Category: Science

statins_increase_brain_hemorrhage_risk

Statin Drugs Increase Risk for Brain Hemorrhage

We are seeing ever-increasing efforts to make us believe that lowering our cholesterol is always going to be a risk-free event…and these efforts are working. Statin drugs to lower cholesterol have become among the most popular medications in the country!

But it’s really important to see what our most well-respected scientific journals are telling us about these drugs. In a meta-analysis study, researchers found that those individuals taking what were considered “higher dosages” of statin medications had more than a 50% increased risk for bleeding in their brains (intracerebral hemorrhage).

I’d really like for you all to take a look at the study. It might help someone you know rethink the idea that these medicines are without risk.

As a neurologist, I’ve had to care for countless patients over the years who had experienced a cerebral bleed, and it’s often a devastating event. Seeing this study calls attention to the notion of disease prevention that needs to be weighed on the other side of the supposed benefits.

  • Mary Ruth Kowalczyk Kolk

    I will be presenting a class to senior citizens on Tuesday: Statins: What you don’t know could hurt you. My husband had a horrible reaction to Pravachol. He could barely walk just weeks after beginning that statin. When I called the doctor, I was told that he should just take tylenol and eventually this would subside. Well, he took Tylenol and it didn’t subside. I saw my husband wilt in front of me like a flower that had not been watered on a hot summer day.

    Shortly after he started taking the statin, I also notices how he slowed down at our usual walks on the track at our gym. He would normally walk a lap on the track (which is 1/12 of a mile long) in about 1 minute 30 seconds, it was now taking him nearly 3 minutes per lap. He said his muscles hurt him too much and stopped after 4 laps. I called the doctor again and told him that I was concerned about Rhabdomyolysis and that I wanted my husband to get a blood test. Doctor told me there was nothing to worry about and again to take Tylenol or Advil and the muscle pain would go away.

    My husband insisted that we keep our commitment to family and friends and so we went on a scheduled vacation to a cabin at our nearby state parks about an hour and a half from our house. I watched as he turned down the other guys offers to play golf, something my husband looks forward to while on vacation. One morning I woke up to find my husband standing near our bed. He looked terrible. I asked him if he was okay. With tears in his eyes, he said that last night the muscle pain was so bad that he could not sleep. He wanted to go into the living room and watch TV but when he went to bed last night, he dropped his clothes on the floor. When he tried to reach down to pick them up…he couldn’t do it. He tried twice but the pain was so bad he could not reach down to pick up his clothes!

    I called the doctor that morning at 9AM I told him to order the CPK test for my husband and that we were coming home now to get that test done. He agreed with me. After hours of waiting the test results were negative according to the doctor. But, he told me that he wants my husband off the statin right now. Do not take another one. I found that unusual because I heard you’re not supposed to come off statins cold turkey as that may cause a heart attack. We stopped the statins that day.

    My husband’s muscles hurt him for 6 months AFTER he stopped the statin!!! SIX MONTHS! And he’s one of the lucky ones. At least after 6 months the pain finally went away for some people it never goes away.

    BTW I asked the doctor if he ever presented what happened to my husband to Medwatch. He said, “No.” I was aghast! So all you hear about is that there are only minimal percentages of people who have side effects from the statins – that’s because the doctors do not report the data to Medwatch.

    I’ve done a lot of research ever since this happened in 2011. I’ve found out how dangerous this medication can be especially when it is used as a preventative. I present my classes and let people in on what happened to my husband, what my research uncovered and how the most important thing they need to remember is that they must become empowered patients. They must be a proactive partner with their doctors in their own healthcare. Ask, ask, ask you doctor questions.

    I hope this helps someone. Thank you, Dr. Perlmutter. You were an important resource in my research on statins. Keep up the good work.

    • VSB

      Thank you for sharing your husband’s experience. Mine, too, had similar problems whether he took Lipitor, Crestor or Zocor. Luckily, our doctor was cautious and would have my husband immediately stop taking the offending medication. His cholesterol is very high in spite of leading a very active lifestyle and eating a healthy diet. He’s decided he’d rather live with the risks of the condition than suffer permanent damage from statins.

    • Jane Jewell

      Thanks for the warning! I had a series of eye strokes a few years ago, which were “probably caused by heart disease”. My doctor suggested I go on Statins. I refused.
      After two years of extensive tests to see what was wrong with my heart, they decided there was nothing whatsoever wrong. Another doctor diagnosed an autoimmune disease, Susac’s or something similar, as the cause of the eye strokes and damaged retina.
      Had I taken Statins, it would have been for no reason whatsoever.

      • crandreww1999

        Jane, and they would not have benefit you in the least, and quite likely may have caused a lifetime of adverse effects…

      • AnnieLaurie Burke

        Good for you! Statins, btw, have not been shown in any way, shape, or form, to benefit women, much less women with no risk factors.

    • Sharon

      Mary, I live in New Zealand. My husband was on statins for 16 years following an infarct, with nothing much happening for about the first 13 years but then he lost his sense of taste and his fingers became exquisitely painful and sensitive to touch which was devastating for him. He took himself off the statins as he suspected them being the cause (he is a doctor though now retired) but the major damage of taking them for all those years soon became apparent. One day I found him in our kitchen sitting at the lunch bar in tears. He said he felt like he was dying and he had not the smallest amount of energy. I took him to hospital but they could find nothing wrong except possibly some thrush!!! I did my own investigation and found out just how damaging statins are. He had been off them by then about 3 months and of course his GP and the hospital thought that was very risky! The first thing I did was start him on Coenzyme10 – Ubiquinone 200 mg daily which had almost miraculous effects in giving him back his energy and after 6 months he actually tasted a banana for the first time in years!!! However he became very sick last year (being 3 years post statins) with 5 separate things in a very short space of time and then he had a stroke! All in 2 weeks! His body having been “statinized” so long just could not cope with the sudden stress of it all. He has recovered quite a lot but speech and balance is a real problem. I blame statins for it all!!!
      If I had any influence on anybody my firm advice would be “do not touch statins if you value your life and your quality of life.” The drug company CEOs and doctors who push them should be strung up. They DO know better.
      Statins are the thalidomide of the 20th century.

      • Mary Ruth Kowalczyk Kolk

        Oh, thank you for reminding me about the CoQ10! Yes, very important!! My husband has also been on that since he went off the statins. You are also right about “statins are the thalidomide of the 20th century.” Every where you look another nursing home to service people with Alzheimerzers. The classes that we present are 80 minutes long once a week for 6 weeks. I can not believe how many people who come to our classes do not know the first thing about statins and how those drugs can actually cause you major damage. I also can’t believe that our doctor never reported what happened to my husband to MedWatch! Thanks again for the reminder on CoQ10. I hope everyone reads this and realizes how important that enzyme is.

  • Nan

    My husband suffered a cerebral infarction some 8 years ago and since then he is on a 80mg statin! He was told by his neurologist that he should continue with taking it indefinitely. He also takes a platelet anti-coagulant.

  • crandreww1999

    Mary Ruth I am an admin in a Facebook group for Statin Effects Sufferers, ourrently there are nearly 500 people worldwide, and growing daily…ALL but 1 share a similar story, their prescribing doctors tell them in response to their complaints ” Statins dont do that”..My Critical care Nursing career of 12 years was ended when 10mg Lipitor for 3 years, caused in me a Mitochondrial DNA mutation, Neuronal Apoptosis (Programmed brain cell death), peripheral neuropathy and for the past 14 years, profound pain, significant cognitive impairment, short term memory recall, and a whole lot of anger at the Medical establishment completely refuting the notion that these “wonder” drugs, could cause anything but rainbows and puppy dogs. I invite you to check out http://www.facebook.com/groups/statins there are a few Cardiologists who know the truth of these drugs (Dr Barbara Roberts MD, a Cardiologist of 30+ year) and (Dr Aseem Malhotra MD, a Cardiologist in England for 20+ years, also 2 Biochemists, 2 Pharmacists and plenty of victims

    • bendrichard

      Triglycerides are a better indicator of heart & arterial disease than gross cholesterol plus its the ratios between the items on a typical lipid panel.

      It is the ratio between the level of HDL-“good” cholesterol and total cholesterol that we need to be concerned about.
      Therefore, in adults, the HDL-“good” cholesterol/total cholesterol ratio should be higher than 0.24 (just divide your HDL level by your cholesterol).
      Or more precisely, the HDL/total cholesterol ratio:
      • 0.24 or higher is considered ideal
      • under 0.24 – low
      • less than 0.10 – very dangerous.
      Generally speaking, the higher the ratio, the better (the lower your risk of a heart attack).
      However, HDL is closely related to triglycerides.
      It appears common for people with high triglycerides to have low HDL’s, and these same people also tend to have high levels of clotting factors in their blood stream, which is unhealthy in protecting against heart disease.
      Therefore, in adults, the triglyceride/HDL-“good” cholesterol ratio should be below 2 (just divide your triglycerides level by your HDL).
      Or more precisely, the triglyceride/HDL ratio:
      • 2 or less is considered ideal
      • 4 – high
      • 6 – much too high
      • And, since HDL (high density lipoprotein) is protective against heart disease, the lower the ratio, the better.
      In other words, the lower your triglycerides, or the higher your HDL, the smaller this ratio becomes.
      It is now believed that the triglycerides/HDL ratio is one of the most potent predictors of heart disease.
      A Harvard-lead study author reported:
      “High triglycerides alone increased the risk of heart attack nearly three-fold.
      And people with the highest ratio of triglycerides to HDL — the “good” cholesterol — had 16 times the risk of heart attack as those with the lowest ratio of triglycerides to HDL in the study of 340 heart attack patients and 340 of their healthy, same age counterparts.
      The citation stated, the ratio of triglycerides to HDL was the strongest predictor of a heart attack, even more accurate than the LDL/HDL ratio.
      Supporting Citation:
      Gaziano JM, Hennekens CH, O’Donnell CJ, Breslow JL, Buring JE. Fasting triglycerides, high-density lipoprotein, and risk of myocardial infarction. Circulation. 1997 Oct 21;96(8):2520-5.

    • Mary Ruth Kowalczyk Kolk

      Thanks. I will check out those doctors and their web sites. I am always looking for solid information. I appreciate your sharing.

      • crandreww1999

        Also read as much as you can by cardiologists Dr Aseem Malhotra, Dr Peter Langsjoen, Dr Malcolm Kenrick, Dr Steven Sinatra, Dr. Duane Graveline (www.spacedoc.net)

  • Diane Tomkins

    What is considered higher dosages? That would be important information to me.

    • Betsy

      All of them.

      • Diane Tomkins

        I meant in the article. If it meant all of them it wouldn’t have said higher. Higher than what? So the question still is what did the author mean by higher dosages.

  • Desiree Reiach

    My husband was recently diagnosed with a familial form of cholesterol and the doctor prescribed Crestor. I was horrified because of the controversy surrounding statins and told my husband we would tighten up on our grain free, sugar free lifestyle which we started two years ago. He told me the doctor is fully aware that we are following Dr. Perlmutter Grain Brain lifestyle however, the doctor stated this will not help as the excess production of cholesterol is an inherited condition from his parent and nothing to do with diet. The doctor told him that he himself is on Crestor and if my husband does not take the statin he is at an increased risk of not only heart attacks but also strokes. To date my husband has not taken the Crestor we are waiting to meet with the doctor together. He is 63 years old in excellent health in every other way. I am frightened that my resolve will crumble with the fear that my husband may suffer heart failure without the reduction of cholesterol. I am not confident in my knowledge of statins when the issue is inherited. What can we say when we meet his MD?

    • crandreww1999

      Desiree, may I suggest before considering letting your husbands doctor force these pills upon you, a Book “The Truth About Statins: Risks and Alternatives to Cholesterol Lowering Drugs” by Dr Barbara Roberts, a Cardiologist of 30+ years who discusses the very real and tedious benefits these drugs have as well as their life altering adverse effects. If your doc prescribes a cholesterol drug, Google the phrase _____Has not been shown to prevent heart attack or heart disease….Fill in the blank with the name of the statin, or Zetia, and if he/she wants to use you as a guinea pig the the new, PCSK9 inhibitors, google “The effect of Repatha (or Praluent) on heart problems, such as heart attacks, stroke, or death, has not been determined.”

      • Desiree Reiach

        I will be investigating your resources and really appreciate your assistance with this confusing situation. Thank you so much for taking the time to comment.

        • crandreww1999

          Desiree, and Anyone, I have been disabled going on 15 years from the unpublished, underrecognized adverse effects of these Cholesterol drugs, and as a former critical care RN, I have poured thousands of hours into researching Statins, Cholesterol etc…if anyone would like me to share the information I have found, please send an email to crandreww1999@yahoo.com and I will be happy to share to get the truth out…

    • Suzanne

      Just because someone has high cholesterol, doesn’t mean they are destined for heart disease or a heart attack. I am wondering what happened to your husband’s parent regarding his/her high cholesterol. Did they use statins? Did they have a heart attack? Did they ever have their heart arteries checked for calcium build-up?

      Aside from knowing those questions, I would think the first thing for your husband to do would be to get his heart arteries checked for calcium build-up. It’s a super easy and inexpensive test, and it shows whether or not there is plaque building up in the arteries. You can read more about it here: http://www.webmd.com/heart-disease/cardiac-calcium-scoring#1

      Also, I have read where autopsies have been done on people who died in car accidents, showing that they had major artery blockages. In other words, they didn’t die from their apparent high cholesterol. I realize this probably makes things more confusing, so good luck, and I hope everything works out in your husband’s favor!

    • Mary Ruth Kowalczyk Kolk

      When you meet with your husband’s M.D., tell him you want a cholesterol “particle test.” This is done with the very same blood test as for the typical cholesterol test and the particle test should also be covered under your health insurance.

      HDL is analogous to large fluffy cotton balls. HDL picks up the small dense particles of cholesterol and returns them to the liver for reprocessing. LDL Particle “A” are also large fluffy type of cholesterol particles. LDL Particle “B” are the small dense, BB like cholesterol particles. Particle B are the culprit here. They can nick or get embedded under the endothelial tissues of the arteries and cause inflammation in that area. It’s like what happens when you cut or scratch your skin. Very soon after that happens areas around the cut or scratch become red because of inflammation. Within a few days a scab forms and healing begins. When that scratch or cut on your skin happened, your white blood cells are called into action. They surround that insult to the body and begin the healing process. Part of that healing process is the scab that forms. That’s what happens when small dense Particle B’s invade your endothelial tissues (the very thin top of the three layers of lining protecting your arteries). That insult summons the white blood cells to get to work and heal that area. The results of the artery or vein sustaining insult after insult is the build up of tissue/scab. If the build up on that weakened area breaks off you have a blockage in that artery. That is why you want to know is what is your husband’s Particle B.

      A total cholesterol panel that presents the combined HDL and LDL cholesterol counts i.e., “Cholesterol Levels” 240 does not tell you anything at all. You need to know Particle counts. Ask your doctor. Your doctor is your guide. I am not a doctor, or a nurse nor do I hold any medical degree or license. I am simply passing along information that I have gleaned through research.

      What is amazing to me is low carb diet and exercise will lower your LDL Particle B and increase your HDL and LDL Particle A. Again, check with your doctor before making any changes to your diet, lifestyle or exercise.

      A total cholesterol panel that gives you the combined HDL and LDL and for example presents your “Cholesterol Level” at 240 is not telling you anything at all. You need to know your particle count.

  • Norman

    If one doesn’t want to take statins, then how do you lower cholesterol?

    • Patricia Taylor

      Not really sure that it needs to be lowered. It is sugar that is the biggest culprit in heart disease.

      • Betsy

        Red yeast rice lowered mine 33 puts in two mths=dr was angry??my mom has low cholesterol & died after 2 strokes. ☠dr

      • Ed

        Treat the cause not the symptom. Change what you put in your mouth. Read Grain Brain!

    • Symin

      Please read The Cholesterol Myths by Uffe Ravnskov before you believe that it actually needs to be lowered. Unless you have the rare genetic mutation that causes levels to rise wayyyyyy high, it’s more likely you have been sold a bill of goods. We NEED cholesterol for our brains to work properly.

      • Patricia Taylor

        Absolutely! I sometimes wonder if all of the Alzheimers disease does not have some kind of a connection with the fact that everyone is on statins.

        • Sharon

          It does Patricia! I used to work as a doctor’s nurse and noticed most of his patients who had Alzheimer’s or dementia or Parkinson’s Disease all had reasonably low cholesterol (because they were ALL on statins). It’s no wonder they developed those diseases with the cholesterol lowering medication. Trouble is my boss (Dr) wouldn’t even discuss the matter. He thought I just “had a thing about it”!!!

      • Patricia Taylor

        Speaking of a rare genetic mutation, I have a genotype 3/4 combined with a high lipoprotein a, which are things that your general practitioner knows nothing about. The cardiologist I had been going to no longer is actively practicing but told me that people with those two genetic profiles do better on statins. Does anyone have any advice about that? Thanks.

    • Betsy

      Betsy

      • Patricia Taylor

        My Mom went into cardiac arrest and did not have high cholesterol either.

        • Betsy

          The most damaging part of my life for the last 30 years has been the medical world. My Dad, very healthy was killed (bled him to death) for a minor-type surgery.
          My health —I don’t have the words—these doctors have taken so much from me. I am determined to get my health back and have been going to Begman Wellness in Huntington Beach, CA.
          YouTube (check out Dr.Bergman Chiro —good g00d people—I meet people from all over the world there.
          This guy talks about every subject—tom. he’s giving a community lecture on the myths they don’t tell you about vaccinations (he cares so much bec, hes suffered ffrom doctors.
          Im a trauma therapist and treat people who have psycho-genic seizures (high PTSD). We have to use our energy to go against harm. There are 50,000 psychiatrists and they are the worst.
          Im sorry for your loss Patricia—I hope you can counter with the goodness you put out in life.

    • Sharon

      Norman, you don’t need to lower cholesterol. You need it; it’s made as part of a flow on effect at the cellular level to be available for all the body hormone requirements. It’s another crime foistered onto people – making out cholesterol is a disease!!! You need to check it out as there is more to it than I can put in this reply. This site should have articles on its importance. Check out “How Statin Drugs Really Lower Cholesterol And Kill You One Cell At A Time” by Dr Hannah Yoseph, MD and James B Yoseph. An excellent book giving you all the information you will need to show you just how important cholesterol is to a healthy life. I think I bought mine through Book Depository in England but it should be available through Amazon in USA.
      Cholesterol makes up a large part of the brain. What do you think happens when the brain cannot get enough? Right on! Parkinson’s Disease, dementias and other neurological disorders. You need a good amount of vitamin D on board too so your body can make adequate amounts of cholesterol. It’s a basic requirement!

    • AnnieLaurie Burke

      Why do you want to lower cholesterol? Unless you have hypercholesteremia, what advantage do you see in lowering cholesterol?

    • shirleycolee

      Eat lots of non-starchy especially green, leafy vegetables, low sugar fruits like berries, high fiber foods, a little flax oil, coconut oil, fish oil – Omega 3 fats, no trans fats, little or no saturated animal fats (meat, whole fat dairy), have some non fat yogurt, eliminate sugar and empty carbs, exercise daily, keep weight off, especially belly fat. You’ll have a desirable blood cholesterol profile, low on the bad LDL and high on the good HDL and low on the bad triglycerides. You don’t need meds, just good health behaviors.

    • Cambooya

      You lower your cholesterol by cutting out all carbohydrate foods and increasing your fat intake. For 6 month I ate 500 grams of butter a day, 20 grams of carbohydrates max and 120 grams +/- of proteins depending on exercise. My blood panels today are perfect after 2.5 years. I no longer eat 500 grams of butter, but 75 percent of my calorie uptake is from saturated fats…meats, dairy fats, butter, coconut oil, avocado oil and olive oil. My carbohydrate intake is still 20 grams or less a day and my blood panels are still perfect and my weight is 5 pounds above my ideal weight for age/height. I’m 66 by the way.

    • David Perlmutter

      I am not one to want to lower cholesterol, even naturally.

      • Sandra

        What if a carotid artery is blocked with plaque? Is this situation not connected to high cholesterol? What do you recommend to clear the blockage? Is it safe to stop taking Crestor in this case?

      • Laura

        Dr. Permutter, I agree with you overall about lowering cholesterol, but what is your take on high LDL-P or ApoB increasing with a very low carb, generous saturated fat diet? Dr is pushing statins, which I am strongly resisting. I’m trying to lower the liproprotein particle number by subbing a greater portion of saturated fats for MUFAs and non-industrial PUFAs. Also adding flax seeds, chia seeds, etc. for more fiber. Should I be concerned? I, myself, have some neurological issues, and my dad died recently of Lewy Body Disease, so I don’t want to do anything that might make things worse.

  • Dr Jeff

    https://www.ncbi.nlm.nih.gov/pubmed/25672965

    May want to read this as well.

  • Deborah Zebrowski

    I also had similar reaction to Lipitor. I was given lipitor by my cardiologist also as a preventive & on smallest dose. I am 60 yrs old. I began having lower leg pain & weakness within about a week or two. I never new about this connection to the statin. I believe I took it for 6 months. I was seeing a Neurologist for another issue & at my 6 month f/u she was shocked at my decline. I was barely able to walk. She ran tests on me thinking I had MS. When my tests came out negative, she asked had I began taking any new meds. I mentioned the Lipitor, never realizing it could be that. She took me off of it that day. I was very blessed as all symptoms went away within 2 weeks! But I was shocked! I made sure my Cardiologist was aware. He told me he never heard of such an extreme reaction but was glad I let him know. I also found out this weekI had a bleeding ulcer. After reading about the brain bleed, I wonder if it also caused my bleeding ulcer. Thank you for the article & hope it will cause more people to be proactive about their health & not be afraid to question any meds which you are given. After all, we are our own best advocate!

    • crandreww1999

      Deborah, what I find troubling with that, is no statin has ever proven to benefit a woman of any age, and NEVER in Primary Prevention(Preventing a first heart event).

  • John Dryja

    I survived a “brain bleed” about a year ago. I thought my life was over. My entire right side was effected. I was taking pravastin. I remember when I started taking it my cholesterol was good but Doctor wanted me to take it for “insurance”. Should I find a lawer?The bottom line is because of my brain bleed,I went from earning 800 dollars a week, to surviving on 800 a month disability. So I see this email and now my wheels are turning. I stopped taking it a while ago because it made my gas “wet” so to speak while I slept. I do not wish to sound gross, but for lack of a better analogy, since I stopped taking it,no more wet,chunky, farts while I was asleep in bed

    • AnnieLaurie Burke

      Find a lawyer! I think we are an over-litigious society, and that there are far too many frivolous suits, BUT…. Sadly, it is only by holding these doctors and pharma companies accountable that we will prevent these tragedies. I hope you continue to recover, and will be able to return to your career. No one should have to endure such a potentially lethal symptom as your brain bleed, nor one that destroys one’s basic human dignity, such as your other problem.

      • John Dryja

        thank you

  • Patricia Taylor

    My biggest concern with all of this is the fact that doctors for the most part refuse to believe, or admit, that statins and other drugs as well, cause side effects.
    It makes the patient feel like an idiot.

    • crandreww1999

      Patricia. of the 2500 in the fb Statin Effects group, ALL but one Gentleman from Denmark, have the same story, our doctors have replied “statins dont do that”…yet, they do, if you took the time to not listen to the drug reps sales pitch as Gospel truth, and read and discerned the literature for yourselves

      • Patricia Taylor

        That is so true. You have to be your own best advocate. I always research my medications. One doctor told me to get off the internet and to stop looking for these problems.

    • David Perlmutter

      That’s why we, as a community, must continue to advocate for this!

      • Sandra

        Hi Dr. Perlmutter – I went to a Neurologist and he found that my left carotid artery was narrowed by 50 percent. He prescribed Crestor 10mg. I don’t like taking it but he inferred that I could get a stroke if I didn’t take it. He also said that a low cholesterol diet wouldn’t be enough to mitigate the risk. What do you suggest in my case? 10mg is a low dosage but there are still side effects, I would think?

    • Sandra

      I agree – my GP doesn’t acknowledge any serious side effects from Crestor or any other drug, it seems. It is very frustrating.

  • I eat a high fat, high salt diet with LITTLE OR NO SUGAR and have no diabetes, no heart disease and no arthritis – when I see the guvmint recommend how we should eat, I generally do the opposite with good results
    BTW, you can watch certain cable TV shows and one minute see an ad for some new drug (to treat some new fictitious disease) and not long afterward see an ambulance chaser ad for a class action lawsuit to that same drug due to long term health injury or death

  • Grace Moenich

    I’m actually posting as Jeff Moenich, Grace’s father. My father suffered a mild heart attack about 5 years ago and was put on Lipitor. Within a year he was dx with a liver tumor, biopsy showed high grade neuroendocrine which was also found in his prostate. He was dx with adenocarcinoma of the prostate approx 8 yrs before this. Thanks for posting this article, Dr Perlmutter. I would be interested in seeing this study about increase risk for cerebral bleeds, as well as the medical community really evaluating if the statins are beneficial or just a cause of many other medical problems from the side effects.

  • AnnieLaurie Burke

    So, since even the FDA says that dietary cholesterol is no longer a constituent of concern, and since numerous studies have found that, for people over age 65, higher serum cholesterol is correlated with lower all-cause mortality, why, in the name of common sense, are we still obsessed with LOWERING everyone’s cholesterol level??? This should only be a recommended treatment for people that have genetic hypercholesteremia.

  • Deb S.

    My husband has been on a statin for 15+ years. He was diagnosed with Parkinsons Disease 2 1/2 years ago. Is there a correlation between statin use and Parkinson’s Disease?

    • Tara

      I can’t get any Doctor to say statins mess with brains but I believe it. My husband was put on statins when he was found to have type 2 diabetes. We were told “it’s a numbers game…keep blood sugar, blood pressure, blood cholesterol low and all will be well. After a few years I would find him staring at the computer for hours in a trance. He could not address a letter in an ordinary way and he could no longer drive a car. I knew something was very wrong so I started looking more closely at the drugs and came away blaming the statin. He was finally diagnosed with Lewy Body Dementia, which is somewhat like Parkinson’s. He was a member of MENSA when he was young and now he can’t put his own clothes on. I can’t prove it but I know it in my heart, statins did this.

      • Deb S

        I’m sorry this happened to your husband Tara. It’s just not right that we are misled and misinformed by people and institutions that we are expected to trust. It’s very discouraging. There is an article that came out November 13, 2016 encouraging physicians to screen everyone over the age of 40 for possible statin use regardless of whether they have a history of cardiovascular disease.
        These new guidelines for statin use are scary!
        https://www.washingtonpost.com/news/to-your-health/wp/2016/11/13/new-statin-guidelines-everyone-age-40-should-be-considered-for-the-drug-therapy/?utm_term=.c19567d57590

      • Helga

        My heart goes out to you. But there is hope. I saw a youtube video a few months ago where man could not draw a clock. His wife ( a doctor) decided to give him two spoons of coconut oil everyday. She shows the clock he can now draw which is a damn good drawing, with hands and everything. He can talk normally. Unfortunately, I cannot remember the doctor’s name but I think it might be Dr. Mary Newport

        Check out youtube:

        Coconut Oil As an Alzheimer’s Treatment – Dr. Mary Newport

        I’m taking coconut oil too after my brain hemorrhage from Symvastatin which I have stopped. Good luck Tara, give coconut oil a try for at least 6 to 12 months. And see the video. If you see in the video about a drawing of a clock then it is the video I have in mind. Will write again if I find the video. Please try Coconut oil. It has healthy cholesterol and people in Africa and Asia have been eating coconuts for centuries.

  • Mary

    I have frequent PACs and wide complex tachycardia consistent with atrial tachycardia with aberration. My Dr. wants to put me on a beta blocker, but I don’t want to. It would make my asthma and Raynaud’s worse, plus I just don’t want to be on one. Is there something natural like supplements I can take or use like essential oils that will help me instead? Thank you!

  • Diane

    My mother went into heart failure and simultaneously lost the use of her hand and arms. Statins caused heart failure and permanent nerve damage after 6. Years of use. She is 77 and has now lost her home ability to drive dress and wash herself.
    If statins were not dangerous then ask yourself how products like “statin smart” are on the market . A product that collects your DNA to determine if a person can tolerate stain drugs. I know that this didn’t happen to my mother it was DONE to her by statin drugs.
    There is research done by Stephanie Senoff head of the biology department at M.I.T. . I suggest anybody who is either on statins or considering them read her research. Statins are dangerous, . They suck the fat right out of you. The Brain is 90% fat without it the brain will begin to die causing an increase I. The incidence of MS ALS Parkinson’s and Alzheimer’s disease .
    I also recommend purchasing the documentary “Statin Nation” created by cardiologists who reveal the lies , the medical money making scam and the damage statins can cause .
    My mother has been off the drug for a year. Thanks to alternative medicine the damage has been reversed but unfortunately, she sustain permanent paralysis due to extensive danage to her nerves at the cellular level and her aeortic valve literally crumbled requiring a valve replacement.
    Her only hope will be embryonic stem cell transplant to repaire the damage. If anyone out there has knowledge regarding the best hospitals for embryonic stem cell transplant please respond.
    Stan drug distribution needs to end. It destroyed my mother’s heart the very organ it was supposed to protect!!! The distribution of statin drugs are nothing short of a nazi war crime!

    • Helga

      I suffered a brain hemorrhage two months ago. Recovered pretty well. Strangely, on the day I had my stroke, my boyfriend received Perlmutters newsletter warning about Statin which I’ve been taking for over a year. Doctors at the hospital insisted I must have fallen on my head. I and my boyfriend said no, but they wrote it in there report that a fall must have caused the hemorrhage. I told my doc about statin. She said no way, it must be the fall (which I never had. ) I’m now taking two spoons of coconut oil everyday for my brain.

  • Nancy Ingunza

    Dr. Perlmutter, I am taking Simvastatin for high cholesterol for almost 5 years, I am very concerned now that I have read this Article, my question is what should I take instead of the Simvastatin.

    • crandreww1999

      Nancy, you taking a statin, deeply concerns me. I was disabled 15 years ago at the age 34, due to unpublished, effects of statins, In me, they caused Neuronal Apoptosis (Programmed brain cell death, Mitochondrial DNA mutation, and Peripheral neuropathy) all confirmed by Drs Beatrice Golomb MD, of the UCSD Statin Effects Study. I was a critical care RN of 12 years, prior to succumbing to the Statin I took. I would recommend you read the book, “The Truth About Statins: Risks and Alternatives to Cholesterol Lowering Drugs” by Dr Barbara Roberts, MD, a Cardiologist of 30+ years who knows the real truths of Statins and the Cholesterol theory of heart disease. For instance, I am certain your prescriber is not aware that NO STATIN, has ever proven to prevent heart disease in Women. And in men, they provide a small reduction when used as Secondary Prevention, (Never in Primary prevention, which is trying to prevent a first heart attack). I am an admin in a Facebook group for Statin Effects Sufferers, I invite you and anyone else who wants to know the truth about these drugs effects to join http://www.facebook.com/groups/statins

  • Crystal Cates

    Hello…..I am looking for help on the subject of statins. Every time I think I have a good understanding of what I need to do, something comes up to make me question myself!
    I am a 52-year-old female with no other medical problems.
    My cholesterol numbers have climbed significantly over the past year, especially my triglycerides…..going from 63 to 160.
    My total cholesterol is now 238, LDL is 155 and non-HDL is 187. I asked my doctor if diet/exercise could help me, but he said no……I just have bad genes and he put me on Atorvastatin.
    Coincidently I was reading Grain Brain at the time and became concerned about taking a statin.
    I then began to have awful muscle aches and I stopped taking the Atorvastatin…..the doctor then tried putting me on Livalo, but my insurance would not cover it so now he wants me to go back on the
    Atorvastatin. I am refusing, instead focusing on my diet and exercise
    and he says I am taking a big risk in doing so.
    I am wondering……Is it really impossible to get MY numbers in better shape with diet and exercise like my doctor says? Or am I hopefully on the right track in proving him wrong??

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