childrens_brain_function

Helping Protect Our Children’s Brain Function for Their Later Years

There are a number of factors that are clearly associated with risk of dementia, and specifically Alzheimer’s disease-related dementia. For example, there’s a dramatic increase in risk of developing Alzheimer’s disease in people who have been diagnosed with type two diabetes. Sedentarity, meaning lack of physical activity, is also associated with increased risk as are early life stress, head trauma, and low educational level.

Research has also demonstrated a relationship of Alzheimer’s risk to childhood socioeconomic status as well as school performance.

But an important missing link in these studies that demonstrate associations is an actual demonstration, not of the cognitive impairment, but of actual physical changes that take place in the brain that may then relate to decline in the brain’s function. Continue reading

excess_fat_brain

How Does Excess Body Fat Threaten Memory?

In the past, I have written several blogs discussing the relationship of body measurements like body mass index (BMI) to cognitive function, as well as relationships between what is called the waist-to-hip ratio with atrophy of the brain. Another important relationship that we have explored extensively in the past is the connection between excess body fat and inflammation.

So, one might wonder if the mechanism whereby obesity relates to declining cognitive function, like worsening memory, may be mediated by inflammation. Basically, the question I am asking has to do with connecting these dots. Continue reading