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Category: Brain Maker

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AGEs and Leaky Gut

A variety of factors conspire to lead to leakiness of the gut and this plays a fundamental role in inflammation. We know that, for example, things like stress and environmental toxins can lead to leakiness of the gut. However, we now understand that AGEs (Advanced Glycation End Products), which are proteins bound to sugar when blood sugar is chronically elevated, also play a role in increasing gut permeability. In this video we explore this further.

  • Janet

    I would like to express my gratitude to you, Dr. Perlmutter, for sharing this information with us. Please continue. I find it very interesting.

    • David Perlmutter

      I will continue to share these videos with you Janet.

    • Peter

      I second that. Thanks, doc!

  • Denise C.

    Thank you for this video. I wonder what can be done to reverse leaky gut once it develops, and how long it can take. Thank you so much for any advice. Denise

    • David Perlmutter

      Brain Maker is going to cover that in great detail.

  • Gwen Robertson

    Thank you Dr. Perimutter for this video. I lost my Mother to Alzheimer’s and, although I know I eat better than she did, I don’t want to end up like she did.

    • David Perlmutter

      Hope this video can help you on the road to optimal health.

  • Nik

    Thanks for the interesting video.
    What would you recommend for someone with type one diabetes?
    Our son has type one and his a1c runs between six and seven.
    I find it hard to get it lower than six.

    Long term what do you think this means for him?
    He is eleven now.

    • Sandy Bahr

      Many type one’s are successful at lowering A1c by use of the ketogenic diet. Look into it. Charlie Foundation has lots of good recipes for kids!

  • velevetcricket515

    My Mother died of Alzheimers. My Father died of a massive heart attack at age 66. I am a healthy 60 year old female. I have been on a dose of 40mg of a statin for for about seven years. After listening and reading your information I want to go off of my statin. Wish me luck

  • Lynn Dell

    This shows why modern wheat packs a one-two punch in the gut. The wheat starch, and the gliadin both contribute to a leaky gut. Gliadin, directly, and wheat starch, indirectly as it spikes blood sugar, which fuels the formation of advanced glycation end products.

  • Sue

    Do you have ideas on how to get rid of tinnitus?

  • julie

    Yes. I had ringing in the ears bad. Mine even interfered with being able to concentrate and sleep. I use u.s. grade therapeutic essential oil of frankensis on the bone behind the year. It helps a lot. I get my therapeutic essential oil of frankensis from a supplier that doesn’t water their oils down like many do. Bulkapatheocary is where I get mine…

  • julie

    Make sure its the u.s. blend therapeutic essential oil of Frankensis you get if you try it for your ringing in the ears. Apply a couple drops and rub onto the bone behind your ear.. doing this I got peace and quiet for a change after 4 years of irritating ringing that kept getting worse…

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