It’s becoming quite common these days to see news releases documenting the failure of yet another experimental drug for the treatment of Alzheimer’s disease. In fact, one major pharmaceutical company, Pfizer, indicated in February of this year that they were no longer going to pursue efforts to develop a drug to treat this disease, which is now reaching epidemic proportions.
That said, millions of Americans are already taking medication that is FDA approved, to “treat” their Alzheimer’s disease. Since these medications are FDA approved, one would expect that they’ve been extensively tested and proven not only safe, but effective as well. Continue reading
I’ve often been quoted as stating that there is no pharmaceutical approach that has meaningful effectiveness on the treatment of Alzheimer’s disease. Unfortunately, I have to continue to make this claim. As was recently reported in the journal Neurology:
Despite great scientific efforts to find treatments for Alzheimer’s disease (AD), only 5 medications are marketed, with limited beneficial effects on symptoms, on a limited proportion of patients, without modification of disease course. The prevalence of AD doubles every 5 years reaching an alarming rate of 50% in those aged 85 years and older. In the context of the demographic trends of modern society, where the elderly are the fastest growing segment of the population, identification of new therapeutic targets that may prevent, delay, or cure AD is critically needed. (italics added).
The authors reemphasize what we know: that there is no silver bullet available now, or in the foreseeable future, that will help with this devastating and fatal condition. Continue reading
By: The Dr. Perlmutter Team
Alcohol is one of the most controversial topics health and wellness practitioners must navigate. Frequently, readers of this blog ask if alcohol consumption can be a part of a healthy lifestyle — my answer is, it depends.
Many studies have shown that alcohol consumption may have benefits far beyond easing social interaction and improving dance floor performance. A meta-analysis of the literature conducted in 2015 by the Journal of Internal Medicine found that moderate alcohol consumption is associated with reduced risk for coronary artery disease, stroke, and heart failure. However, that same study also found that heavy drinking, defined as consuming three or more standard-sized drinks per day, is associated with increased risk of high blood pressure, coronary artery disease, abnormalities in heart rhythm, and brain bleeding type stroke. How can alcohol consumption be associated with both an increased and decreased risk of coronary artery disease and stroke? Continue reading