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Early Life Cigarette Smoke Exposure and Future Weight Gain

With ever increasing rates of overweight and obesity in America, we see, almost in lockstep, increasing rates of diseases that are linked to weight gain. Likely, mostly for cosmetic reasons, weight loss programs are proliferating at a record pace. And, truth be known, most weight loss programs, with strict adherence, will lead to weight loss, despite how they may vary in the diets that are recommended. While this challenges the notion as to what type of diet should be recommended for weight loss, it begs the question as to what gets people into trouble as it relates to weight gain in the first place.

It seems clear that there is a relationship between high consumption of refined carbohydrates and risk for weight gain. And for sure, other issues that are not specifically related to the types of foods people consume also have an impact on weight gain including things like sleep and exercise. But in this blog, I would like to consider new research that reveals how exposure to cigarette smoking from parent to child sets that child up for weight gain later in life. Continue reading

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COVID-19 Isn’t Random

One of the common statements often repeated in the media about COVID-19 is that it is seemingly random in terms of both getting the virus and having a poor outcome. But, upon further inspection, that’s not what the actual science is revealing. As we move deeper into our involvement with this virus some important patterns are emerging that make it quite clear that COVID-19 does indeed discriminate.

In a recent article, Dr. Austin Perlmutter explored how COVID-19 is actually an “opportunistic infection,” meaning that it takes advantage of patients whose immune systems are not functioning optimally. In the past we would have considered less than optimal immune function to be a characteristic of people who have had, for example, chemotherapy or radiation treatment, exposure to immune-suppressing medications after organ transplantation, or a diagnosed autoimmune disease. But as Dr. Austin Perlmutter has made clear, we now need to broaden our scope and embrace the notion that so many of our most common degenerative conditions, from diabetes to obesity, actually compromise immune function and allow the SARS-CoV-2 virus the opportunity to do its dirty work. Continue reading

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Cancer Risk – Why Blood Sugar Matters

By: The Dr. Perlmutter Team

Blood sugar elevation has become a central focus in medicine these days because of its well-established relationship to so many chronic conditions including Alzheimer’s, diabetes, obesity, and Parkinson’s. Now, new research reveals that there may well be a relationship to cancer risk as well.

Researchers at Johns Hopkins and Yonsei University in Seoul, Korea were interested in exploring possible relationships between blood sugar levels and risk for developing cancer. They studied a sample of over 1 million Koreans between the ages of 30 and 95 who had either a positive cancer diagnosis or had died of cancer. Their findings, published in the Journal of the American Medical Association, are quite remarkable and certainly instructive. Continue reading

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How Does Excess Body Fat Threaten Memory?

In the past, I have written several blogs discussing the relationship of body measurements like body mass index (BMI) to cognitive function, as well as relationships between what is called the waist-to-hip ratio with atrophy of the brain. Another important relationship that we have explored extensively in the past is the connection between excess body fat and inflammation.

So, one might wonder if the mechanism whereby obesity relates to declining cognitive function, like worsening memory, may be mediated by inflammation. Basically, the question I am asking has to do with connecting these dots. Continue reading