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Gut Bacteria Change Your Brain

I’m very excited to bring you this research study from my friend Dr. Emeran Mayer. It’s a very intriguing report that demonstrates not only how changes in the gut bacteria correlate with irritable bowel syndrome, but, in addition, how these changes in the gut bacteria correlate with the size of various brain areas.

In addition, the authors were able to correlate how the changes observed in the gut bacteria actually linked to early life trauma. This seemingly connected the dots between early life trauma and the observed differences in brain morphology.

I understand this may sound complicated, but hopefully the video will make this more understandable.

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  • Emmalee

    Early life trauma……..can you provide examples? I can’t bring up the research data/study.

    • TechnoTriticale

      re: I can’t bring up the research data/study.

      It appears to be here, open-access:
      “Differences in gut microbial composition correlate with regional brain volumes in irritable bowel syndrome”
      https://microbiomejournal.biomedcentral.com/articles/10.1186/s40168-017-0260-z

    • Lynn Dell

      The research is quite complex. It appears early trauma has been studied in animal models, but the correlation in humans was hard to understand from this study. Keep in mind the sample size. What jumped out at me like a coiled snake was the F B ratio, that is, the firmicutes to bacteroidites ratio. This ratio also tends to be the same in many who are obese, namely, that firmicutes tends to be much more prevalent in those who are obese, or have IBS. A question to consider is are there easy way to increase bacteroidites and decrease firmicutes? There are some suggestions on the internet about this. Looking forward to more articles like this. Thanks!

  • calle

    So has anyone studied neonates and gut and brain functions?
    This should be a very equal group of people.
    So people who get IBS late in life had childhood trama?

    Need to read the research!

    Who sponsored this research?

    • BarbaraDale

      Do you want some common sense? No, I never studied “neonates”, and I don’t even know what it is. I study whatever I have time to study. So, I know a little bit. I mostly experience my own body, and Mother Nature teaches me things along with the Holy Spirit—-a great teacher. My opinion (It’s all I’m authorized to give.) is—- No, IBS is not necessarily a determiner of early childhood trauma. IBS can be caused by lots of different things. But, I would say that at the heart and/or core of every IBS case there is a friendly flora problem or imbalance of microbiome. The two go together.

  • Luc Chene

    What would be interesting to know is if there was a psychological trauma, not physical, could the same be observed? Say a child loosing a parent in early childhood, or an abusive parent?

    • Ottavia Zeffilini

      Hi Luc, yes would think psych trauma would affect the microbes even more. I think/know the abusive parent situation all too well, a physical abuse not only affects the body but can have an even more damaging effect on the brain. I found this is to be extremely true with myself. It’s taken years to clear most of the abuse out of my brain yet it seeps out still but I’m able to catch it quicker now.

      • Sam Ha

        Hello Ottavia,
        I’m VERY interested in what you say about how abuse can have a damaging effect on the brain…what method did you use to clear it from your brain?? I would really appreciate that info for my personal work.
        Thanks!

        • BarbaraDale

          Will you please read my reply to Ottavia? I, also, would like to know more details about her “abuse.”

      • BarbaraDale

        Abuse. Please specify. We cannot see abuse. But, we feel it. Abuse is abstract. My synopsis: Abuse is stress. Stress is experienced by the body as a secretion of the adrenal medulla hormones. There are three main ones. An excess of these hormones (adrenalin is one) is very damaging to the body. An excess of these hormones causes inflammation, acidity, and weakens the immune system and causes more free radicals. So, I guess they would inevitably cause harm to the good bacteria and, in turn, alter the ratio of good vs. bad. So, when you say “abuse”, I need you to spoonfeed me. What do you mean by “abuse”? Do you mean pain from trauma? Or, do you mean past memories? Or, stress reactions?

        • Jal

          The Brain itself, not just the adrenal system, can have specific physical reactions to trauma e.g. PTSD which keeps the “memory” of trauma in a “holding pattern” that produces ongoing harmful mental and physical reactions see https://www.psychotherapy.net/article/body-keeps-score-van-der-kolk

          • BarbaraDale

            Of course! You’re “singing to the choir!” That’s why I wanted her to be specific. So, she could help me. I suffer from the same exact thing or experience, but I would describe it a whole lot more differently than she did. I would not use the word “abuse”, even though, in the beginning, that was what it was—abuse. Abuse is the behavior that causes the pain, in our cases —- the trauma. I was abused by my mother multiples of times when I was five and/or six years old. In my childhood I forgot about it. But, I understand memory. The immune system has memory. Cells have memory. And, not only that, I was abused in the worst way. There are myriads and myriads of different kinds, types, and degrees of abuse. I’ve been dealing with this all of my life. I have let Mother Nature, the Holy Spirit (the Spirit of Truth), my personal studies and research, and a licensed homeopathist be my teachers. I would like to write a book on my experiences and on what I believe and know, but cannot because I’m dealing with a combination of handicaps and chronic illnesses (neurodegenerative disease); and I’m not able to do much except take care of myself, try to keep regenerating, and keep on extending my life, because, as we speak, I am not supposed to be alive. I believe at the heart and core of every piece of trauma is the adrenals. The adrenal hormone(s) reach the brain in nano seconds. The brain, of course, is where we feel it. It’s the hypothalamus-pituitary-adrenal axis. All of this damage I suffer, 100% of it, was caused by that one thing—trauma and the drug behind it. Bad stuff!

        • eileenfb1948 .

          Abuse causes a stress reaction. So,do other events which are not abusive. The deciding factor is to ask, is this an excessive response from my body? Heart pounding keeping you awake, whatever the cause, is still stress. An area worth googling.

    • Jal

      The 2 are inseparable: where one is the other is… even if a study did not measure fr both.

  • Jal

    From recent research I have learned:
    1. the brain is plastic so its morphology CAN be changed
    2. Gut microbiome is also structured from birth (&pre-birth) but is is adaptable as an internal environment /eco-system
    3. whilst interestingly correlated, adverse changes between 1-2 are not set in concrete and can be manipulated by considering the external inputs: food meds sleep lifestyle etc all of which affect the delicate balance at any point in time.
    Genetics are likely factor too since gluten appears to be major disrupter to some but not all people.. I (am sorry I) cannot provide direct references to this summary.
    But our modern life (bad) habits are re-setting the direction of which genes will evolve and which will not, with the the gut eco-system seeming to be a/ the major determinant…

    • BarbaraDale

      Well, I would like to know how the gut microbiome fits in with DNA (genetic) bio-markers such as foods, nutrients, etc. and epi genetics. The microbiome must itself be a DNA (genetic) bio marker. Can anybody explain?

      • Jal

        Yes! Recent research is concluding that! It’s showing the extent to which our microbiome is responsible for our genetic and epi-genetic expression… and its extremely surprising.. (for a start human genes number ~21,000 BUT our gut bacteria genes are estimated at 4.4 million …and that is a lot of possible variation). see http://alannacollen.com/in-print-2/10human/

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