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The Empowering Neurologist – David Perlmutter, MD, and Dr. Matthew Phillips

While there certainly are various medications that prove somewhat helpful in the treatment of symptoms associated with Parkinson’s disease, it’s important to recognize that these medications are not actually treating the underlying disease itself.

We now understand that one of the pivotal mechanisms in Parkinson’s disease is the compromise of energy production at the mitochondrial level. This ultimately manifests as various problems, not just in the brain but throughout the entire body. With this understanding, specifically targeting mitochondrial function makes sense as a way of addressing this fundamental and underlying abnormality in Parkinson’s. Continue reading

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The Empowering Neurologist – David Perlmutter, MD and Dr. James DiNicolantonio

Without question one of the most common recommendations made when adults visit a medical practitioner is to reduce their sodium consumption. We’ve all been led to believe that salt is about the worst food additive out there and that it will make everybody hypertensive and affect heart and kidney functioning as well.

But much like the castigation of saturated fat, there is another side of this story we’re just now learning. Dietary sodium may have some very important positive attributes. Sodium, it turns out, it is important for the function of the hormone insulin and as such, deficiencies of sodium may relate to diabetes. Other problems that may be associated with not consuming enough salt include sleep dysfunction, poor energy, loss of mental focus, declining athletic performance, and even poor sexual performance.

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The Empowering Neurologist – David Perlmutter, MD, and Dr. Will Cole


When Grain Brain first hit shelves, one of the first questions I started to hear repeated to me again and again was “This is great and all, but what can I do if I’m a vegetarian?” The answer is simple: you can be a vegetarian and follow the Grain Brain lifestyle, no problem (and if you want to learn more about this, visit our vegan/vegetarian focus page).

Now as similar lifestyles begin to take the spotlight, the ketogenic lifestyle chief among them, the same question, posed about these diets, are coming to the fore. Thankfully, Dr. Will Cole is here to help. Continue reading

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The Empowering Neurologist – David Perlmutter, MD and Dr. George Tetz

Without a doubt, we spend a lot of time in this forum discussing the influence of bacteria on the health of the gut, and how that translates into risk for disease elsewhere in the body. As it turns out, there are a multitude of other entities residing within the gut that are absolutely worthy of our attention.

Bacteriophages are a type of virus that can infect bacteria and alter their function. First identified in 1917, bacteriophages have been long overlooked in terms of their potential contribution to human disease.

Our interview today is with Dr. George Tetz, one of the world leaders in bacteriophage research. He has identified pathways whereby bacteriophages can alter gut bacteria in such a way so as to modify their function in the human body. His work relates bacteriophage activity with autoimmune conditions, like Type 1 diabetes. He has also found strong connections between bacteriophages and Parkinson’s disease, a subject into which he’ll dive deeper in our discussion. He believes that these bacteria-infecting viruses may also play a prominent role in other neurodegenerative conditions, including amyotrophic lateral sclerosis (ALS) and even Alzheimer’s disease.

The implications of the science shared in this interview are many! I will state at the outset that some of the discussion is at a level that might be challenging for the non-researcher to understand, but there are some terrific takeaways and I would urge all of you to celebrate with me the accomplishments of this incredible scientist.

Finally, I mention a YouTube video that graphically illustrates the function of these bacteriophages. It’s very well-done, and worth a look.

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The Empowering Neurologist – David Perlmutter, MD, and Melissa Schilling


Last year I had the opportunity to interview professor Melissa Schilling on the topic of diabetes and Alzheimer’s disease, in reference to her publication in the Journal of Alzheimer’s Disease.

I find it very fascinating that her research and publication are really quite unrelated, seemingly, to her profession as Professor of Management at New York University Stern School of Business.

That said, as yet another manifestation that Prof. Schilling is truly a renaissance person, her new book, Quirky, explores the characteristics of some of the most incredible innovators who have changed the destiny of the world.

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The Empowering Neurologist – David Perlmutter, MD, and Dr. Michael Ruscio

Recently, at the annual PaleoFX conference, I had the opportunity to sit on a panel alongside Dr. Michael Ruscio. I was extremely taken by his interaction with the audience, the compassion (and information) in his message, and the depth of his knowledge.

I was delighted when he sent me his new book, Healthy Gut Healthy Youand I have found this book to be both extremely comprehensive and written in a user-friendly way. He has done an incredible job in writing this book and I’m hoping you will find it as interesting as have I once you’ve had a chance to read your copy. Continue reading

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The Empowering Neurologist – David Perlmutter, MD and Magdalena Wszelaki

Hormone imbalance is extremely common, and generally it is treated with pharmaceutical interventions. Why don’t we take a step back for moment and ask ourselves just why these issues are occurring in the first place?

Once we do that, all roads seem to point us towards an investigation into how our lifestyle choices may be impacting our health, specifically the balance of our hormones. Further, some of the most important lifestyle choices we make are the foods we choose to consume. Continue reading

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The Empowering Neurologist – David Perlmutter, MD and Dr. Whitney Bowe


I am hopeful that, at this stage of the game, it will not come as a total surprise that even the health and appearance of our skin is affected by microbes and the microbiome.

Many of us grew up at a time when bacteria were universally considered to be detrimental and and therefore were the targets of therapies to treat specific conditions. Acne, for example, was considered to be a disease caused by the action of a bad bacterium which was then targeted with topical and oral antibiotics, as well as various other skin sanitizing techniques. Unfortunately, to a significant degree, this mentality remains pervasive. Continue reading