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The Failure of Alzheimer’s Drugs

By anyone’s definition, we must now consider Alzheimer’s disease to be an epidemic. Alzheimer’s is a progressive degenerative neurological condition that actually has its origins decades before the initial symptoms of cognitive decline begin to appear. Unfortunately, by the time these symptoms of the disease emerge—memory loss, cognitive decline, and behavioral shifts—there is very little that can be done as, according to our most well-respected medical journals, there is currently no meaningful pharmaceutical treatment for this condition. Despite this reality, pharmaceutical companies continue to market “Alzheimer’s drugs” to the tune of some $3-4 billion annually. Continue reading

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Diabetes Risk and Impulsivity

Understanding the relationship between less healthful dietary and lifestyle choices and developing type-2 diabetes, a recent study linking the brain’s center for impulsive behavior and diabetes risk was really interesting.

The research was performed at the Massachusetts General Hospital and involved 232 non-diabetic subjects. These individuals underwent brain-imaging studies that measured the metabolic activity of their amygdalas, an area of the brain that is involved with fear, stress, and impulsivity.

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Simple Carbs Threaten the Brain

Today’s video takes a look at a subject that’s at the forefront of our discussion on this blog: how lifestyle choices can impact the fate of your brain. Specifically, we’re looking at how the lifestyle choices that can lead to the development of diabetes may also play a role in raising your risk for Alzheimer’s disease (remember, a disease for which there is no cure).

A new study, published in Frontiers in Aging Neuroscience, explores changes we see in brain energetics, or the brain’s ability to utilize fuel. Traditionally this is looked at considering glucose, or sugar, as a fuel source. Continue reading