Science

John D. Omura, MD; Lisa C. McGuire, PhD; Roshni Patel, MPH; Matthew Baumgart; Raza Lamb; Eva M. Jeffers, MPH; Benjamin S. Olivari, MPH; Janet B. Croft, PhD; Craig W. Thomas, PhD; Karen Hacker, MD

What is already known about this topic?
The 2021 National Plan to Address Alzheimer’s Disease (National Plan) included a goal to reduce the risk for Alzheimer disease and related dementias (ADRD).

What is added by this report?
Adults aged ≥45 years with subjective cognitive decline (SCD) were more likely to report four or more risk factors compared with those without SCD (34.3% versus 13.1%). Prevalence of SCD increased from 3.9% among adults with no risk factors to 25.0% among those with four or more risk factors.

What are the implications for public health practice?
Implementing evidence-based strategies that address modifiable risk factors can help achieve the National Plan’s goal to reduce risk for ADRD while promoting healthy aging.