • Rob

    You recommend reservatrol for heart health and blood flow to the brain, yet at the same time, you discourage the consumption of peanuts which contain reservatrol and other healthy compounds. Please explain this contradiction.

    • David Perlmutter

      Rob: The problem with peanuts is that they are low in healthful omega-3 fats, and high in the un-healthy omega-6 kind.

  • Great information! Thanks for all of your efforts Dr. Perlmutter…

    • David Perlmutter

      Thanks Jason. All the best!

      • Same to you! You are doing fascinating work. I would love the opportunity to interview you for MindBodyMax.com and have your share more of your findings and ideas.

  • Sue

    I have just started reading Grain Brain. I am vegetarian. Any tips?

  • jane


  • Tim

    In addition to the supplements listed above do you recommend also taking a multi vitamin for everything else?
    Also does anyone know where you can get the required types of tests done in Canada?

    • David Perlmutter

      I do not advise multivitamins, but always consult your physicians on these matters.

      • Tim

        Just to clarify do you mean that you don’t recommend taking multi vitamins?

        Or you don’t advise on which brand/ type?

        Appreciate that I need to check with a doc as well. Thanks.

        • David Perlmutter

          “One-a-day” vitamins cannot make up for unhealthy eating habits. They can be an incredibly useful adjunct to an already healthy diet, but never ever a substitute.

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  • Events unfolding

    In addition to your recommended supplements, which I began taking daily after reading your book September, do you advise a daily quality multiple? If so, could you provide some recommendations? Currently taking Garden of Life raw for Women, but it is four capsules a day.

    • David Perlmutter

      You’re right to notice that a multivitamin is NOT listed. My message is straightforward: “one-a-day” vitamins cannot make up for unhealthy eating habits. They can be an incredibly useful adjunct to an already healthy diet, but never ever a substitute.

  • Karen

    Dr. Perlmutter, as a pediatric nurse practitioner I do my best to help parents deal with problems like ADHD, tics, type II diabetes and so forth. So I read your book with great interest and hope. I see that you’re now selling supplements for *$225/month(!)* The cost is outrageous and disappointing. Whatever promise you bring to people is called into question when it becomes apparent that you are motivated by greed. I thought you were the real deal, now, not so much.

  • Monica

    swansonvitamins.com sell Ultimate Probiotic Formula which covers more than 10 strains and consists of 60 billion organisms per capsule. I have checked them with Consumerlab.com which tests supplements and this brand passes the tests. Also less expensive than some.

  • Ashley

    Hi Dr. Perlmutter,

    Is Resveratrol safe to take while breastfeeding? Are all of the supplements you recommend considered safe for a nursing mother? Also should they be added in addition to my pre/postnatal supplement? Or is only a selection of what is listed above needed? Many thanks for your time and response in advance!

    • David Perlmutter

      Thanks Ashley, for the great question. There is no problem taking these supplements during pregnancy or breastfeeding. I can’t comment on your normal vitamins/supplements though.

  • RBinNJ

    You may have answered this question previously. In your book The Better Brain you devoted several pages to Co-Q10 and recommended supplements of 30 to 200 mg. In your latest book only a few paragraphs,mentioned Co-Q10 and it was not included in your list of important supplements. Is Co-Q10 no longer recommended as a supplement?

  • Maryann

    Hi Doctor Perlmutter,

    I read that MCT oil is not stored as fat; is that accurate please? If so, would MCT oil be as efficacious as coconut oil? Thanks!

  • Maryann

    Hi Dr. Perlmutter, why do you recommend one teaspoon of coconut oil per day in the book and at least two here? What is the amount to take for prevention and should Apo E people take more? Thanks!

    • David Perlmutter

      I generally say 1-2 tsp daily but a solid 2 is great, or more if there are ongoing neurological issues.

      • Maryann

        Thank you Doctor Perlmutter. Do you consider ApoE4 to be one of the neurological issues which would call for higher doses of coconut oil; if so how much? In an article by Dr. Stephanie Seneff of MIT, she cites E-4 as crucial for both the maintenance of sulfatide (important for meyelin sheath which deteriorates in Alzheimers) and cholesterol transport in the brain. Blessings to you and thank you very much, Maryann

  • anita

    i have been on your supplement regimen for about 2 1/2 months. all seems well, but i have noticed my gerd is a bit worse (not horrible). which supplement might be the culprit?

  • Gay H.

    Dr. Perlmutter,

    I always thought probiotics supplements had to be kept refrigerated but the only ones I can find that have 10 billion + cultures are not. Are the refrigerated ones any more effective than the ones on the regular shelf?
    Thank you,
    Gay H.

  • John

    Dr. Perlmutter, I was wondering if you could comment on the recent Hutchinson Cancer Research study and the correlation of EPA, DPA & DHA (derived from fish oil and fish oil supplements vs algae) and its link to a 71% higher risk of prostate cancer. I was wondering if you believe that the DHA derived from algae alone doesn’t contain the same risk?

  • Jessica

    I read your information on Benfotiamine. Do you still feel as strongly about its benefits as you did when you originally wrote about it (I believe the article I saw was from 2003)? And, if so, why is it not included in your list of super supplements?

  • Ryan

    Thanks for all the help guys, I have another question, I started supplementing with ALA and I developed the side effect of shortness of breath and slight tightness across the chest. The dose was 600mg a day as recommended above. There was no pain, but it was an uncomfortable feeling. I ceased use of it straight away and the side effect has subsided. Is this a normal thing to experience, is the dose too high or am I just reacting to the ALA unusually? Help would be greatly appreciated. Thanks!

  • Janice

    I have read that some wine barrels are sealed with wheat paste. I had to stop drinking red wine years ago because I always had bad reactions. I now know I have celiac disease and gluten sensitivity, so I am wondering if that is the reason. It didn’t seem to be related to sulfites.

  • Pam

    Is edamame okay to eat?

  • Straightthinker

    Although i have been a fan of a low carb diet for years, I am new to this. In fact, still not finished with the book. However, here is something delicious for all of you. For dessert I have a cup of hot almond milk with a teaspoon of coconut oil and a little sweetner. Really good.

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  • Kristi

    Does anyone know if Dr. Perlmutter’s new line of supplements is free of all the major allergens (I assume so but didn’t see it specified on the labels). No gluten, obviously, but what about dairy, corn, soy? Thanks.

  • Jody Williams

    My name is jody I have a problem with my balance not verto I have been tested I’m fine walking it’s just standing any suggestions?

  • fructmal

    Thanks Dr Perlmutter – I had your book sent to me in Australia and within two weeks my husband had lost 10lk and dropped his BP amazingly and consistently. However, as a severe fructose mal-absorber I struggle to find veggies /food to eat and as my Mother has just died of Alzheimer’s I need to follow your advice. How much buckwheat is a little per day – I need this to avoid bowel impaction, and is carob OK? I was having a little but I think this is a legume. Thanks again for all your work!

  • hugh casper

    dear dr could you reccomend a dr in the pgh pa area who would be an advocate of your program

  • Mimi Purnell

    I’ve read that Alpha Lipoic Acid and another, which I’ve now forgotten, are contraindicated for people treated for low thyroid. Any other info?

  • Mimi Purnell

    There is a newish Co. in Austin called BioTrust. One product indicates that it keeps blood sugar low and turns carbs to muscle, rather than fat. IC-5, Advanced Insulin Support and Carbohydrate Management. They have Cinnamon, Berberis aristata root bark extract, Pterocarpus marsupium, Fenugreek extract, r Alpha-Lipoic Acid (65mg.), I take 2 in the am and pm. Does this combination sound reasonable to you?

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  • Gabrielle

    Hi Dr.

    My brother has ALS. Is there anything he can do diet wise to improve the nerve cells in the brain and spinal cord now?

  • JenLee

    After reading your book, “Grain Brain,” I have begun a gluten free journey and lost 15 pounds without trying in 6 weeks! Now comes something that is confusing to me: I have been taking Rainbow Light Active Adult 50+, a food-based multivitamin for several years. While scrutinizing the Supplement Facts I find it contains ProbioActive (Bacillus coagulans) 25,000,000 CFU. I have tried comparing coagulens to acidophilous and find it difficult to understand what the difference may be. Two things: 1. Please comment on the comparison; and 2. Would this suffice for my daily probiotics intake and if not, can I take this 25 million plus a probiotic with 10 billion CFUs? Thank you!

  • JahbJoan

    I am so confused by all of the recent dietary advice. The idea of abandoning all grains and beans and anything that has to be processed before it can be eaten certainly makes intuitive sense since, if it must be processed then nature never intended us to eat it. And yet it can’t be denied that many people not only exist but thrive on a low fat, high carb, vegan diet. I saw the movie Forks Over Knives a few years ago that recommended just such a vegan diet. The doctors in that film (Esselstyn from the Cleveland Clinic, Campbell from Cornell, Barnard, and MacDougal) are reversing heart disease and type 2 diabetes by that diet. As a result, I thought that that must be the way to go. I bought their books and ate that way for 3 & 1/2 years and it almost killed me. I developed alopecia, hyperparathyroidism, and osteoporosis. I switched to the Paleo Diet not quite 4 months ago and am feeling much better. I’m getting blood work done tomorrow that I hope will show those other problems improving. The alopecia I stopped and reversed with 1000 mcg of biotin daily. But the point is, these are respected doctors; they’re not liars nor are the many patients that they’ve cured. But they’re following a diet that’s the exact opposite of Dr. Perlmutter’s diet and the Paleo Diet both of which also claim to reverse type 2 diabetes and, if not reversing heart disease, at least not to be bad for the heart. How is it possible that some people can thrive on the F. O. K. vegan diet while others, like me, can’t. I don’t get it, I don’t get it, I don’t get it. I wrote to the Forks Over Knives website asking about it but got no reply.

    • m

      I too hav seen forks over knives. And after watching it, I ws in awe. The reversal of dicease in those patients was amazing. I was 100% convinced tht animal-free was the way to go. And thn I came across gain brain. And I had to question my nutrition beliefs once again. I am so confused, so lost. O creator of this universe, guide me to the right path, ameen.

      • Gravity

        “the blood type diet” book may help. I read it years ago and my “I have red meat sitting in my gut for days” and my “I HAVE TO HAVE red meat, with no problem digesting it” husband were BOTH explained…..as I am a type A (no animal proteins recommended except for the occasional egg) and my husband is type O (plenty of meat, no grain – Paleo type).

    • maria

      I believe that different people have different nutritional needs. I have heard, for example, of some people reversing disease through a macrobiotic diet. I tried that diet and it didn’t seem to work for me. Paleo (of a variation of it) works better for me. I feel better and my health has improved. You have to find what works for you.

  • Melissa Moffitt-King

    Hi, I am wondering about edamame? Is this an okay food when following the Grain Brain way of eating?

  • LadyA

    Dr. Perlmutter, do you have any information or an opinion on tocotrienol for brain health? Advertised as an antioxidant rich in fat for the brain.

  • Joop Ketellapper

    Dear Dr Perlmutter,
    We have read your amazing book in dutch language.
    For several years we follow an eating behavior with very limited intake of carbohydrates. Also we use no milk and dairy products, with one exception. Each morning we eat the Budwig Protocol: low fat cottage cheese mixed with a lot of flaxseed oil. After the binding of the oil with the protein, the product has lost his dairy properties. There, we feel very good on. What is your opinion on the Budwig Protocol?
    With thanks and kind Regards,
    Joop & Tilly Ketellapper from the Netherlands

  • Jennifer Labelle

    Hello Dr. Perlmutter,
    Can you please post your recommended multivitamin supplementation dosages for children. I have a four year old and 20 month year old and want to make sure they are getting the correct nutrients and the correct amounts of those nutrients. If you also have time to post your recommendations for adult men and women, that would be great too : )

  • MiaGia

    Dr. Perlmutter, what are your thoughts on collagen with super C?

  • Stu

    I have gout and have to avoid high purine foods (meat, seafood, etc.). Will adopting the Grain Brain diet aggravate my gout?

  • Alisa

    I was wondering if you could suggest which probiotic from Xymogen you would recommend. Thanks!

  • Samm

    I was so impressed watching Dr. Perlmutter on PBS tv. I got so excited and went directly to the website thinking I would be able to get the supplements. To my horror I find that even just one of the supplements is more than my food bill for a month. I’m on SS only and us older folks that need these supplements the most cannot afford them. I’m so sorry about that. So to all of you that can afford them I wish you well and I’m sure they will help you.

  • becky williams

    The Tumeric capsules is causing me stomach cramps, and nausea, is the liquid form as harsh?

    • Danny

      I’m not sure, but I believe turmeric can aggravate ulcers. I also, wonder if that means that people w/ leaky gut should use caution w/ turmeric.

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  • Maryann

    Hi Dr. Perlmutter, Longevinex resveratrol says not to take within 2-4 hours of any medications. Do you think that this is particular to their brand and ingredients? Or do you give your patients this advice about all resveratrol supplements?

    Thank you for your life-changing work, we tell everyone we can to get your book! Maryann

  • Amanda

    Do you have diet information for vegans?

  • jamie

    Are there any concerns over the heavy metal chelating effects of Alpha Lipoic Acid?

  • Mac

    I’ve been adhering to a regimen of the super 7 supplements for the past several months and was looking for advice concerning turmeric. According to AJCN, turmeric can increase urinary oxalate, which is a great concern to someone that has a decades long history of episodes of calcium oxalate kidney stones. Any advice on mitigating the oxalate issue, other than the typical “drink plenty of water”. I’m in the middle of bout of urolithiasis. I’m not blaming my increased turmeric intake as the sole reason, but I definitely would like to decrease my future stone forming potential.

  • Cindy

    What is the ideal ratio of LDL to HDL and range for total cholesterol in your opinion. I’m off my statin and on a grain brain diet. My LDL is up but so is my HDL, but my total is at 299 which has me worried.

  • Judy

    Confused about DHA supplements. I see Dr. Perlmutter recommends 1,000 mg/day. I currently take Krill oil. Supplement lists: Wild &Whole Krill Oil 500 mg; Omega 3 fatty acids 150 mg; EPA 75 mg; DHA 50 mg. Does this mean I’m only getting 50mg of DHA or do the others factor into the total?

  • Anne

    You recommend 5000 IU Vit D initially. Couldn’t that result in increased chance of kidney stones?

  • Mikhalych

    Dear Mr. Perlmutter,
    IN my country it is not possible to obtain virgin/natural/whatever coconut oil/ Evidently they could be to some extent substituted by raw coconut meat.
    How much meat does a person need to eat daily, then? Is the situation as sad as with resveratrol/grape wine?


  • Guest

    Dear Mr. Perlmutter,
    In my country it is not possible to buy “natural”/”virgin”/whatever coconut oil. The most evident solution is to use coconut meat. If so, how much of this meat must a person eat daily?
    Or situation is as sad as with resveratrol/red wine?


  • Louise

    What kind of coffee should one drink black only?

    • David Perlmutter

      Certainly okay to mix in a bit of cream, or you hear of many folks using coconut oil or milk in their coffee.

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  • fer08fer

    what supplements should i get for my 10 year old on 3 anti epileptic drugs

  • michael

    Are organic quinoa & brown rice, grains to stay away from as well as the better known grains e.g.,whole wheat, rye ?? Thank you

  • John Galt

    How about supplementing with Vitamin C also?
    Why no mention of it?
    Thank you.

  • Great list of antioxidants. I’ve been taking a supplement with Resveratrol in it since I found that it’s a natural remedy for cancer or should I say it helps in cancer prevention. Although I’ve been taking it for years, this is the first time I’ve known of its benefits for the brain. Thank you!

  • Deena

    I noticed that ~2 weeks after I started taking Turmeric and Resveratrol my fingers and toes began to peel. I hope it has nothing to do with the supplements, but that was the only new thing in my diet. I have been grain free 7 months and am feeling great except for this new skin condition. Any ideas?

  • Gary

    Mr. Perlmutter, I still have not gotten your recommended Brands of supplements. can you please direct us to this site or list them in an email. Thank You.

  • Jim

    Why does the ‘Eat To Live’ diet by Dr. Fuhrman stress a high consumption of phytonutrients and the ‘Grain Brain’ diet have so few phytonutrients?

  • Carlee

    Are these supplements safe to take while breastfeeding?

    • David Perlmutter

      You should, of course, consult your physician. However DHA is one of the best supplements for pregnant moms-to-be.

  • Good day, good Dr. Perlmutter, In the past, I’ve been able to fast for periods of 5 days (no food or water), 21 days (water and coffee), 65 days (liquids only including milk, fruit juice, broths). Each was done for both spiritual and weight-loss purposes. In each case I lost a lot of weight (10 lbs., 30 lbs and 40lbs respectively), but gained it back over an extended period. I’m thinking of fasting for 5-10 days to start a grain-brain diet. I’m 76 and an avid cyclist.

    • David Perlmutter

      Certainly, consult with your physician before engaging in an extended fast of this nature.

  • Emme

    Hello! I live in Argentina and I am not sure if all of these things are available here. I am worried that I wont be able to get a hold on the 7 supplements.

    • David Perlmutter

      Unfortunately, we aren’t shipping my supplement line internationally yet. However, we are working to make them available soon.

  • DaB

    A few things bear mentioning re the list:

    ALA – its a combination of usable and unusable fractions (based on which way the molecule is twisted) – R-ALA is the usable part and available separately.

    Turmeric – this is difficult to absorb, so you get higher blood levels by using a micronized, Meriva or other form of circumin which is designed for better absorption. Its also oil soluble, so is better absorbed when taken with an oil (coconut or olive).

    DHA/EPA – also is much better absorbed when other food oils are in the stomach

    I’d also add #8: bioflavinoids, these and circumin are good for the brain in many ways including elimination of some unwanted metals.

  • Christine

    Dear Dr Perlmutter, I have lived your book and recommended it to so many. Also my husband and I are following your diet and are very happy with it. I do have concerns about Resveratrol though. Have you read Dr Raymond Peats article on the ” The great Resveratrol scam”. He puts a good case forward for this supplement. I will keep up the one glass of red though. What do you think?? Christine.

  • Christine

    Sorry the title is “Don’t be conned by the great Resveratrol scam” by Dr Raymond Peat Thanks Christine

  • Leslie Norins

    Great book! On page 222 you advise consulting your website for list of drugs which raise homocysteine. Have poked all around your site and can’t find this list. What have I missed? PS: Suggest your Web team add a “keyword search” feature to your HomePage.

  • Christine

    Is Coconut nectar a good alternative sweetener, if you have to have one? It says it’s similar to maple syrup only low GI. I only saw it yesterday for the first time. ??

  • maralina

    I have been reading that supplementation with “Vitamin” D3 is not a good choice; that it acts like a hormone and that when D is low in the body, it’s likely that taking magnesium will aid in synchronizing the body’s vitamin D from a mere 10 minutes of sun exposure every day.

  • Helen

    Can you suggest any cheaper supplements?

  • Barbara Hickman

    Adding coconut oil to a very longstanding good diet ( gluten free) turned corner for me. About a month ago I added modest amounts of Red Palm oil to it as well (1-3 teaspoons daily on top of 4-6 tablespoons virgin organic coconut oil). I am loving the results! Read Dr. Bruce Fife’s The Palm Oil Miracle & his The Coconut Oil Miracle. They work!

  • Jessica

    I read your information on Benfotiamine. Do you still feel as strongly about its benefits as you did when you originally wrote about it (I believe the article I saw was from 2003)? And, if so, why is it not included in your list of super supplements?

  • Deborah Herbst

    I just received my senior empowerment supplements and I wanted to know if I should take them all at night or all in the morning or break them in to certain groups?

  • gaylep

    Question about EPA vs. DHA. I’m not clear on the advantages of one over the other for inflammation / ADD…even after reading the book. Could you explain or write an article about the differences and why you recommend DHA over EPA? I’ve noticed several similar questions in your comments under other articles. I’ve also read about a study where patients were taking omega-3 for 6 months and showed vision improvement. Are you familiar with this, and if so, what sort of omega-3 were they taking (EPA vs. DHA again). I can’t find the article 🙁

  • Krissy ST

    My father has Type 2 Diabetes (but doesn’t have to inject insulin). It is safe for him to start taking ALA supplements? I’ve started him on turmeric, coconut oil, probiotics and fish oil and he’s feeling fine.

    • David Perlmutter

      ALA is a very safe supplement, and part of the seven I recommend as part of a Grain Brain supplement regimen. However, if you are concerned about adding it to your father’s daily intake, I would advise consulting his physician.

  • S

    What about MATCHA – Matcha Ninja do a great tasting matcha on Etsy. Blends with cold water too. https://www.etsy.com/ca/your/listings?ref=si_your_shop

  • Dennis Sagendorf

    I have been taking multiple vitamins and fish oil for years. I started taking your recommended vitamins listed in Grain Brain. Do you suggest I continue with the multiple vitamins plus your recommended vitamins?

    • David Perlmutter

      Depends on the full program you are taking. This is the full regimen I advise.

  • Suzanne

    Dr Perlmutter, you’re a very reassuring voice in the midst of medicine today. Can you tell us what you think of BioPQQ and CoQ10 as a supplement as a preventative and also for someone with established dementia (in the case with lewy bodies).

  • Jill

    Do you have a page with supplement recommendations for young children?

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  • Drayton Bailey

    Hi Dr. Perlmutter,

    Thank you so much for your book. It changing mine and my wife’s life. I cannot quite express just how much. Nevertheless I feel comfortable with your supplement recommendations however, could you please provide a example of a daily supplement (e.g. Morning take this, in the afternoon take this, in the evening take this)? I would just like some insight on what I should take when. Example might be during breakfast take multivitamin, fish oil(DHA), ALA, Reverstrol,etc. and so on.

    Thank you,

  • Christine

    Can you tell me what you think of red palm oil please.

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  • Megan

    What is Dr Perlmutter’s opinion on HGH supplement Serovital?

  • Jeanwf

    I have just ordered krill oil 500 mg but it says the DHA is 27.50 mg! Probably asking a really silly question but when you say take 1000 mg I am presuming this is just 2 tablets and not 36!!

    • David Perlmutter

      As I am not familiar with the product specifically, I would not want to comment.

  • Elias James

    Hello friends, I’m from Austria
    I want to tell the whole world about the good deeds DR.OBOH did for me, I was diagnosed of a cancer disease (liver cancer), I was told by my family doctor, that I have only 8 months to live on planet earth, I was so depressed, I was thinking about my family, I don’t want to leave them behind, THEN i heard that DR OBOH is curing HIV/AIDS in that case he can also cure your cancer disease, I never believe in spell, I collected his email from him, then I contacted him via email, he told me not to bother myself, that everything will be alright, I believed him, due to the way he said it. He asked me to purchase some items, which I did, he casted the spell and tell me that am free from the bondage, he also asked me to go for checkup, the CANCER disappeared from my body totally, I am forever in debt to him, I owe you a lot Doctor. If you have any deadly disease like HIV/AIDS, ALL TYPES OF CANCER, GONORRHEA, SYPHILIS, and ANEMIA any disease you can think off. Kindly email him now on drobohspelllworks@outlook.com or drobohspellworks@gmail.com

  • Dimitry

    Hi Dr Perlmutter,
    My 28 year old younger brother recently had an accident which caused him to fall 16 feet from the ground and he now faces traumatic brain injuries. I have been with him in hospital for the past 3 weeks he is doing much better than everyone expected. The paramedics predicted that he would die in the next hours. He is currently still in a induced coma fighting. He has developed multiple brain injuries. I just finally convinced doctors to include fish oil into his diet, after much research they have agreed. Now I’m trying to convince to give him a daily dose of resveratrol. He’s at the Cornell presbyterian hospital in New York. Can you please recommend some other treatments or give me advice? Please help doc .

  • kisha

    Can obest prediabetic children take curcumin supplements ages 8 and 9

    • David Perlmutter

      Absolutely. Just consult with a pediatrician.

  • Grandma Sharon

    Question on supplements. Wouldn’t a persons weight make a difference on the servicing size or IU’s that should be taken? Example- D3-5000IU’s.

    • David Perlmutter

      Focus on measuring your current levels and adjust a dosage from there.

  • Sandra Sam

    Hi, Thanks Dr. Perlmutter for the great information. I’m currently taking resveratrol supplements and I definitely like it.

  • Lisa Muzic

    Does grape seed extract have the same benefits as Resveratol?

    • David Perlmutter

      Overall, the research supportive of Resveratrol is far more robust and compelling.

  • Searcher

    Dr. Perlmutter,
    I have been diagnosed with “complex migraine” about 4 years ago. I was advised by my doctor to watch for” triggers’ such as all nuts, yellow cheese, chocolate, etc. These triggers still are causing symptoms in me, although I have been trying to follow your recommendations for about a year. Any suggestions? I have read both Grain Brain and the accompanying cook book! I have given a few away. They are great! Thanks Jon 🙂

  • Lisa Muzic

    Grape Seed Extract vs Resveratrol?

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  • Lisa Muzic

    Perhaps 3rd time is a charm: are grape seed extract supplements as effective as Resveratrol?

  • Katieaz

    Is there a best time to take vitamins and supplements such as the 7 recommended?

    • David Perlmutter

      I would check the labels on the supplements you’re taking. May be some information there.

  • Emma Jurgens

    • MY HIV DISEASE WAS CURED BY DR NICE, WITH HIS HERBAL HEALING SPELL/ (drniceharbelhealinghome@gmail.com).DR NICE is the only Dr who could ever get my HIV-AIDS cured with his healing spell, I have tried almost everything but I couldn’t find any solution on my disease, despite all these happening to me, I always spend a lot to buy a HIV drugs from hospital and taking some several medications but no relieve, until one day I was just browsing on the internet when I come across a great post of! Michelle! who truly said that she was been diagnose with HIV and was healed that very week through the help of these great powerful healing spell doctor, sometime I really wonder why people called him DR NICE I never knew it was all because of the great and perfect work that he has been doing that is causing all this. so I quickly contacted him, and he ask me some few questions and he said a thing I will never forget that anyone who contacted him is! always getting his or her healing in just 6 hours after doing all he ask you, so I was amazed all the time I heard that from him, so I did all things only to see that at the very day which he said I will be healed, all the strength that has left me before rush back and I becomes very strong and healthy, this disease almost kills my life all because of me, so I went to hospital to give the final test to the disease and the doctor said I am HIV negative, I am very amazed and happy about the healing Dr NICE gave to me from the ancient part of Africa, you can email him now for your own healing too at :drniceharbelhealinghome@gmail.com

  • Hey Really a Good Information to share !! These are really a pure natural one and I suggest every person to get the best supplements you can take so that it will get the best benefits to your body..

  • Paul

    Does ALA affect hypothyroidism? What is the best amount to have if you have hypothyroidism?

  • Larry Kellogg

    Dr. Perlmutter, can you advise regarding NMN? A researcher at Harvard studies this compound. If advisable, where does one get it?

  • This post tells us about the supplements which is used for improving brain power and other illness. Good information have been given about the properties of different supplements which can be useful for us as which supplement to use as according to the requirement of the body.

    • David Perlmutter

      So glad to know you find value in this information.

  • Suzie

    Do you recommend a certain company to buy good supplements from?

  • Sharon

    I was told that low doses of non pharmacological lithium, (which must be either lithium orotate or lithium aspartate) was really great for the brain and nervous system, protected against dementia, helped grow brain cells, and a host of other amazing things. Does anyone have information as to whether or not this is true? Is it safe? I was told it was totally safe. Dr. Perlmutter, do you have any information about this?

  • John Williams

    Turmeric is recommended to get the benefit of curcumin, would it not be better to take a concentrated curcumin supplement if that is the part we are after?

  • Jeff

    For the last 4 years I’ve been buying grass fed organic cows milk from a local dairy. Is this a bad food to be in my diet?

    • If it is whole milk, pasteurized–but not homogenized–by the low-temp, small-batch pastuerizing method, and especially if the cows are primarily Jerseys with their high butterfat content, the flavor is so much better than the other stuff that I’d drink it if it was poison.

      • Jeff

        it’s unprocessed straight from the cow. And yes, its delicious.

  • joe

    If you drink wine regularly (1-2 glass/day) , would you need resveratrol as a supplement?


  • Christy B

    Hi Dr Perlmutter, I am new to all this. What should your cholesterol levels be and what do you suggest for osteoporois?

  • Proper exercise and hydration, and taking care of your body in general, are especially beneficial to your brain.

    • David Perlmutter

      Both are incredibly important as well.

  • Andy Koz

    There is actually a supplement called Brainz Power, and it has 9 ingredients, including most of the ingredients above, targeted to help your brain and its everyday functions. I use it everyday and it works very well. If you want to check it out I linked it below.


  • Barbara Dale

    After being on the Grain Brain diet since the book was published. Thank you so very much for your stellar work. What are your general thoughts on the most effective treatment of osteoporous?

  • Ginger

    Desperate! My husband John is a diabetic with bone infection in the ball joint of his big toe. He has been on antibiotics for 10 + wks and been going in the hypobaric chamber for 10 + wks too. We desperately need your help. The next step is to cut off the big toe. Desperate wife Ginger HELP!!!

  • How about this “protein from a jelly fish shown to improve memory?”

  • mondvp

    Good morning Dr. Perlmutter,

    I need to know which of their supplements can be taken during pregnancy and at what dose .

    Thank you very much

  • Robert Cox

    I have doubts about Vitamin D over-dosing causing thyroid/calcium problems. Hyman/Davis/Perlmutter seem to be a self-referencing trio. I’m not going to start paying stupid money for supplements. A proper choice of FOOD is all one needs. Please don’t inform and advertise at the same time – it’s kind of like sucking and blowing, too many web-sites with fantastic claims. Cynicism is the new religion.

  • John Landau

    Caution: Anyone taking Alpha-lipoic Acid needs supplemental biotin. ALA depletes stores of biotin. My thick beautiful hair turned into straw and fell out. Sadly, it has never recovered. I suggest taking at least 2000 mcg. biotin.

  • Stacy

    Just finished the Grain Brain book. We want to start the diet but my wife is a vegetarian because of her Buddhist beliefs. Can we adapt the plan accordingly?

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  • K.C.

    Wonderful and insightful information! Thank you so much. Considering these foods/supplements are often taken with iron and zinc and that they are also important minerals for absorption process, would you happen to know to what extent, lets say in percentage iron and zinc are nullifying each other when taken at the same time?

  • Brooke

    Dr. Perlmutter, I’ve just had my 3rd child, is it okay to include prenatal vitamin along with your list of supplements? Also I’ve recently experienced my first kidney stone with continued kidney infection other than abx is there anything else I can take for prevention?

    • David Perlmutter

      That sounds like a discussion to have with your OB/GYN.

  • jean

    Which Supplements manufactures are reputable since its not regulated?

  • Pam Windham

    I have a problem maintaining weight. I am losing weight on the grain brain diet. Any suggestions for supplementing the diet to keep my weight up?

    • David Perlmutter

      Try increasing the amount of healthy fat in your diet Pam.

  • bchesirb

    Does Splenda (and other “sweetners” raise your blood sugar level or not? I am getting conflicting reports on this.

    • David Perlmutter

      If you’re looking for a sweetener, the best option is stevia.

  • Judie

    Hi all! Dr. Perlmutter, can you please tell me if I can eat extra firm organic gF tofu? And please also, what the problem is with soy milk? Just getting started gf and am vegetarian so I do use soymilk and tofu. (I do eat fish)

  • Amy Conchilla

    What is your recommendation is for the EPA/DHA ratio? I am taking 600 mg DHA (GNC supplement). I was told 3:1 ratio is preferred.

  • Katie

    Dr. Pearlmutter, I’m confused about the oil chart in your book,page 75-76. Why is walnut oil better than canola,it has 52% omega 6’s, which i thought were bad, and canola is only 1% lower in 3’s, but only 20% in omega 6’s. It seems to me, canola might be better. Please explain! I love grain brain book,the only thing that bothers me is I’m sleepy a lot. Any ideas?

  • Skull Bones

    I just got diagnosed with GOUT, and reading this actually made me feel like crawling and crying like a baby. The outbreak I have right now is genital and in my throat and mouth, I talked to the doctor who did the blood test on me and said over time that it would eventually get much better. She said that what I’m having is a massive outbreak and is unusual, but that it may be due to the fact that I stressed myself out over it so much. She also told me even though I have it in the genital area that It doesn’t mean that I needed “private to private” contact to acquire it. But this did make me feel a whole lot better about the whole situation. For anyone else to has GOUT after all this stress and pains am passing and the doctor saying all such of crap i was not convince by his Theory so i decided to go on the internet and saw this comments by Rose who testify about how she get cured by root and herbs by Dr ahineh, when i first bump into it i didn’t believe the comments at first so i decided to confront her on Facebook and really know what and how did it work because my doctor told me there is no cure for herpes, so i really ,,contacted DR AHINEH, he responded in A minute the only thing he ever ask for was just the items of which he will use to prepare for the herbs, after all this he send the herbs through courier Services, within a week i was cure just like that without no struggle or stress, if you are out there in need of cure contact him with his email address, DRAHINEH@YAHOO.COM OR CALL HIM ON +2348158665394

    he also cure HIV
    and diabetes

  • Susan Moore

    Appreciate to dr okoh. Dr Okoh God will always continue to bless you more abundantly, for the good works you did in my life, I will always keep on writing good and posting my testimonies about you on the Internet, I’m Susan Moore from San Juan, Puerto Rico. I was tested HIV positive, I saw a blog on how Dr Okoh cured people, i did not believe but i just decided to give him a try, I contacted him and also got my healing, i am so happy. If you have any problem or you are also infected with any disease, you can contact him on WEBSITE: http://drokohspelhome.wix.com/drokoh or +2348153089532 and EMAIL: drokohspelhome@gmail.com

  • R Shannon

    Don’t you need Vitamin K to help the Vitamin D assimilate in your body?

  • Lucia

    Did anyone find a supplement that would combine at least some of these into one, so I dont have to buy 7 separate bottles? Thank you!

  • naturally paleo

    If most people don’t get enough DHA, if any at all than how does the brain consist of more than 50% of the stuff?

  • vicki

    @Dr. David Perlmutter MD..Questions: What are your best suggestions for kidney and liver cleanses when medium kidney function is a factor from years of high bp and also use of D when high calcium presented in bloodstream of same stage 3 kidney patient?

    What do you suggest for anti fungal, reduction of Candida overgrowth besides the removal of all “white/processed foods”?

  • vicki

    Am using turmeric, vitamin C and coconut oil as anti parasitic, what if anything else would you suggest to rid body of any parasites or residual toxins after a roundworm infestation?

  • Colin

    If you have high cholesterol and borderline diabetes, can you still have coconut oil?

  • Joe Texan

    I have been using alpha-lopic acid since you recommended it for toe neuropathy and after a year my toe neuropathy is gone. But, Sherry Rogers, M.D. says that r-lopic acid works better. What is your opinion?

  • Joe P

    Dr. Perlmutter thank you for all this information you are giving people about Brain health. I believe what your saying is true. We are a sick society filled with fast food garbage. Its killing us. Its time for good people as yourself to blow the whistle on the damages of gluten and processed sugar. Enough is enough. Too many sick people in hospital rooms and morgues because of the bad food choices. Like God said. My people perish from lack of knowledge. Its time to listen…

  • Robert Miller

    I got great information through this blog post. WOuld you suggest me some diet plann to fit.
    Dr. Whitetaker Focal Point Review

  • Manik Sood

    1) Do DHA supplements improve memory only or they improve IQ also? 2) Can these supplements be taken by any age person or are recommended for certain age group people? 3) Is it safe to take 120mg DHA & 180mg EPA for a prolonged period? After how much time a break should be taken to discontinue and start the usage of omega-3 supplements again?

  • Joni Walker

    Dr. Perlmutter: I’ve been recently diagnosed with MS through MRIs/MRA’s. I have mild-livable symptoms My regimen is good ~ 5,000 iu Vit D, plant-based calcium & multi/mineral, Ubiquinol, probiotic, pharmaceutical grade Omega 3. I’d like to incorporate brain-booster supplements, anything you can recommend with aminos like vinpocetine, tyrosine, etc. (or others) that will support cognitive performance and memory? Thanks.

  • Linda

    Dr. Perlmutter, what are your thoughts on alpha lipoic acid and Andy Cuttler’s protocol for using it to chelate? Curious why one couldn’t just take a higher dose instead of doing around the clock for 3 days at a time.

  • Health Produkte

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  • Johnson James

    Thank God Almighty that led me to Dr OSARO who with his
    humanitarian heart helped my mom that had
    diabetes with his Hemp Oil. I am so grateful that my 54 years old mom is
    back alive and healthy and can do all the things she like without any hindrance
    in her life. Dr OSARO, your medication is the only cure for cancer, tumor and
    from the bottom of my heart, I sincerely say you are the best and I will always
    give thanks to God for you to have long life so you can help many more people
    on earth with your medical service to humanity
    .with you I now believe that the hemp Oil is real and True, for all
    those who have problem relating to diabetes and other diseases should contact Dr OSARO, You
    can email him on: drosarospelltemple86@gmail or call him on +2349082513668

  • alexcyril

    hello friends, my name is maria burgos i want to testify on how i was cured of my diabetes by herbal doctor chima okereke, i have suffered from diabetes for years and have been to different hospitals for cure but all effort was in vain. so while i was on net i saw so many testimony’s about doctor chima okereke on how he cured so many diseases and virus so i decide to contact the said doctor and explain to him about my diabetes so he promise to cure me after all arrangements have been made he prepared the herbs and sent to me in my country and i took it behold i was totally cured,now i’m happy to testify that i’m cured of my diabetes, so if you are suffering from diabetes and you want a total cure contact Doctor chima okereke on drchimaokereke@gmail.com or call him on +2347067847693

  • Edward Miller

    In this post, you may modulate the effects of stress, anxiety, and depression for your health.
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  • Elói Ângelo

    Hi all,

    Is there any home test to do to omega-3 suplement (liquid capsules) in order to garantee the quality of the product?

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  • Robbie Angelic

    I can’t believe my genital herpes is really cured, oh is by this time last year I start feeling bad about my life, I feel pain everyday of my life am very happy now that am really cured I couldn’t have do this on my own I wish is not God that help me with my helper I was searching the Internet about this sickness last 5 month when I found about great doctor abegbe, the man that keep his words I write the man email about my problem immediately I get a reply from him asking me to fill a form which I immediately did and send back to him after some mins he reply me that he have work on my cure that I need to provide some materials, which can enable him to work on my cure which I did on the next day of it, after some hours he inform me that he have getting the things needed for the cure and he is about to go on with the curing spell he called me again after 50mins that he is done with the cure that I should check my body and also go for test I cant believe I was negative a big thanks to him am very happy now with my family you can also get your self cured too from this sickness by contact him through Email: DR.AJAHHOMEOFSOLUTION@outlook.com, He also have a herbal cure for 7 other DISEASES;
    8 HPV
    Contact him today and you will have a testimony…Good luck!..

  • Alvis Brown

    Great five steps to cure diabetes. In June of 2015, it was discovered that I had type 2 diabetes. By the end of the month, I was given a prescription for Metformin. I stated the ADA diet and followed it completely for several weeks but was unable to get my blood sugar below 140. With no results to how for my hard work, I panicked and called my Doctor. His ? Deal with it. I began to feel that something wasn’t right and do my own research. Then I found Rachel’s blog ( WHO SAID SHE WAS CURED FROM DIABETES WITH THE HELP OF A HERBAL DOCTOR,CALLED DR IRISO ” ) And i contacted the Dr iriso on his via email;(dririsosolutiontemple@gmail.com). and he reply me back i explain my problem to him and he said he is going to help me that it will take him 24 hours to consult his gods,The nest day he called me and as me to go for cheek up,and i went to my doctor, and I lost 30 pounds in the first week and lost more than 6 inches off my waist and I’m able to work out twice a day while still having lots of energy. The truth is we can get off the drugs and help myself by trying natural methods so i will advise you to contact hem on this via email;( dririsosolutiontemple@gmail.com ) or call him on his mobile number +2348074876448 god bless you

  • Alvis Brown

    Great five steps to cure diabetes. In June of 2015, it was discovered that I had type 2 diabetes. By the end of the month, I was given a prescription for Metformin. I stated the ADA diet and followed it completely for several weeks but was unable to get my blood sugar below 140. With no results to how for my hard work, I panicked and called my Doctor. His ? Deal with it. I began to feel that something wasn’t right and do my own research. Then I found Rachel’s blog ( WHO SAID SHE WAS CURED FROM DIABETES WITH THE HELP OF A HERBAL DOCTOR,CALLED DR IRISO ” ) And i contacted the Dr iriso on his via email;(dririsosolutiontemple@gmail.com). and he reply me back i explain my problem to him and he said he is going to help me that it will take him 24 hours to consult his gods,The nest day he called me and as me to go for cheek up,and i went to my doctor, and I lost 30 pounds in the first week and lost more than 6 inches off my waist and I’m able to work out twice a day while still having lots of energy. The truth is we can get off the drugs and help myself by trying natural methods so i will advise you to contact hem on this via email;( dririsosolutiontemple@gmail.com ) or call him on his mobile number +2348074876448 god bless you.,,,,

  • Connie Birthright

    I have not seen this problem addressed: I took a week trip to CA and inadvertently left my 5 of my supplements at home. I started back on them when I returned but had a bad case of diarrhea. I stopped for several days but each time I start again I have diarrhea. Which one could be causing the problem – Omega 3,Turmeric, Resveratrol, Probiotic 15-35, or Alpha Lipoic Acid?

  • Connie Birthright

    Which supplement/s can cause diarrhea?

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  • Tanya Wilson

    My name is ivar khan am from India and i lived in the united state of America i want to use this process to thank the general public and most especially to the Herbal doctor who cured my impotence DR.OROROGUN an Africa herbal doctor.I have been suffering from this erectile dysfunction from the past 6 years after giving birth to my first daughter,as a result of me not be able to prove my self as man any longer due to my condition was almost destroying and terminating my marriage to the extend of me trying to commit suicide.I have gone to many hospital and i did all kind of test and the condition still persist and also complained to s a pastors they prayed and the condition was even getting worst which always make me cry when ever am sleeping beside my wife at night.On a very good day i was reading through the internet on how impotency can be cured and i saw a documented testimony of Gabriel Wilson who shared a testimony on how he was cured by Dr.Ororogun and he gave the email of the herbal doctor which was OROROGUNHERBALHOME@GMAIL.COM which i also contacted all glory to God and to the herbal doctor i resume my duty as a man again and my wife just put to bed a set of twin baby bouncing boys after many years and i no there are men out there whether old or young suffering from impotency do not be shy contact him via the email above and you can also call his tell number +2349033470441 to get you cure it works like magic indeed the man is a great herbal doctor.

  • Ivar Khan

    My name is ivar khan am from India and i lived in the united state of America i want to use this process to thank the general public and most especially to the Herbal doctor who cured my impotence DR.OROROGUN an Africa herbal doctor.I have been suffering from this erectile dysfunction from the past 6 years after giving birth to my first daughter,as a result of me not be able to prove my self as man any longer due to my condition was almost destroying and terminating my marriage to the extend of me trying to commit suicide.I have gone to many hospital and i did all kind of test and the condition still persist and also complained to s a pastors they prayed and the condition was even getting worst which always make me cry when ever am sleeping beside my wife at night.On a very good day i was reading through the internet on how impotency can be cured and i saw a documented testimony of Gabriel Wilson who shared a testimony on how he was cured by Dr.Ororogun and he gave the email of the herbal doctor which was OROROGUNHERBALHOME@GMAIL.COM which i also contacted all glory to God and to the herbal doctor i resume my duty as a man again and my wife just put to bed a set of twin baby bouncing boys after many years and i no there are men out there whether old or young suffering from impotency do not be shy contact him via the email above and you can also call his tell number +2349033470441 to get you cure it works like magic indeed the man is a great herbal doctor.

  • wanda Dancy

    hello friends I am Wanda dancy from U S A. God is be really good to me in my life,, before people said there is no cure on HIV AIDS, but today many people have now believe that there is a cure for HIV AIDS it can be cured through Africans root and herbs, our great doctors have finally found the cure of HIV AIDS, many have get cured with the help of a great herbal doctor known as Dr uwa he’s the one of the great spell herbal doctor in Africa and he has the cure on this disease H.P.V/TYPE 1 TYPE 2 TYPE 3 AND TYPE 4. TYPE 5, human papilomavirus, genital warts, herpes, syphilis, cancer, hepatitis a b and c. high blood pressures, body disease, diabetics, epilepsy, HIV aids, pregnancy,ALS and many difference kinds of diseases, last month he share is Herbal medicine in some medical hospital and now he is well recognize as one of the best spell caster in Africa, you don’t have to be sad any more or share your tears any more on this disease when the cure have already be found. in 2015 the total number of people living with HIV was 5.8 million but today the total number is now 2.0 million, if you want to get in touch with him contact him on this e-mail below: druwaherbalcenter@gmail.com cell phone contact +2349052627511 his whatsapp contact is +2348063930531. so now contact him and get rid of your disease. immediately because this disease are not melt for us, with GOD all things are possible, so GOD has use this great dr uwa of dr uwa herbal center to let people no that this disease are not actually melt for us. and also here is my email address you can get in contact with me if you wish to no more about this great wonderful herbal doctor that has so much made me believe in him ok, so here is my email address wandadancy1@gmail.com thanks everybody and most especially you dr uwa of druwaherbalcenter@gmail.com .

  • Eddie Garza

    Most of Resveratrol on the market is made from Japanese Knotweed. Is this as beneficial as the resveratrol made from grapes? Thanks

  • Amanda Jane

    I’m giving a testimony about Dr Osemudiamen the great Herbalist man, he
    has the cure to all manner of diseases, he cured my herpes simplex
    virus, though I went through different website. I saw different
    testimonies about different spell casters and herbalist, I was like:
    ‘Many people’s have the herpes simplex virus cure why are people still
    suffering from it? I thought of it. Then I contacted Dr Osemudiamen via
    email: drosemudiamenspellhome@gmail.com. I didn’t believe him that much,
    I just wanted to give him a try, he replied my mail and Needed some
    Information about me, then I sent them to him, he prepared it (CURE) and
    sent it to me Fed-ex delivery, he gave my details to the FedEx Office,
    they told me that 2-3 days I will receive the parcel and i took the
    medicine as prescribed by him and I went for check-up 2 weeks after
    finishing the medicine, I was tested herpes simplex virus negative. if
    you are herpes simplex virus patient do me a favor by you contacting him
    and I assure anyone who is suffering it, your problem will never remain
    the same again you will be cured. Also Dr Osemudiamen help my sisters
    husband to cure his HIV/AIDS he was suffering from for the past 3 years.
    After he cured my herpes simplex virus, then my sister heard about it,
    she went home to tell her husband about Dr Osemudiamen then her husband
    emailed him and explained his problem to him. He also prepare herbal
    medicine and he use fed-ex delivery to sent him the herbal medicine and
    he instruct him on how he will be using it for 14 days. That on the 15
    day of it, he should go and check his self in the hospital and he did as
    he was instructed by Dr Osemudiamen. To GOD be the glory he was cured
    of his HIV/AIDS which he was suffering from for the past 3 years thanks
    to these great man we will ever remain grateful to you Sir indeed might
    work you did in our families. When you contact him, make sure you tell
    him that I refer you.. contact him via: drosemudiamenspellhome@gmail.com

  • Williams Kentasha

    Join me celebrate for these great and perfect day which my lord god has done for using these great and powerful healing doctor called doctor Alika to heal my sickness (HIV/AIDS) which has been chocking me up for over 3year now without solutions, i have seek for solutions online, and through hospital, they keep on giving me orientations about drugs that can extand my years.now since doctor alika has helped me to erased my disease out of my life, i we owe you greatly for healing me truly and to again, contact doctor ALIKA for your cure today at: doctoralikaherbalhome@gmail.com

    EMAIL.. .doctoralikaherbalhome@gmail.com

  • Joyce Rodwell

    from USA am here to give my testimony about Dr Orima
    who helped me cure my HERPES (HSV), i want to inform the
    public how i was cured from (HERPES SIMPLEX VIRUS) by Dr
    orima, i visited different hospital but they gave me list of
    drugs like Famvir, Zovirax, and Valtrex which is very expensive
    to treat the symptoms and never cured me. Three months ago
    a friend suggested that I try herbal medicine; from a very
    powerful herbal doctor called Dr Orima. I looked up his blog on
    the internet site and indeed he have had immense success
    with his product. There were lot of persons posting their
    testimony about how he cured them. when i contacted him he
    gave me hope and send a Herbal medicine to me that i took
    and it seriously worked for me, my HERPES result just came
    out negative. My doctor was shocked how i got cured. I am
    so happy as i am sharing this testimony. My advice to you all
    who thinks that their is no cure for herpes that is Not true just
    contact him and get cure from Dr orima spell Center. He
    can cure of all kinds of STD you may have. Remember your
    health is precious email him with his email as;
    (drorimaspelltemple@gmail.com ) or call him
    +2348138140874 he can also help the following problems

  • Reid Saunders

    looking for information on Phosphatidylserine as a brain support. Havent seen anything in quite a while. Is there any recent clinical data?

  • zmrzka333

    Good day. I am from Slovakia. I bought your book Grain Brain. Do not know what went wrong, but our translation is given in 7 super supplements that turmeric daily dose is 500 mg 2 times a day. Coconut oil 1 tsp. Alpha-lipoic acid 300mg daily. On your web site is listed Turmeric 350 mg 2 times a day and 1-2 tablespoons of coconut oil. Alpha-lipoic acid is 600 mg per day. Now what is true? The whole family, we are beginning to eat in design-tested according Grain Brain. We have 8 year old son and 5 year old daughter. Children can also use your 7 Super Supplements? Neurologist recommended the 8 year-old son under the EEG eating chlorella, probiotics and folic acid and the right gluten free diet and the exclusion of sugar. It was examined because of suspicion of ADD. EEG biofeedback son is training and practicing INPP method. According to therapists do not suffer from ADD or ADHD. It has only a few primitive reflexes present. Even though we adhere to a gluten-free diet and we learn to eat according to your book. Therefore, I would like to know if my son to use your 7 super supplements or supplements should be used in our neurologist. Or to some reasonable compounded? Thank you

  • ron

    I understand that all oil should be avoided as there is no nutritional value and mostly calories in all oil, including olive and coconut oils.

  • Mark

    Dr. Perlmutter,
    You mention that Alpha-Lipoic Acid is good for diabetic neuropathy, but I have not been diagnosed with either Diabetes or Peripheral Neuropathy. I do have burning and numbness primarily in my feet, but also some in my hands and face. Would Alpha-Lipoic Acid help this condition as well?

    I can say I’ve had 2 different EMG and Nerve Conduction studies that show my nerves are healthy. Desperately looking for something to take the pain away.

  • tyler brittany

    i want to thanks dr.Ade for the marvelous work he did in my life, i have been suffering herpes for three years now, and i have applied various medical drugs but they were all in vain,m i have been treated in different medical hospital but my condition remains the same till i finally concluded that there were no cure to my illness, i was searching through the internet when i saw a comment by monica on how she was cured by dr.Ade and she stated in her comment that ever since she had been cure that she had never had any outbreak so i dint believe her because i believe there was no cure to it.but i decided to contact the doc with the email she dropped, and he replied and ask me few questions about my body , he prepared the herbal cure and send it to me through FedEx and after i have taken it for one week and two days as i was instructed then i went for a test to my greatest surprise my result cam out negative, am so happy right now and if you are suffering of any kind of disease you can contact he on his email Adespelltemple@gmail.com or call +2347057375409 or +2348148487280
    he can as well help in the following:

  • Fabiana de Oliveira

    Can I put in this suplements the Safflower oil?

  • Fabiana de Oliveira

    How about Safflower oil?

  • Lisa

    I just started using a DHA (500mg) and EPA (70mg) and it contains Fish Oil concentrate (750mg) a total Omega 3 (649mg) This is Suzy Cohen DHA Script. Her line is targeted for people with problems with thyroid.

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  • Leoni

    In your Book you say you’re sharing some of your favorite brands for supplements on your webpage. I couldn’t find the link so far. Could you please help me out.
    Thanks for the great work and the detailed info on all of this. Couldn’t be better.
    On my way to optimal health,

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  • Scott

    Hi Dr. Perlmutter. What’s the best supplement for resveratrol (muscadine grapes, something else…)?

  • Gary Roger

    I was recently free from Chronic obstructive pulmonary disease(emphysema)if not from total cure herbal foundation,i suffered with copd emphysema disease for over 9yrs which i smoke for 29 years,it wasn’t easy in anyway living with this deadly disease,i cried for help everyday which i also spend almost all my money on, i was at the point i nearly gave up because i heard a lot of stories that there was no cure for it,i tried all the medications doctor around gave to me yet nothing happened tho it was able to be control at least,august 23rd 2017 i came across an article someone explaining how she was cured by TOTAL CURE HERBAL FOUNDATION in Joburg,so i contacted totalcureherbalfoundation @ gmail. com….and their website ….https :/ /totalcureherbalfou .wixsite.com /website to see if this was true,but right now i;m here giving the same similar testimony on how they gave me alternative way to cure this disease with their organic natural herbal products without any side effect,do email them now to see for yourself.

  • Colin Bevis

    I have been reading your posts regularly which is specially for hbuy hgh onlinee .I need to say that you are doing a fantastic work. Please keep it up the great work.

  • john peter
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