FBPixel Peripheral Inflammation and Cognitive Aging - David Perlmutter M.D.


Study Title
Peripheral Inflammation and Cognitive Aging
Modern Trends Pharmacopsychiatry

Alvin Lim, Katarina Krajina, Anna L. Marsland


Evidence suggests that inflammation, an innate immune response facilitating recovery from injury and pathogenic invasion, is positively associated with age-related cognitive decline and may play a role in risk for dementia. Physiological pathways linking the peripheral immune and central nervous systems are outlined, and studies linking inflammation with neurocognitive function are overviewed. We also present recent studies from our laboratory showing that midlife inflammation is related to cognitive function and brain morphology. Finally, potential implications for treatment, future directions, and limitations are discussed.

July 1, 2013
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Dr. David Perlmutter is on the cutting edge of innovative medicine that looks at all lifestyle influences on health and illness.

Andrew Weil, MD