Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, is almost uniformly fatal and is only increasing in incidence. While no one has as yet been able to pinpoint what may cause this disease, a new report published in the journal, JAMA Neurology offers up some important clues.
The study evaluated blood samples from 156 individuals with confirmed ALS and compared them to blood samples from 128 similarly aged controls. Blood concentrations of 122 environmental pollutants were studied, including organochlorine pesticides (OCPs), polychlorinated biphenyls (PCBs), and brominated flame retardants (BFRs), using highly sophisticated techniques including gas chromatography–mass spectrometry. To be sure, these chemicals are directly toxic to the nervous system and are highly persistent in the environment, as well as in the human body Continue reading
Amyotrophic lateral sclerosis (ALS) is a progressive, and almost universally fatal neurological condition. Recently, I, like many of you, participated in the Ice Bucket Challenge to help raise not only awareness of ALS, but also to raise money for clinical research with the hope of finding a cure for this devastating condition.
While the actual cause of ALS remains elusive, new research is revealing that lifestyle factors, especially food choices, may play a significant role in determining risk for this condition.
In this month’s issue of JAMA Neurology, Harvard researchers published results based on an analysis of more than 1 million participants in terms of diet and risk for this disease. In this large group of adults, a total of 995 ALS cases were documented to have occurred during the course of the study.
Here’s my take on the ALS Ice Bucket Challenge.
To learn more about ALS, view one of my previous blog posts on the subject.
Amyotrophic lateral sclerosis (ALS) also known as Lou Gehrig’s disease, is a challenging progressive neurological disorder for which there is currently no meaningful treatment. As many as 30,000 Americans may suffer from ALS and the life expectancy from the time of diagnosis averages from two to five years.
The disease causes progressive wasting of muscles and leads to difficulties in speech, swallowing, mobility and even respiration. Cognitive function is typically spared.
The cause of ALS remains unknown, but what is clear is that for some unknown reason, there is a progressive failure of energy production of the motor neurons, the nerve cells that connect the brain to the muscles.