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The Empowering Neurologist – David Perlmutter, M.D. and Dr. Caroline Leaf

Our world today has certainly become far more chaotic than we had anticipated. As such, it becomes challenging to avoid toxic threatening thoughts and downstream manifestations like depression or anxiety. As our guest today makes clear, we don’t have to settle into this mental mess as if it is just our “new normal.” There is hope and there is help available to us, and the road to healthier thoughts and more happiness may actually be shorter than we think. Continue reading

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Exercise and Mental Health

By Dr. Austin Perlmutter

It’s not news to anyone: exercise is good for our health. What is more interesting is the recent research showing how physical activity may activate certain pathways within our immune systems, our endocrine systems, and even change our brain function. One fascinating area where all of this intersects is the link between exercise and mental health.

Mental health issues are a growing problem in the United States and worldwide. Depression alone affects around 350 million people and is one of the leading causes of disability across the planet. Despite the best efforts of providers and scientists, strategies for treating and preventing depression have been lacking. Many people continue to struggle with the condition even after receiving therapy. This is why it is so important that we continue to look for additional strategies in depression prevention and management. Of these, exercise is among the most promising. Continue reading

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Can A Ketogenic Diet Treat Mental Disorders?

By the Dr. Perlmutter Team

The ketogenic diet appears often in content I share as it offers a host of health benefits for conditions including Alzheimer’s disease, epilepsy, Parkinson’s disease, diabetes, and more. That list may now include mental disorders. As I recently discussed with Dr. Uma Naidoo, nutritional psychiatry is centered on how food affects mental health. While dietary interventions are known to serve multiple preventive and therapeutic roles in human health, it is exciting that there is a burgeoning field focusing specifically on how nutrition impacts mental disorders, especially in these challenging times.

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diet_depression

Diet and Depression: An Updated Perspective

By Dr. Austin Perlmutter

In conventional medical practice, the connection between diet and mood seems barely, if ever, mentioned. Depression is deemed a disease of the mind, or of the brain, treatable with psychotherapy or potent pharmaceuticals. In the latter, the focus seems primarily on modulating neurotransmitters like dopamine, serotonin, and norepinephrine.

Yet in the last several decades, there’s also been a push to revitalize dietary interventions for mood, especially for depression. Some have advocated strongly that food-based therapy is the solution to most health issues including mood disorders. But what does the current research in this field actually say, and are we interpreting it correctly? Continue reading

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The Empowering Neurologist – David Perlmutter, M.D., and Dr. Uma Naidoo


What an exciting and important presentation we have for you today. For many years we have been providing information focused on the pivotal role of nutritional choices as they relate to the brain, mostly in the context of neurodegenerative conditions like Alzheimer’s disease. Today, we’re going to explore how our nutritional choices actually impact us from a mood perspective with our very special guest, Dr. Uma Naidoo. Let me tell you a bit more about her.

Michelin-starred chef David Bouley described Dr. Uma Naidoo as the world’s first “triple threat” in the food as medicine space: She is a Harvard-trained psychiatrist, professional chef who graduated with her culinary schools’ most coveted award, and a nutrition specialist. Her niche work is in Nutritional Psychiatry and she is regarded both nationally and internationally as a medical pioneer in this field.

In her role as a Clinical Scientist, Dr. Naidoo founded and directs the first hospital-based clinical service in Nutritional Psychiatry in the USA. She is the Director of Nutritional and Lifestyle Psychiatry at Massachusetts General Hospital (MGH) & Director of Nutritional Psychiatry at the Massachusetts General Hospital Academy while serving on the faculty at Harvard Medical School.

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The Empowering Neurologist: Psychedelics & Psychotherapy – David Perlmutter, M.D. and Dr. Ingmar Gorman


Integration Psychotherapy, pioneered by our guest, Dr. Ingmar Gorman, is a fascinating technique that brings a powerful level of therapeutic efficacy to the use of psychedelics. Psychedelic experiences are certainly becoming more available, and what we learn today is how fundamentally important it is to appropriately process these experiences after they have occurred. So much literature is being published describing the efficacy of psychedelic compounds in the treatment of things like PTSD and refractory depression, but as Dr. Gorman makes clear, it’s not just the taking of the medicine that fully allows realization of improvement. Equally important is the post-experience therapy that helps frame and contextualize what the psychedelic experience has presented. Continue reading

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3 Ways to Care for Your Brain in a Pandemic

By Dr. Austin Perlmutter

In the wake of the global spread of the 2019 coronavirus (COVID-19), many of us have started to think more carefully about our health. How can we reduce our risk of infection and of infecting others? How can we improve our immune function? What might the virus do to our lungs, heart and blood vessels? But while these questions are very important, it’s also critical to consider how a pandemic affects our brains and how to guard them against this damage. Specifically, we need to be considering strategies to protect our mental and cognitive health.

We’ve long known that mental health suffers in periods of high stress. So it’s no surprise that the current pandemic has been linked to a spike in feelings of anxiety and depression. A troubling May 2020 survey reported that over 34% of Americans are now experiencing these symptoms. This comes at a time when the world is already experiencing an epidemic of mental illness. Continue reading