FBPixel An Evolutionary and Mechanistic Perspective on Dietary Carbohydrate Restriction in Cancer Prevention - David Perlmutter M.D.

Science

Study Title
An Evolutionary and Mechanistic Perspective on Dietary Carbohydrate Restriction in Cancer Prevention
Publication
Journal of Evolution and Health
Author(s)

Eugene J. Fine, Colin E. Champ, Richard D. Feinman, Samuel Márquez, Rainer J. Klement

Abstract

The confluence of basic cell biochemistry, epidemiological and anthropologic evidence points to high dietary carbohydrate and the associated disruption of the glucose-insulin axis as causes of the current increase in metabolic disorders, metabolic syndrome, hypertension and cardiovascular disease. This hyperinsulinemic state likely contributes, as well, to an increased mutagenic microenvironment, with increased risk for cancer. This critical review discusses these risks in their historical and evolutionary context. The evidence supports the benefits of lowering the glycemic load of the diet as a preventive measure against the development of cancer.

Date
September 20, 2016
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Related Topics

KetosisCarbohydratesKetogenic DietCancer

Dr. David Perlmutter is on the cutting edge of innovative medicine that looks at all lifestyle influences on health and illness.

Andrew Weil, MD