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Body Fat Threatens Ability to Make Good Choices

How does excess body fat affect the brain? Over the past several years we have been describing the various mechanisms whereby body fat increases the production of the chemical mediators of inflammation, and how inflammation is the underpinning mechanism of brain degeneration like we see in Alzheimer’s disease and Parkinson’s. But beyond considering risk of these conditions, it’s worthwhile to gain some understanding as to how excess body fat might, moment to moment, affect how the brain is functioning. Continue reading

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What Makes Brain Wash Different

As I write you this post, we sit less than two months away from the release of my newest book, Brain Wash: Detox Your Mind for Clearer Thinking, Deeper Relationships, and Lasting Happiness, which I co-wrote with my son, Austin Perlmutter, MD. As we’ve been having more conversations about this book with friends, family, and this community, both Austin and I have come to appreciate that Brain Wash is a little bit different. 

Take, for instance, Grain Brain Whole Life Plan. This book provided extremely important information and lifestyle recommendations intended to help you live a longer and healthier life. These recommendations covered a wide array of categories, including exercise, diet, and stress reduction. But like so many books that are available these days, as well as online programs and health-related television shows, it’s one thing to receive this terrific information, but even the very best of information, like what we hope we portrayed in the Grain Brain Whole Life Plan,  is useless unless decisions are made to implement the recommendations. Continue reading

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Your Alzheimer’s Prevention Program – Start Today!

It’s relatively straightforward – the best time to do something about fending off Alzheimer’s disease and dementia is well before you start to experience warning signs of cognitive decline. As has been well-documented on this blog before, inflammation in your 20s, 30s, 40s…really, at any stage in life, has been associated with increasing your risk for Alzheimer’s disease, a disease for which there is no cure.

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Announcing Brain Wash

Look around and ask yourself, could things be better? We believe the answer is a resounding yes. And this is our ultimate goal in bringing out our new book, Brain Wash.

Brain Wash is a functional roadmap for understanding how so much of what characterizes our modern world influences our brains andmost importantly, our decision-making. From our modern diets to our lack of restorative sleep to our virtual addiction to our digital experiences, the trappings of modern times actually conspire to keep us unfulfilled, impulsive, and self-centered. Brain Wash begins by bringing these powerful influences into stark reality. We present a framework for appreciating the negative impact of these exposures, and then provide a set of practical interventions for reclaiming our brains and improving our physical and mental health.  Continue reading

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The Failure of Alzheimer’s Drugs

By anyone’s definition, we must now consider Alzheimer’s disease to be an epidemic. Alzheimer’s is a progressive degenerative neurological condition that actually has its origins decades before the initial symptoms of cognitive decline begin to appear. Unfortunately, by the time these symptoms of the disease emerge—memory loss, cognitive decline, and behavioral shifts—there is very little that can be done as, according to our most well-respected medical journals, there is currently no meaningful pharmaceutical treatment for this condition. Despite this reality, pharmaceutical companies continue to market “Alzheimer’s drugs” to the tune of some $3-4 billion annually. Continue reading

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Diabetes Risk and Impulsivity

Understanding the relationship between less healthful dietary and lifestyle choices and developing type-2 diabetes, a recent study linking the brain’s center for impulsive behavior and diabetes risk was really interesting.

The research was performed at the Massachusetts General Hospital and involved 232 non-diabetic subjects. These individuals underwent brain-imaging studies that measured the metabolic activity of their amygdalas, an area of the brain that is involved with fear, stress, and impulsivity.

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Grain-Fed vs Grass-Fed and Finished Beef – Why Does it Matter?

By the Dr. Perlmutter Team

Americans eat a lot of meat. In 2018, the United States Department of Agriculture projected that the average person would consume over two hundred pounds of chicken, pork, and beef by year’s end. That’s more than half a pound daily per capita, every day of the year! While it is possible to consume an omnivorous diet and maintain a healthy lifestyle, we recommend viewing meat as a garnish or side dish rather than the focus of your meal. The perfect plate is full of colorful, above-ground leafy vegetables and healthy fats, and if you choose to eat meat, then a three-to-four ounce serving of meat. However, it’s very important to remember that not all meat is created equally.

One of the most important factors in determining the overall quality of meat—especially red meat—is the dietary patterns of the livestock that produced it. When you think about it, this makes perfect sense: the food an animal consumes is used by their body to grow and develop, and, ultimately, becomes the very food that we consume. Feeding cattle a nutrient-poor diet will, in turn, produce a nutrient-poor food source, compared to cattle fed a natural, nutritious diet.

As it turns out, the age-old adage “You are what you eat” applies to cattle, too! Continue reading

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Benefits of Probiotics for your Mood, Gut, and Immune System

By: The Dr. Perlmutter Team

One of the most exciting developments in lifestyle science over the last decade has been the sharpening focus on the central role that our resident microbes (bacteria) play in regulating overall health. These microbes, together with their genetic material and metabolic byproducts make up what is collectively known as the microbiome. It is becoming readily apparent that the trillions of microbes living on and within us play a fundamental role in almost all of the systems of the body. Even as recently as 10-20 years ago, we did not understand the extent to which the gut microbiome can influence a person’s mood, regulate appetite, produce essential vitamins, regulate the immune system, and influence systemic inflammation.

There is even evidence to suggest that the microbiome affects us on such a fundamental level that it can regulate the expression of our DNA! Continue reading