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Sleep Duration and Cognitive Decline

By the Dr. Perlmutter Team

When asked what supplements I recommend for optimal health, I occasionally reply, “sleep.” Sleep is powerful on so many levels in terms of health outcomes. We know that sleep duration and quality impact inflammation, what and how much we eat, hormone balance, decision-making, mood states, and much more.

An interesting study on sleep recently appeared in one of the publications of the American Medical Association called JAMA Network Open. The researchers behind the study sought to investigate the association between sleep duration and cognitive decline. They analyzed data from 20,065 total participants in two cohort studies, one in the United Kingdom, The English Longitudinal Study of Ageing (ELSA), and one in China, the China Health and Retirement Longitudinal Study (CHARLS). The ELSA sample included people 50 years or older and the CHARLS sample included people 45 years or older. Continue reading

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Alzheimer’s Prevention Strategies Validated

Over the past decade we have been vigorously promoting the concept of Alzheimer’s prevention. Alzheimer’s disease is devastating, not just for the patient, but for families and loved ones as well. And let me be candid: watching my father succumb to Alzheimer’s was the most emotionally challenging experience of my life. Not only that, it also served to strengthen my resolve to do whatever I can to continue to raise awareness of the science that supports the notion that our lifestyle choices do indeed play an important role in determining our risk for this disease – a disease for which there is no meaningful treatment whatsoever. Continue reading

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The Empowering Neurologist – David Perlmutter, M.D. and Dr. Dale Bredesen


It’s exciting to watch new developments in medicine, especially when new treatments for diseases are developed. Unfortunately, there is no treatment that has any merit for Alzheimer’s disease. Think of it, this disease that affects close to 5.8 million Americans is a disease for which we have no meaningful treatment whatsoever.

As many of you know, Dr. Dale Bredesen has pioneered a novel approach to Alzheimer’s disease. Rather than offering up a single treatment, he has created a multi-pronged program that is proving successful in reversing this disease. Yes, I’ll repeat, this program has reversed Alzheimer’s disease. Continue reading

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Alzheimer’s and Exercise – You Can Protect Your Brain

The number of Americans diagnosed with Alzheimer’s disease has continued to grow at a dramatic rate. Currently, it is estimated that some 5.8 million Americans (of all ages) have Alzheimer’s disease. By and large, this is a disease of elderly individuals, with approximately 5.6 million of those diagnosed age 65 or older. To put that number into context, consider that this means 1 in 10 people age 65 or older suffers from Alzheimer’s disease. Further, it is instructive to note that there are some 200,000 individuals here in America under age 65 years who have also been given the diagnosis.

Despite heroic research efforts, Alzheimer’s remains a disease for which there is no cure or meaningful treatment whatsoever. That said, it is critical that we ask ourselves if there is any evidence that the disease could be prevented, or at least explore what could be done to lower one’s risk. Continue reading