The science surrounding the ketogenic diet expands day by day. In today’s video I will explore some of the science that shows a relationship between the ketogenic diet and increased brain glutathione levels, and explain why that matters for brain health. The full study can be found here. Continue reading
So much has been written over the years extolling the health benefits of green tea. Green tea has been reported to be effective for weight loss, antioxidant effects, reducing risk of cancer, protecting the brain from Parkinson’s disease and Alzheimer’s, reducing risk of heart attack, and even for helping a person live longer. As it turns out, there is a fair amount of validation supporting many of these health claims. In fact, as it relates to living longer, one very extensive Japanese study involving 40,000+ adults over 11 years, shows that those individuals who drank 5 cups of green tea or more each day saw their risk of death reduced by 23%, for women, and 12%, for men.
As you might expect, I am especially interested in research related to brain health and functionality. As such, I was extremely interested in a recent publication that evaluated one component in green tea that shows high biological activity. The chemical, epigallocatechin-3-galate, better known as EGCG, has been long known as being one of green tea’s components most responsible for its reported health benefits Continue reading
Estimates indicate that approximately 11% of school-aged children in United States have attention-deficit/ hyperactivity disorder (ADHD). Further, approximately 2/3 of these children are currently being medicated for this diagnosis. The most common medications are essentially stimulants like amphetamines or methylphenidates, including drugs like Adderall and Ritalin.
The areas of the brain that are potentially damaged or disrupted by these medications include the basal ganglia, brain structures that are involved in coordinated movement. The other area that is potentially involved is the cerebellum, which also plays a role in movement. Continue reading
As I’m sure you’re aware, we spend a lot of time in this forum discussing how the health of the brain is impacted by the health of the gut, the gut-brain connection. Made clear by the latest science, this is a powerful relationship that has ramifications which affect our risk for myriad number of diseases, including Alzheimer’s, a disease for which there is no cure.
While there certainly are various medications that prove somewhat helpful in the treatment of symptoms associated with Parkinson’s disease, it’s important to recognize that these medications are not actually treating the underlying disease itself.
We now understand that one of the pivotal mechanisms in Parkinson’s disease is the compromise of energy production at the mitochondrial level. This ultimately manifests as various problems, not just in the brain but throughout the entire body. With this understanding, specifically targeting mitochondrial function makes sense as a way of addressing this fundamental and underlying abnormality in Parkinson’s. Continue reading
As we have explored previously, elevated blood sugar is clearly toxic for the brain. Higher blood sugar is clearly a risk for Alzheimer’s disease, along with coronary artery disease, diabetes, and even cancer.
But focusing on the brain, I think it’s important to emphasize that elevated blood sugar has wide-ranging negative effects on brain cells and their functionality. Elevated blood sugar is associated with inflammation, and this is a cornerstone mechanism across a wide spectrum of neurodegenerative conditions, including Alzheimer’s disease and Parkinson’s disease. In addition, persistent elevation of blood sugar ultimately compromises the function of the hormone insulin. We now recognize that insulin is important for the health and integrity of the brain not only because of its role in allowing glucose to be used as fuel, but also how it functions as a nurturing hormone. Continue reading
Without a doubt, we spend a lot of time in this forum discussing the influence of bacteria on the health of the gut, and how that translates into risk for disease elsewhere in the body. As it turns out, there are a multitude of other entities residing within the gut that are absolutely worthy of our attention.
Bacteriophages are a type of virus that can infect bacteria and alter their function. First identified in 1917, bacteriophages have been long overlooked in terms of their potential contribution to human disease.
Our interview today is with Dr. George Tetz, one of the world leaders in bacteriophage research. He has identified pathways whereby bacteriophages can alter gut bacteria in such a way so as to modify their function in the human body. His work relates bacteriophage activity with autoimmune conditions, like Type 1 diabetes. He has also found strong connections between bacteriophages and Parkinson’s disease, a subject into which he’ll dive deeper in our discussion. He believes that these bacteria-infecting viruses may also play a prominent role in other neurodegenerative conditions, including amyotrophic lateral sclerosis (ALS) and even Alzheimer’s disease.
The implications of the science shared in this interview are many! I will state at the outset that some of the discussion is at a level that might be challenging for the non-researcher to understand, but there are some terrific takeaways and I would urge all of you to celebrate with me the accomplishments of this incredible scientist.
Finally, I mention a YouTube video that graphically illustrates the function of these bacteriophages. It’s very well-done, and worth a look.
By: The Dr. Perlmutter Team
The ketogenic diet has taken health circles by storm. Everyone seems to know somebody who has “gone keto” or is at least thinking about it. Keto labels are popping up on restaurant menus and in grocery stores.
And yet, the 2018 U.S. News & World Report recently evaluated 40 diets and guess which diet came in dead last? The ketogenic diet.
What is going on here? How can a diet land in two polar opposite camps? In a world that seems to thrive on polarizing controversy, let’s put a few misconceptions to rest and take a look into the effects of the ketogenic diet on the body. Because there is no doubt about it – the benefits of a ketogenic diet are profound. Continue reading