Research Spotlight: Type 1 Diabetes and Gluten

Gluten and the Microbiome

In humans, the relationship between type 1 diabetes and celiac disease is clear: having celiac disease dramatically increases risk for becoming a type 1 diabetic. But even beyond those with celiac disease, it has now been shown that early introduction of gluten-containing cereals in infancy is directly related to increased risk for type 1 diabetes.

The why and how of this relationship are still not perfectly clear. However, new research is focused on the role of dietary gluten in challenging the microbiome – the 100 trillion bacteria living within each of us – and how this paves the way for increased inflammation and autoimmunity, fundamental mechanisms in type 1 diabetes.

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