Lately, in an apparent attempt to push back from the negativity surrounding high fructose corn syrup, there seems to be an increase in the number of articles published touting the advantages of fructose as a “safer sugar.” The main point that is so often emphasized is that unlike glucose, fructose does not seem to increase insulin. Increasing insulin, which is how our bodies cope with increased glucose levels, may, when it’s constantly challenged, lead to a state in which we tend to lose our sensitivity to insulin. This means that with time, on a diet that constantly raises our glucose levels, insulin becomes less effective. Losing insulin sensitivity or becoming “insulin resistant” is not only associated with elevated blood sugar and subsequent diabetes, but also a fairly extensive list of chronic degenerative conditions that we want to do our best to avoid like coronary artery disease and Alzheimer’s. Continue reading
It is well-documented that the accumulation of the beta-amyloid protein in the brain is correlated with Alzheimer’s disease. Ongoing research seeks to understand how, and at what stage of Alzheimer’s, beta-amyloid proteins influence the disease. Continue reading
Understanding the relationship between less healthful dietary and lifestyle choices and developing type-2 diabetes, a recent study linking the brain’s center for impulsive behavior and diabetes risk was really interesting.
The research was performed at the Massachusetts General Hospital and involved 232 non-diabetic subjects. These individuals underwent brain-imaging studies that measured the metabolic activity of their amygdalas, an area of the brain that is involved with fear, stress, and impulsivity.
So much has been written over the years extolling the health benefits of green tea. Green tea has been reported to be effective for weight loss, antioxidant effects, reducing risk of cancer, protecting the brain from Parkinson’s disease and Alzheimer’s, reducing risk of heart attack, and even for helping a person live longer. As it turns out, there is a fair amount of validation supporting many of these health claims. In fact, as it relates to living longer, one very extensive Japanese study involving 40,000+ adults over 11 years, shows that those individuals who drank 5 cups of green tea or more each day saw their risk of death reduced by 23%, for women, and 12%, for men.
As you might expect, I am especially interested in research related to brain health and functionality. As such, I was extremely interested in a recent publication that evaluated one component in green tea that shows high biological activity. The chemical, epigallocatechin-3-galate, better known as EGCG, has been long known as being one of green tea’s components most responsible for its reported health benefits Continue reading
Today’s video takes a look at a subject that’s at the forefront of our discussion on this blog: how lifestyle choices can impact the fate of your brain. Specifically, we’re looking at how the lifestyle choices that can lead to the development of diabetes may also play a role in raising your risk for Alzheimer’s disease (remember, a disease for which there is no cure).
A new study, published in Frontiers in Aging Neuroscience, explores changes we see in brain energetics, or the brain’s ability to utilize fuel. Traditionally this is looked at considering glucose, or sugar, as a fuel source. Continue reading
There is an extensive body of research that reveals how critical glucose uptake and utilization are for many types of cancer. What the research has been unable to determine is exactly how cancer cells might manipulate their environment so as to increase the availability of glucose.
We commonly think that if something is good for our health, that more of it is even better, right? More kale never hurt anyone. Putting on extra sunscreen may not protect us from even more UV rays, but it certainly won’t cause excess damage!
But is that actually always true? How about with insulin, which we’re commonly told to keep as low as possible? Continue reading
Energy medicine is now front-and-center as a major consideration in trying to unravel the mechanisms underlying Alzheimer’s disease. It’s now clear that a disruption of cellular energetics is fundamentally involved in the disease.
Multiple research studies have demonstrated that a decline in brain metabolism, specifically the brain’s utilization of glucose, is seen long before there are any clinical manifestations of Alzheimer’s disease. In other words, the first observable event in Alzheimer’s is the finding of reduced brain glucose utilization on a special type of brain scan. This observation presages the clinical manifestations like declining memory, judgment, and executive function by as much as several decades.
Why the brain suffers from this decline in its ability to use glucose as a fuel remains undefined, but new research is making the case that the hormone insulin is playing an important role in this event.