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The Empowering Neurologist – David Perlmutter, M.D. and Dr. Elissa Epel

How well we age is actually something we can control. We are learning more and more that there are correlations between our “aging,” in other words how long we remain healthy versus suffering from some form of chronic disease, and the length of the ends of our DNA called telomeres. Certainly, the idea of “lengthening your telomeres” is so much a part of the public discussion that products are using this as a catchphrase for marketing.

So I think it’s important to bring this whole notion of telomeres as markers of disease risk and perhaps more importantly as playing a mechanistic role in aging to a better level of understanding. Continue reading

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The Empowering Neurologist – David Perlmutter, M.D. and Dr. James DiNicolantonio


These days, probably the number one topic of conversation in the health world is immunity. Never has our dependence on a healthy immune system been so obvious. So, it’s very timely that Dr. James DiNicolantonio has published his new book, The Immunity Fix.

The Immunity Fix explores, first, the notion that we can have a huge impact on the functionality of our immune systems based on the choices we make every day. He talks about the fundamental role of nutrition and especially the threat of deficiency of various trace minerals like magnesium and others, as well as how we should go about repleting our deficiencies. Beyond minerals, he describes how to use other, more exotic nutritional supplements appropriately to augment immune function and why the balance of immune function is particularly relevant in COVID-19. Continue reading

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The Empowering Neurologist – David Perlmutter, M.D. and Dr. Caroline Leaf

Our world today has certainly become far more chaotic than we had anticipated. As such, it becomes challenging to avoid toxic threatening thoughts and downstream manifestations like depression or anxiety. As our guest today makes clear, we don’t have to settle into this mental mess as if it is just our “new normal.” There is hope and there is help available to us, and the road to healthier thoughts and more happiness may actually be shorter than we think. Continue reading

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The Empowering Neurologist – David Perlmutter, M.D. and Dr. Daniel Amen


Your brain is always listening and responding to an incredibly large number of hidden influences, and unless you recognize and deal with them, they can steal your happiness, spoil your relationships, and sabotage your health. My good friend Dr. Daniel Amen calls these influences “dragons” in his new book Your Brain Is Always Listeningand with good reason as he explains. Importantly, this book will teach you to tame the dragons and regain what, for many, has been so elusive, especially these days. Continue reading

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The Empowering Neurologist – David Perlmutter M.D., and Sergey Young

There’s a lot going on in the area of longevity science. Researchers are hard at work trying to unravel the mysteries of what causes the disease we know as aging.

But beyond the actual bench research, dedicated thought leaders are doing their part to facilitate the science and bring attention to this burgeoning discipline. And one of the pivotal players in this arena is my good friend, Sergey Young. Continue reading

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The Empowering Neurologist – David Perlmutter M.D., and Dr. Alan Gaby

Some 30 years ago I had the opportunity to attend a medical conference and heard a presentation by Dr. Alan Gaby. Truthfully, this event marked a turning point in my career destiny for reasons that we will touch upon in this interview. But suffice it to say that I have a great deal of gratitude in my heart for the dedication to the art of medicine that so characterizes Dr. Gaby’s efforts over so many productive years. 

Dr. Alan Gaby received his undergraduate degree from Yale University, his M.S. in biochemistry from Emory University, and his M.D. from the University of Maryland. He was in private practice for 19 years, specializing in nutritional medicine. During that time he developed a wide spectrum of innovations that remain in widespread use today.

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The Empowering Neurologist – David Perlmutter, M.D. and Dr. Kari Nadeau

Food allergies are an ever increasing problem in our world. And the problem can be life-threatening, and certainly life-changing for as many as 11% of our population. This is why I wanted to bring on the program a world leader on the topic of food allergy who could explain to us exactly what food allergies are all about in terms of their causation, their increasing prevalence, how to handle them on a day-to-day basis, and what the future looks like in terms of developing therapies.

Our program today is with Kari Nadeau, MD, PhD, author of the terrific book The End of Food Allergy. Continue reading

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The Empowering Neurologist – David Perlmutter M.D., and Dr. David Sinclair

Fair to say that we all assume that aging is inevitable. In reality however, there is no biological law that says we must age. Over the years we’ve seen a variety of theories proposed to explain why we age including the accumulation of damage to our DNA, the damaging effects of chemicals called “free radicals,” changes in the function of our mitochondria, and so many others.

Our guest today, Dr. David Sinclair, believes that aging is related to a breakdown of information. Specifically, he describes how, with time, our epigenome accumulates changes that have powerful downstream effects on the way our DNA functions. Reducing these changes to the epigenome is achievable and in fact, even taking it further, his research now reveals that the epigenome can be reprogrammed back to a youthful state. Continue reading

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The Empowering Neurologist – David Perlmutter M.D., and Wim Hof

Holy Toledo! Did yours truly just have an amazing interview? You bet. I spoke with Wim Hof, a.k.a. “The Iceman.” Wim holds 26 world records for his feats of endurance and exposure to cold―such as climbing Mount Kilimanjaro wearing only shorts and shoes, running a barefoot half-marathon in the Arctic Circle, and standing in an ice-filled container for more than 112 minutes. On March 16, 2000, Hof set the Guinness World Record for farthest swim under ice, with a distance of 57.5 meters (188.6 ft).

Having been taught by the majestic natural power of the cold exposure coupled with a unique breathing technique, Wim is on a mission to share his discoveries with the world. Continue reading