DHA_Supplement_List

Why DHA Remains on the Supplement List

Over the past 10 years, in the various books that I have written, there has been a persistent emphasis on the importance of DHA, an omega-3, in terms of brain health. DHA represents over 90% of all the omega-3, polyunsaturated fatty acids in the brain, and further, it’s 10 to 20% of all the brain’s fat. DHA is especially concentrated in the gray matter, and is also an important part of the cellular membrane of neurons. DHA also has an important role to play in the functioning and structure of mitochondria, the release of neurotransmitters, the expression of DNA, the creation of the myelin insulation around every neuron, the management of neuroinflammation, and even the growth and differentiation of brain cells.

DHA plays a particularly important role in the frontal lobes, allowing us to maintain executive function, pay attention to the various tasks in which we are engaged, and even plan for the future and solving problems. Continue reading

adhd_drug_parkinsons

ADHD Drugs Associated with a Dramatic Increased Risk for Parkinson’s

Estimates indicate that approximately 11% of school-aged children in United States have attention-deficit/ hyperactivity disorder (ADHD). Further, approximately 2/3 of these children are currently being medicated for this diagnosis. The most common medications are essentially stimulants like amphetamines or methylphenidates, including drugs like Adderall and Ritalin.

The areas of the brain that are potentially damaged or disrupted by these medications include the basal ganglia, brain structures that are involved in coordinated movement. The other area that is potentially involved is the cerebellum, which also plays a role in movement. Continue reading

empowering_neurologist_max_lugavere_perlmutter

The Empowering Neurologist – David Perlmutter, MD, and Max Lugavere


As we have talked about so many times in these pages, our lifestyle choices play a fundamental role in determining not just how our brain functions today, but its long-term destiny as well.

My good friend Max Lugavere became a globally-recognized citizen scientist, as it relates to brain degeneration, as a consequence of his mother’s battle with a neurodegenerative condition. In his new book, Genius Foods, Max details how he was basically left empty-handed at being able to do anything meaningful to help his mother in her battle. He visited many of our country’s most well-respected academic institutions and hospitals, and ultimately received nothing more than a list of meaningless medications. Continue reading

alcohol_for_brain_health

How Much Wine Should I Drink?

How much alcohol should we consume? We have all heard that there are health benefits associated with low level alcohol consumption, like drinking a glass or two of red wine each day. Indeed, I have made this suggestion in my blogs and in many of the books I have written. While we do know that alcohol is, in and of itself, toxic to nerve cells, the scientific literature would tell us that there is decreased risk of conditions like Alzheimer’s disease in individuals who consume small amounts of alcohol each day.

In a new study appearing in the journal Scientific Reports, researchers again attempted to unravel the facts as it relates to the beneficial effects of alcohol. Before you get put off by this study’s somewhat compelling (Beneficial effects of low alcohol exposure, but adverse effects of high alcohol intake on glymphatic function) title, allow me to explain. Continue reading

brain_inflammation_shrinkage

Inflammation Today Means Brain Shrinkage Tomorrow

As I have emphasized over the past decade, the fundamental mechanism that underlies neurodegenerative conditions, including Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, and other issues (think diabetes, coronary artery disease, and even cancer), is the process of inflammation. We’ve got to do everything we can in terms of our lifestyle choices to bring inflammation under control. Dietary choices like choosing to limit sugar and carbohydrates, avoiding gluten, eliminating vegetable oils (corn oil, sunflower oil), increasing intake of healthful fats (olive oil, avocado oil, nuts and seeds), and favoring fiber-rich foods, are all fundamental building blocks of a lifestyle that helps to reduce the risk for excess inflammation.

We know that there is a higher level of the chemicals that mediate inflammation in the blood of individuals with higher blood sugar, caused by many of the poor choices outlined above. Again, higher blood sugar correlates with higher levels of inflammation. Continue reading

exercise_BDNF_brain_function

Yes, A Magic Bullet for Your Brain

I have spoken at length about the importance of exercise for increasing the gene expression of BDNF, a protein that increases the growth of new brain cells. As previously mentioned, research has shown that people with higher levels of BDNF are at a lower risk of developing dementia.

In this new study, exercise in people age 50 or over is demonstrated to have significant effects on cognition. The report is a meta-analysis, meaning a review of other research publications (in this case, 39 studies). It’s a comprehensive look at how exercise impacts the brain!

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Diabetes, Obesity and Brain Health

Over the past several years I have been writing about the detrimental effects of type 2 diabetes on brain health. For example, we’ve seen an extensive amount of research published that shows a strong relationship between even subtle elevations of blood sugar and future risk for Alzheimer’s disease. In addition, we know that elevation of blood sugar is related to a reduction in size of the brain’s memory center, the hippocampus. As it turns out, this reduction is correlated with both a decline in cognitive function as well as mood disorders. Continue reading

Dr. Perlmutter on Dr. Oz, May 2014

Thursday on Dr. Oz: Dr. Perlmutter Reveals How Gluten Threatens Your Brain

Tomorrow (Thursday, May 8th) on the Dr. Oz Show, I’ll be discussing the very real threat that gluten poses to brain health and function. I’m actually going to bring along a patient whose life was pretty much destroyed by a devastating movement disorder that involved her face. Tune in to watch what happened to her when she went gluten-free!

Gluten induces inflammation, and this may well be happening in all humans! Inflammation is a pivotal mechanism involved in all brain degenerative disorders. I’ll demonstrate exactly how this happens, so tune in. Should be very instructive.

Find your local broadcast time and station.