MIND diet associated with reduced incidence of Alzheimer’s disease

Publication

Alzheimer's and Dementia

Author(s)

Martha Clare Morris, Christy C. Tangney, Yamin Wang, Frank M. Sacks, David A. Bennett, Neelum T. Aggarwal

Abstract

Introduction:
In a previous study, higher concordance to the MIND diet, a hybrid Mediterranean- Dietary Approaches to Stop Hypertension diet, was associated with slower cognitive decline. In this study we related these three dietary patterns to incident Alzheimer’s disease (AD).

Methods:
We investigated the diet-AD relations in a prospective study of 923 participants, ages 58 to 98 years, followed on average 4.5 years. Diet was assessed by a semiquantitative food frequency questionnaire.

Results:
In adjusted proportional hazards models, the second (hazards ratio or HR 5 0.65, 95% confidence interval or CI 0.44, 0.98) and highest tertiles (HR 5 0.47, 95% CI 0.26, 0.76) of MIND diet scores had lower rates of AD versus tertile 1, whereas only the third tertiles of the DASH (HR 5 0.61, 95% CI 0.38, 0.97) and Mediterranean (HR 5 0.46, 95% CI 0.26, 0.79) diets were associated with lower AD rates.

Discussion:
High adherence to all three diets may reduce AD risk. Moderate adherence to the MIND diet may also decrease AD risk.

Date

September 11, 2015

View study