facebook pixel

Statin Drugs & Diabetes: What You Need To Know

Recent reports continue to find an adverse relationship between Type 2 diabetes and the risk of Alzheimer’s, with diabetes shown to increase the risk of an Alzheimer’s disease diagnosis.

In light of this, it would make sense that we do everything we can to prevent the development of diabetes in our own bodies. That’s why it’s troubling to hear about new research that demonstrates that one of the most commonly prescribed classes of medications, statin drugs (used to lower cholesterol), has a profound impact on the chance that someone could develop Type 2 diabetes. Let’s dive into this research today.

And once you’re down, hope over to the Articles section of my website, where you can find some links to more of my writings about statin drugs.

You can download a transcript of this video here.

Share this post

  • John Mott

    Interesting. But you don’t discuss the dosage taken and how that impacts the risk! Seems the study indicates much lower risk if dosage below 20mg. Can you give more detail on what study may say about relative dosage amounts?

    • Michael Brown

      It did show 10-20 versus 40-80. It was probably not considered significant between 10 and 20 or 40 and 80. That does not mean that there is no difference but the difference would be much less than between the to major groups. This smaller difference might not be statistically significant or considered not to be worth doing because of the smaller differences.

  • Bill Peche

    Would Red Yeast Rice Extract have the same effect? According to WebMD (http://www.webmd.com/cholesterol-management/red-yeast-rice#1), “One of the most important ingredients in RYRE is monacolin K. It’s also known as lovastatin, the active ingredient in the prescription drug Mevacor.

    • I’d like to know the same thing, or if phytosterols might be a safer non-pharmaceutical option.

    • HoneyJ

      RYRE has side effects same as statin drugs. A better choice would be to take vit. B3 and or garlic if you feel you need to lower your cholesterol. Lowering your cholesterol too low can be damaging to your overall health.

  • AnnieLaurie Burke

    Why are we still obsessed with lowering cholesterol, given the poor correlation between cholesterol levels and heart disease? In fact, for people over 65, several studies across many countries have shown a positive correlation between higher cholesterol and lower all-cause mortality.

  • Eve

    okay so what can you do to counteract the effects of statins if you have no option but to take the drugs?

  • Michael Brown

    What if the people that were on statin drugs were predisposed to diabetes based on the same factors that caused them to take the statin drugs in the first place? It seems a study would have to take a population and put half on statin, and half on a placebo to have a reliable result rather than looking at people that are already on statin versus those who don’t need them.

    • Greg McGrew

      I see your point, however it seems as though if part A( being in a position to need a the statin in the first place) and part B (choosing to take the drug). Are corollary and not causational, either way I think the take home messsage is not to get to part A in the beginning.

      But I do agree for the sake of science further understanding it wouldn’t be a bad idea

      • Emmalee

        Greg….My Mom and all her siblings had high cholesterol. None were diabetic. All were at a healthy weight. I have 4 siblings……I am the only one with cholesterol issues. We need to look at the genetic issues as well. My Mom passed away in September at age 90. She ate a healthy diet and exercised regularly. I started on Simvastatin in 2004…..healthy weight and exercised. I take fish oil and Vitamins E and D along with multivitamin and super probiotic. I was diagnosed with celiac disease in 1991 and got my RN degree in 1992 as a returning adult student.

        • Greg McGrew

          Great point. At the end of the day some may have a genetic disposition slightly offsetting their homeostasis apart from lifestyle

    • Matt

      The study says “statin therapy was associated with a 46% increased risk of type 2 diabetes after adjustment for confounding factors”. So I believe they have tried to account for this in their models. You are right it is still only an epidemiological study though, a double blind placebo controlled study would be nice!

  • Cliff

    I understand that Vitamin B3 (niacin) can possibly help with dementia/depression, while lowering LDL, Triglycerides & raising HDL… without the terrible side effects of statins. I’d be interested in Dr Perlmutter’s opinion on the pros/cons of this supplement (or, of course, any other reader.

  • Jack Morgan

    I am wondering somewhat the same thing as Ms Burke. Is cholesterol implicated in heart disease or not?
    Also, if I cut my statin dose to 40, vs 80, would I be significantly better off?

    • carolat538

      statins are deadly Your Brain need cholesterol more so as you age

  • Ruth Kinsella

    Four out of five of my brothers had heart attacks in their 60’s. {The other one had a cva in his 80’s}. They all had healthy cholesterol, good healthy mostly home grown diet. Lots of exercise and fresh air.

loading symbol Loading More